What is going on? Anatomy of an Epidemic challenges readers to think through that question themselves. First, Whitaker investigates what is known today about the biological causes of mental disorders. Do psychiatric medications fix “chemical imbalances” in the brain, or do they, in fact, create them? Researchers spent decades studying that question, and by the late 1980s, they had their answer. Readers will be startled—and dismayed—to discover what was reported in the scientific journals. Then comes the scientific query at the heart of this book: During the past fifty years, when investigators looked at how psychiatric drugs affected long-term outcomes, what did they find? Did they discover that the drugs help people stay well? Function better? Enjoy good physical health? Or did they find that these medications, for some paradoxical reason, increase the likelihood that people will become chronically ill, less able to function well, more prone to physical illness?  This is the first book to look at the merits of psychiatric medications through the prism of long-term results. Are long-term recovery rates higher for medicated or unmedicated schizophrenia patients? Does taking an antidepressant decrease or increase the risk that a depressed person will become disabled by the disorder? Do bipolar patients fare better today than they did forty years ago, or much worse? When the National Institute of Mental Health (NIMH) studied the long-term outcomes of children with ADHD, did they determine that stimulants provide any benefit?  By the end of this review of the outcomes literature, readers are certain to have a haunting question of their own: Why have the results from these long-term studies—all of which point to the same startling conclusion—been kept from the public?  In this compelling history, Whitaker also tells the personal stories of children and adults swept up in this epidemic. Finally, he reports on innovative programs of psychiatric care in Europe and the United States that are producing good long-term outcomes. Our nation has been hit by an epidemic of disabling mental illness, and yet, as Anatomy of an Epidemic reveals, the medical blueprints for curbing that epidemic have already been drawn up.

    David Starr Jordan was a taxonomist, a man possessed with bringing order to the natural world. In time, he would be credited with discovering nearly a fifth of the fish known to humans in his day. But the more of the hidden blueprint of life he uncovered, the harder the universe seemed to try to thwart him. His specimen collections were demolished by lightning, by fire, and eventually by the 1906 San Francisco earthquake—which sent more than a thousand of his discoveries, housed in fragile glass jars, plummeting to the floor. In an instant, his life’s work was shattered. Many might have given up, given in to despair. But Jordan? He surveyed the wreckage at his feet, found the first fish he recognized, and confidently began to rebuild his collection. And this time, he introduced one clever innovation that he believed would at last protect his work against the chaos of the world. When NPR reporter Lulu Miller first heard this anecdote in passing, she took Jordan for a fool—a cautionary tale in hubris, or denial. But as her own life slowly unraveled, she began to wonder about him. Perhaps instead he was a model for how to go on when all seemed lost. What she would unearth about his life would transform her understanding of history, morality, and the world beneath her feet. Part biography, part memoir, part scientific adventure, Why Fish Don’t Exist reads like a fable about how to persevere in a world where chaos will always prevail.

    Someday, we know, we will all die. And, we know, so too will the universe itself.Until the End of Time is Brian Greene's breathtaking new exploration of the cosmos and our quest to understand it. Greene takes us on a journey across time, from our most refined understanding of the universe's beginning, to the closest science can take us to the very end. He explores how life and mind emerged from the initial chaos, and how our minds, in coming to understand their own impermanence, seek in different ways to give meaning to experience: in story, myth, religion, creative expression, science, the quest for truth, and our longing for the timeless, or eternal. Through a series of nested stories that explain distinct but interwoven layers of reality-from the quantum mechanics to consciousness to black holes-Greene provides us with a clearer sense of how we came to be, a finer picture of where we are now, and a firmer understanding of where we are headed.Yet all this understanding, which arose with the emergence of life, will dissolve with its conclusion. Which leaves us with one realization: during our brief moment in the sun, we are tasked with the charge of finding our own meaning.Let us embark.

    Leslie Jamison deftly excavates the stories we tell about addiction--both her own and others'--and examines what we want these stories to do, and what happens when they fail us.All the while, she offers a fascinating look at the larger history of the recovery movement, and at the literary and artistic geniuses whose lives and works were shaped by alcoholism and substance dependence, including John Berryman, Jean Rhys, Raymond Carver, Billie Holiday, David Foster Wallace, and Denis Johnson, as well as brilliant figures lost to obscurity but newly illuminated here.For the power of her striking language and the sharpness of her piercing observations, Jamison has been compared to such iconic writers as Joan Didion and Susan Sontag. Yet her utterly singular voice also offers something new. With enormous empathy and wisdom, Jamison has given us nothing less than the story of addiction and recovery in America writ large, a definitive and revelatory account that will resonate for years to come.

    He asked them to disclose something that, for scientific reasons, worries them—particularly scenarios that aren't on the popular radar yet. Encompassing neuroscience, economics, philosophy, physics, psychology, biology, and more—here are 150 ideas that will revolutionize your understanding of the world.Steven Pinker uncovers the real risk factors for war * Mihaly Csikszentmihalyi peers into the coming virtual abyss * Nobel laureate Frank Wilczek laments our squandered opportunities to prevent global catastrophe * Seth Lloyd calculates the threat of a financial black hole * Alison Gopnik on the loss of childhood * Nassim Nicholas Taleb explains why firefighters understand risk far better than economic "experts" * Matt Ridley on the alarming re-emergence of superstition * Daniel C. Dennett and george dyson ponder the impact of a major breakdown of the Internet * Jennifer Jacquet fears human-induced damage to the planet due to "the Anthropocebo Effect" * Douglas Rushkoff fears humanity is losing its soul * Nicholas Carr on the "patience deficit" * Tim O'Reilly foresees a coming new Dark Age * Scott Atran on the homogenization of human experience * Sherry Turkle explores what's lost when kids are constantly connected * Kevin Kelly outlines the looming "underpopulation bomb" * Helen Fisher on the fate of men * Lawrence Krauss dreads what we don't know about the universe * Susan Blackmore on the loss of manual skills * Kate Jeffery on the death of death * plus J. Craig Venter, Daniel Goleman, Virginia Heffernan, Sam Harris, Brian Eno, Martin Rees, and more

    Coated in red dust, the terrain is bewilderingly empty. And yet multiple spacecraft are circling Mars, sweeping over Terra Sabaea, Syrtis Major, the dunes of Elysium, and Mare Sirenum—on the brink, perhaps, of a staggering find, one that would inspire humankind as much as any discovery in the history of modern science.In this beautifully observed, deeply personal book, Georgetown scientist Sarah Stewart Johnson tells the story of how she and other researchers have scoured Mars for signs of life, transforming the planet from a distant point of light into a world of its own.Johnson’s fascination with Mars began as a child in Kentucky, turning over rocks with her father and looking at planets in the night sky. She now conducts fieldwork in some of Earth’s most hostile environments, such as the Dry Valleys of Antarctica and the salt flats of Western Australia, developing methods for detecting life on other worlds. Here, with poetic precision, she interlaces her own personal journey—as a female scientist and a mother—with tales of other seekers, from Percival Lowell, who was convinced that a utopian society existed on Mars, to Audouin Dollfus, who tried to carry out astronomical observations from a stratospheric balloon. In the process, she shows how the story of Mars is also a story about Earth: This other world has been our mirror, our foil, a telltale reflection of our own anxieties and yearnings.Empathetic and evocative, The Sirens of Mars offers an unlikely natural history of a place where no human has ever set foot, while providing a vivid portrait of our quest to defy our isolation in the cosmos.

    From diet and productivity to decorating to social interactions, they try it all, record themselves along the way, then share what they’ve learned with their devoted and growing audience of fans who tune in.In How to Be Fine, Jolenta and Kristen synthesize the lessons and insights they’ve learned and share their experiences with everyone. How to Be Fine is a thoughtful look at the books and practices that have worked, real talk on those that didn’t, and a list of philosophies they want to see explored in-depth. The topics they cover include:Getting off your deviceEngaging in positive self-talkDownsizingAdmitting you’re a liarMeditationGoing outsideGetting in touch with your emotionsSeeing a therapistBefore they began their podcast, Jolenta wanted to believe the promises of self-help books, while Kristen was very much the skeptic. They embraced their differences of opinion, hoping they’d be good for laughs and downloads. But in the years since launching the By the Book, they’ve come to realize their show is about much more than humor. In fact, reading and following each book’s advice has actually changed and improved their lives. Thanks to the show, Kristen penned the Amish romance novel she’d always joked about writing, traveled back to her past lives, and she broached some difficult conversations with her husband about their marriage. Jolenta finally memorized her husband’s phone number, began tracking her finances, and fell in love with cutting clutter.Part memoir, part prescriptive handbook, this honest, funny, and heartfelt guide is like a warm soul-baring conversation with your closest and smartest friends.

    Most military thinkers in the years leading up to World War II saw the airplane as an afterthought. But a small band of idealistic strategists, the “Bomber Mafia,” asked: What if precision bombing could cripple the enemy and make war far less lethal? In contrast, the bombing of Tokyo on the deadliest night of the war was the brainchild of General Curtis LeMay, whose brutal pragmatism and scorched-earth tactics in Japan cost thousands of civilian lives, but may have spared even more by averting a planned US invasion. In The Bomber Mafia, Gladwell asks, “Was it worth it?” Things might have gone differently had LeMay’s predecessor, General Haywood Hansell, remained in charge. Hansell believed in precision bombing, but when he and Curtis LeMay squared off for a leadership handover in the jungles of Guam, LeMay emerged victorious, leading to the darkest night of World War II. The Bomber Mafia is a riveting tale of persistence, innovation, and the incalculable wages of war.

    It is an ugly, shameful story of being sold with her mother into slave marriages by Chinese brokers, and although she at first tried to hide the painful details when blending into South Korean society, she realized how her survival story could inspire others. Moreover, her sister had also escaped earlier and had vanished into China for years, prompting the author to go public with her story in the hope of finding her sister.

    Together they spent a combined thirty years in prison before finally being exonerated in 2008. Meanwhile, the real killer remained free.The Cadaver King and the Country Dentist chronicles how the courts and Mississippi's death investigation system--a relic of the Jim Crow era--failed to deliver justice for its citizens and recounts the horrifying story of the two men who built successful careers on the back of this system. For nearly two decades, medical examiner Dr. Steven Hayne performed the vast majority of Mississippi's autopsies, while his friend Dr. Michael West, a local dentist, pitched himself as a forensic jack-of-all-trades. Together they became the go-to experts for prosecutors and helped put countless Mississippians in prison. But then some of those convictions began to fall apart. Radley Balko and Tucker Carrington argue that bad forensics, structural racism, and institutional failures are at fault, and raise sobering questions about our criminal justice system's ability to address them.

    Radiation: What could go wrong? In short, plenty. From Marie Curie carrying around a vial of radium salt because she liked the pretty blue glow to the large-scale disasters at Chernobyl and Fukushima, dating back to the late nineteenth century, nuclear science has had a rich history of innovative exploration and discovery, coupled with mistakes, accidents, and downright disasters. In this lively book, long-time advocate of continued nuclear research and nuclear energy James Mahaffey looks at each incident in turn and analyzes what happened and why, often discovering where scientists went wrong when analyzing past meltdowns. Every incident, while taking its toll, has led to new understanding of the mighty atom—and the fascinating frontier of science that still holds both incredible risk and great promise.

    But how does virality actually work? In The Rules of Contagion, epidemiologist Adam Kucharski explores topics including gun violence, online manipulation, and, of course, outbreaks of disease to show how much we get wrong about contagion, and how astonishing the real science is.Why did the president retweet a Mussolini quote as his own? Why do financial bubbles take off so quickly? And why are disinformation campaigns so effective? By uncovering the crucial factors driving outbreaks, we can see how things really spread -- and what we can do about it.Whether you are an author seeking an audience, a defender of truth, or simply someone interested in human social behavior, The Rules of Contagion is an essential guide to modern life.

    What does it take to run the American supermarket? How do products get to shelves? Who sets the price? And who suffers the consequences of increased convenience and efficiency? In this exposé, author Benjamin Lorr pulls back the curtain on this highly secretive industry. Combining deep sourcing and immersive reporting, Lorr leads a wild investigation in which we learn the secrets of Trader Joe's success from Trader Joe himself, why truckers call their job "sharecropping on wheels," what it takes for a product to earn certification labels like "organic" and "fair trade," the struggles entrepreneurs face as they fight for shelf space, including essential tips, tricks, and traps for any new food business, the truth behind the alarming slave trade in the shrimp industry and much more.

    These vast expanses provide a home to wildlife populations, a vital source of clean air and water, and a haven for recreation.Since its inception, however, America’s public land system has been embroiled in controversy—caught in the push and pull between the desire to develop the valuable resources the land holds or conserve them. Alarmed by rising tensions over the use of these lands, hunter, angler, and outdoor enthusiast Mark Kenyon set out to explore the spaces involved in this heated debate, and learn firsthand how they came to be and what their future might hold.Part travelogue and part historical examination, That Wild Country invites readers on an intimate tour of the wondrous wild and public places that are a uniquely profound and endangered part of the American landscape.

    Eight years later, a schoolteacher who lived four miles away gave birth to a boy whose cherubic smile belied the fast growing tumors that soon riddled his face and chest. The doctors predicted he would not reach his first birthday. They were wrong, but that was only one of many surprises that would eventually come to light in Toms River, culminating in 2001 with a record legal settlement believed to top $35 million and an unprecedented government study confirming the existence of a long-suspected cluster of childhood cancer linked to polluted water and air. A detective story rooted in a scientific quest thousands of years old, Toms River is a tale of dumpers at midnight and deceptions in broad daylight, of corporate avarice and government neglect, and of a few brave individuals who would not keep silent.