In 1996 Joseph LeDoux's "The Emotional Brain" presented a revelatory examination of the biological bases of our emotions and memories. Now, the world-renowned expert on the brain has produced with a groundbreaking work that tells a more profound story: how the little spaces between the neurons-the brain's synapses--are the channels through which we think, act, imagine, feel, and remember. Synapses encode the essence of personality, enabling each of us to function as a distinctive, integrated individual from moment to moment. Exploring the functioning of memory, the synaptic basis of mental illness and drug addiction, and the mechanism of self-awareness, "Synaptic Self" is a provocative and mind-expanding work that is destined to become a classic.

    Complications lays bare a science not in its idealized form but as it actually is--uncertain, perplexing, and profoundly human.Complications is a 2002 National Book Award Finalist for Nonfiction.

    Abel Haggard is an elderly hunchback who haunts the remnants of his family’s farm in the encroaching shadow of the Dallas suburbs, adrift in recollections of those he loved and lost long ago. As a young man, he believed himself to be “the one person too many”; now he is all that remains. Hundreds of miles to the south, in Austin, Seth Waller is a teenage “Master of Nothingness”–a prime specimen of that gangly, pimple-rashed, too-smart breed of adolescent that vanishes in a puff of sarcasm at the slightest threat of human contact. When his mother is diagnosed with a rare form of early-onset Alzheimer’s, Seth sets out on a quest to find her lost relatives and to conduct an “empirical investigation” that will uncover the truth of her genetic history. Though neither knows of the other’s existence, Abel and Seth are linked by a dual legacy: the disease that destroys the memories of those they love, and the story of Isidora–an edenic fantasy world free from the sorrows of remembrance, a land without memory where nothing is ever possessed, so nothing can be lost. Through the fusion of myth, science, and storytelling, this novel offers a dazzling illumination of the hard-learned truth that only through the loss of what we consider precious can we understand the value of what remains.

    But despite the unprecedented attention, our understanding of addiction is trapped in unfounded 20th century ideas, addiction as a crime or as brain disease, and in equally outdated treatment.Challenging both the idea of the addict's "broken brain" and the notion of a simple "addictive personality," The New York Times Bestseller, Unbroken Brain, offers a radical and groundbreaking new perspective, arguing that addictions are learning disorders and shows how seeing the condition this way can untangle our current debates over treatment, prevention and policy. Like autistic traits, addictive behaviors fall on a spectrum -- and they can be a normal response to an extreme situation. By illustrating what addiction is, and is not, the book illustrates how timing, history, family, peers, culture and chemicals come together to create both illness and recovery- and why there is no "addictive personality" or single treatment that works for all.Combining Maia Szalavitz's personal story with a distillation of more than 25 years of science and research, Unbroken Brain provides a paradigm-shifting approach to thinking about addiction.Her writings on radical addiction therapies have been featured in The Washington Post, Vice Magazine, The Wall Street Journal, and The New York Times, in addition to multiple other publications. She has been interviewed about her book on many radio shows including Fresh Air with Terry Gross and The Brian Lehrer show.

    He saved lives, tamed giants. Animals loved him. People loved him. Women loved him (and he loved them back). And he knew more jokes than any man alive.Now, as he lies dying, Edward Bloom can't seem to stop telling jokes -or the tall tales that have made him, in his son's eyes, an extraordinary man. Big Fish is the story of this man's life, told as a series of legends and myths inspired by the few facts his son, William, knows. Through these tales -hilarious and wrenching, tender and outrageous- William begins to understand his elusive father's great feats, and his great failings.

    As psychiatrists, their quest takes them from the squalor of the Victorian lunatic asylum to the crowded lecture halls of the renowned Professor Charcot in Paris; from the heights of the Sierra Madre in California to the plains of unexplored Africa. As the concerns of the old century fade and the First World War divides Europe, the two men's volatile relationship develops and changes, but is always tempered by one exceptional woman; Thomas's sister Sonia. Moving and challenging in equal measure, Human Traces explores the question of what kind of beings men and women really are.'Shocking and enlightening...touching and affecting' Daily Mail

    Residency--and especially the first year, called internship--is legendary for its brutality. Working eighty hours or more per week, most new doctors spend their first year asking themselves why they wanted to be doctors in the first place.Jauhar's internship was even more harrowing than most: he switched from physics to medicine in order to follow a more humane calling--only to find that medicine put patients' concerns last. He struggled to find a place among squadrons of cocky residents and doctors. He challenged the practices of the internship in The New York Times, attracting the suspicions of the medical bureaucracy. Then, suddenly stricken, he became a patient himself--and came to see that today's high-tech, high-pressure medicine can be a humane science after all.Now a thriving cardiologist, Jauhar has all the qualities you'd want in your own doctor: expertise, insight, a feel for the human factor, a sense of humor, and a keen awareness of the worries that we all have in common. His beautifully written memoir explains the inner workings of modern medicine with rare candor and insight. "In Jauhar's wise memoir of his two-year ordeal of doubt and sleep deprivation at a New York hospital, he takes readers to the heart of every young physician's hardest test: to become a doctor yet remain a human being." ― Time

    It’s been three years since his heartthrob, Agnes, wrecked his life with a chat that started, “It’s like that song. ‘If you love somebody, set him free.’” But no matter how much time goes by, Will doesn’t feel very free. He still makes lists of each birthday present Aggi ever gave him, has gymnastic fantasies about a perfect reunion night with her, dwells on the first words she uttered to him.How long can a person stay down in the dumps after being dumped? And how much longer before Will dumps Martina, the sweet but clingy girl he’s seeing? Will anyone ever measure up to his Legendary Girlfriend?Fresh, endearing, and full of humor, My Legendary Girlfriend tells a story that will ring true for everyone who’s ever tried to mend a broken heart.From the Hardcover edition.

    These collectible editions are dressed in the iconic orange and white tri-band cover design, first created in 1935, while french flaps, high-quality paper, and striking cover illustrations provide the cutting-edge design treatment that is the signature of Penguin Classics Deluxe Editions today. White Noise Winner of the 1985 National Book Award, White Noise tells the story of Jack Gladney, his fourth wife, Babette, and their four ultramodern offspring, as they navigate the rocky passages of family life to the background babble of brand-name consumerism.

    Discusses the causes, symptoms, and treatment of attention-deficit Disorder (ADD).

    She shows how the stalling of early twentieth century efforts in this direction allowed Freudians and social scientists to insist, with some justification, that they had better ways of analyzing and fixing minds.But when the Freudians overreached, they drove psychiatry into a state of crisis that a new “biological revolution” was meant to alleviate. Harrington shows how little that biological revolution had to do with breakthroughs in science, and why the field has fallen into a state of crisis in our own time.Mind Fixers makes clear that psychiatry’s waxing and waning biological enthusiasms have been shaped not just by developments in the clinic and lab, but also by a surprising range of social factors, including immigration, warfare, grassroots activism, and assumptions about race and gender. Government programs designed to empty the state mental hospitals, acrid rivalries between different factions in the field, industry profit mongering, consumerism, and an uncritical media have all contributed to the story as well.In focusing particularly on the search for the biological roots of schizophrenia, depression, and bipolar disorder, Harrington underscores the high human stakes for the millions of people who have sought medical answers for their mental suffering. This is not just a story about doctors and scientists, but about countless ordinary people and their loved ones.A clear-eyed, evenhanded, and yet passionate tour de force, Mind Fixers recounts the past and present struggle to make mental illness a biological problem in order to lay the groundwork for creating a better future, both for those who suffer and for those whose job it is to care for them.

    Today he is the director of the Center for Compassion and Altruism Research and Education (CCARE) at Stanford University, of which the Dalai Lama is a founding benefactor. But back then his life was at a dead end until at twelve he wandered into a magic shop looking for a plastic thumb. Instead he met Ruth, a woman who taught him a series of exercises to ease his own suffering and manifest his greatest desires. Her final mandate was that he keep his heart open and teach these techniques to others. She gave him his first glimpse of the unique relationship between the brain and the heart.Doty would go on to put Ruth’s practices to work with extraordinary results—power and wealth that he could only imagine as a twelve-year-old, riding his orange Sting-Ray bike. But he neglects Ruth’s most important lesson, to keep his heart open, with disastrous results—until he has the opportunity to make a spectacular charitable contribution that will virtually ruin him. Part memoir, part science, part inspiration, and part practical instruction, Into the Magic Shop shows us how we can fundamentally change our lives by first changing our brains and our hearts.

    One that looks human and exemplifies the ideal world he comes from, a world free from human nature's greed and cruelty. That creature would be "prot", as he calls himself, the newest patient at the Manhattan Psychiatric Institute.Prot seems to know more than he should about faster-than-the-speed-of-light-travel. And besides drawing constellations as viewed from K-PAX, the name of his home planet, "prot" can describe its orbit around double suns in unpublished detail. Who is "prot" and where did he really come from? Why does he have the ability to cure severe mental cases? And to disappear at will? And to charm everyone he comes into contact with?Bizarre delusion or reality? Listen in as a psychiatrist who specializes in delusional behavior documents his sessions with the man from K-PAX.(P)2004 Brilliance Audio, Inc.

    Their stainless-steel kitchen is newly installed, and their Mercedes is parked curbside. After Sophie is bitten on the hand while trying to feed a stray, perhaps rabies-infected cat, a series of small and ominous disasters begin to plague the Bentwoods' lives, revealing the fault lines and fractures in a marriage—and a society—wrenching itself apart.First published in 1970 to wide acclaim, Desperate Characters stands as one of the most dazzling and rigorous examples of the storyteller's craft in postwar American literature — a novel that, according to Irving Howe, ranks with "Billy Budd, The Great Gatsby, Miss Lonelyhearts, and Seize the Day."

    He is a man who can count all his friends on the fingers of one hand, whose lifelong difficulty with social rituals has convinced him that he is simply not wired for romance. So when an acquaintance informs him that he would make a “wonderful” husband, his first reaction is shock. Yet he must concede to the statistical probability that there is someone for everyone, and he embarks upon The Wife Project. In the orderly, evidence-based manner with which he approaches all things, Don sets out to find the perfect partner. She will be punctual and logical—most definitely not a barmaid, a smoker, a drinker, or a late-arriver.Yet Rosie Jarman is all these things. She is also beguiling, fiery, intelligent—and on a quest of her own. She is looking for her biological father, a search that a certain DNA expert might be able to help her with. Don's Wife Project takes a back burner to the Father Project and an unlikely relationship blooms, forcing the scientifically minded geneticist to confront the spontaneous whirlwind that is Rosie—and the realization that love is not always what looks good on paper.The Rosie Project is a moving and hilarious novel for anyone who has ever tenaciously gone after life or love in the face of overwhelming challenges.