That's a lot to pin on a simple molecule.But your testosterone level doesn't actually predict your competitive drive, appetite for risk, sex drive, strength, or athletic prowess. It isn't the biological essence of manliness--in fact, it isn't even a male sex hormone. So what is it, and how did we come to endow it with such superhuman powers? This unauthorized biography pries the much-maligned T free from over a century of misconceptions.Testosterone's story begins long before the hormone was even isolated, when scientists first went looking for the chemical essence of masculinity. Over time, this molecule provided a handy rationale for countless behaviors--from the boorish to the enviable. Today, as competitive athletes turn to testosterone for competitive advantage, and we continue to debate what it means to be a man or woman, it is back in the news again. What we think we know about has stood in the way of an accurate understanding of its surprising functions and effects. Rebecca Jordan-Young and Katrina Karkazis focus on what testosterone does in six domains: reproduction, aggression, risk-taking, power, sports, and parenting. and let us us see the real testosterone for the first time.

    While young gay men often come out more readily, even those from the most progressive of backgrounds still struggle with the legacy of early-life stigma and a deficit of self-acceptance, which can fuel doubt, regret, and, at worst, self-loathing. And this is to say nothing of the ongoing trauma wrought by AIDS, which is all too often relegated to history. Drawing on his work as a clinical psychologist during and in the aftermath of the epidemic, Walt Odets reflects on what it means to survive and figure out a way to live in a new, uncompromising future, both for the men who endured the upheaval of those years and for the younger men who have come of age since then, at a time when an HIV epidemic is still ravaging the gay community, especially among the most marginalized.Through moving stories—of friends and patients, and his own—Odets considers how experiences early in life launch men on trajectories aimed at futures that are not authentically theirs. He writes to help reconstruct how we think about gay life by considering everything from the misleading idea of “the homosexual,” to the diversity and richness of gay relationships, to the historical role of stigma and shame and the significance of youth and of aging. Crawling out from under the trauma of destructive early-life experience and the two epidemics, and into a century of shifting social values, provides an opportunity to explore possibilities rather than live with limitations imposed by others. Though it is drawn from decades of private practice, activism, and life in the gay community, Odets’s work achieves remarkable universality. At its core, Out of the Shadows is driven by his belief that it is time that we act based on who we are and not who others are or who they would want us to be. We—particularly the young—must construct our own paths through life. Out of the Shadows is a necessary, impassioned argument for how and why we must all take hold of our futures.

    The flamboyantly dressed Miss Fanny Park and Miss Stella Boulton are causing a stir in the Strand Theatre. All eyes are riveted upon their lascivious oglings of the gentlemen in the stalls. Moments later they are led away by the police. What followed was a scandal that shocked and titillated Victorian England in equal measure. It turned out that the alluring Miss Fanny Park and Miss Stella Boulton were no ordinary young women. Far from it. In fact, they were young men who liked to dress as women. When the Metropolitan Police launched a secret campaign to bring about their downfall, they were arrested and subjected to a sensational show trial in Westminster Hall. As the trial of 'the Young Men in Women's Clothes' unfolded, Fanny and Stella's extraordinary lives as wives and daughters, actresses and whores were revealed to an incredulous public. With a cast of peers, politicians and prostitutes, drag queens, doctors and detectives, "Fanny and Stella" is a Victorian peepshow, exposing the startling underbelly of nineteenth-century London. By turns tragic and comic, meticulously researched and dazzlingly written, "Fanny and Stella" is an enthralling tour-de-force.

    . . Peter Staley has written an electrifying primer for anyone who’s thinking/worrying/wondering about how to change/save the world.” —Tony Kushner, Pulitzer Prize–winning playwright of Angels in AmericaThe previously untold stories of the life of the leading subject in David France’s How To Survive A Plague, Peter Staley, including his continuing activism In 1987, somebody shoved a flyer into the hand of Peter Staley: massive AIDS demonstration, it announced. After four years on Wall Street as a closeted gay man, Staley was familiar with the homophobia common on trading floors. He also knew that he was not beyond the reach of HIV, having recently been diagnosed with AIDS-Related Complex. A week after the protest, Staley found his way to a packed meeting of the AIDS Coalition To Unleash Power—ACT UP—in the West Village. It would prove to be the best decision he ever made. ACT UP would change the course of AIDS, pressuring the National Institutes of Health, the FDA, and three administrations to finally respond with research that ultimately saved millions of lives. Staley, a shrewd strategist with nerves of steel, organized some of the group’s most spectacular actions, from shutting down trading on the floor of the New York Stock Exchange to putting a giant condom over the house of Senator Jesse Helms. Never Silent is the inside story of what brought Staley to ACT UP and the explosive and sometimes painful years to follow—years filled with triumph, humiliation, joy, loss, and persistence.Never Silent is guaranteed to inspire the activist within all of us.

    Taking Turns pulls back the curtain on life in the ward.A shining example of excellence in the treatment and care of patients, Unit 371 was a community for thousands of patients and families affected by HIV and AIDS and the people who cared for them. This graphic novel combines Czerwiec’s memories with the oral histories of patients, family members, and staff. It depicts life and death in the ward, the ways the unit affected and informed those who passed through it, and how many look back on their time there today. Czerwiec joined Unit 371 at a pivotal time in the history of AIDS: deaths from the syndrome in the Midwest peaked in 1995 and then dropped drastically in the following years, with the release of antiretroviral protease inhibitors. This positive turn of events led to a decline in patient populations and, ultimately, to the closure of Unit 371. Czerwiec’s restrained, inviting drawing style and carefully considered narrative examine individual, institutional, and community responses to the AIDS epidemic—as well as the role that art can play in the grieving process.Deeply personal yet made up of many voices, this history of daily life in a unique AIDS care unit is an open, honest look at suffering, grief, and hope among a community of medical professionals and patients at the heart of the epidemic.

     But throughout a long and distinguished career an air of secrecy, even of scandal, always clung to Barry. The shrill voice, the diminutive build, the almost ostentatious humanity – all struck a discordant note in the stiff, conventional world of the officers’ mess. Only after the doctor’s death in 1865 did the incredible truth come to light: Dr. James Barry was a woman. What was her real identity? How did she manage to conceal her sex from the army for forty-six years? Why did she take on a man’s role and a man’s work? In this vivid and meticulous biography, June Rose pieces together the clues in the Barry mystery and comes up with some astonishing answers. She tells of the elite intellectual circle which first conceived the masquerade and sponsored the little girl’s entrance, in disguise, into Edinburgh University; she recounts Barry’s strange connection with a powerful aristocratic family and her intense relationship with Lord Charles Somerset, Governor of the Cape Colony and one of the few men to know her secret. And, most fascinating of all, she provides rare insights into Barry’s unique and contradictory personality: her determined clashes with authority, her courageous endurance of appalling conditions in every corner of the globe, her unforgettable encounter with Florence Nightingale. The Perfect Gentleman is the story of an extraordinary adventure – and a remarkable woman. Praise for June Rose ‘A fascinating, well-documented book’ - Sunday Telegraph ‘June Rose has succeeded in re-creating the past and relating it to the present... a fascinating account’ - Times Literary Supplement June Rose (1926-2018) was a writer and broadcaster who specialised in probing into the human and historical background of the social issues of the day. She authored several biographies, including Marie Stopes and the Sexual Revolution, Elizabeth Fry, the nineteenth-century prison reformer and Modigliani, the twentieth-century Italian painter and Susan Valadon: Mistress of Montmartre.

    Features a new chapter and afterward on recent biological breakthroughs.

    The age-old disease spread swiftly through an increasingly interconnected American landscape: from southern tobacco plantations to the dense immigrant neighborhoods of northern cities to far-flung villages on the edges of the nascent American empire. In Pox, award-winning historian Michael Willrich offers a gripping chronicle of how the nation's continentwide fight against smallpox launched one of the most important civil liberties struggles of the twentieth century.At the dawn of the activist Progressive era and during a moment of great optimism about modern medicine, the government responded to the deadly epidemic by calling for universal compulsory vaccination. To enforce the law, public health authorities relied on quarantines, pesthouses, and "virus squads"-corps of doctors and club-wielding police. Though these measures eventually contained the disease, they also sparked a wave of popular resistance among Americans who perceived them as a threat to their health and to their rights.At the time, anti-vaccinationists were often dismissed as misguided cranks, but Willrich argues that they belonged to a wider legacy of American dissent that attended the rise of an increasingly powerful government. While a well-organized anti-vaccination movement sprang up during these years, many Americans resisted in subtler ways-by concealing sick family members or forging immunization certificates. Pox introduces us to memorable characters on both sides of the debate, from Henning Jacobson, a Swedish Lutheran minister whose battle against vaccination went all the way to the Supreme Court, to C. P. Wertenbaker, a federal surgeon who saw himself as a medical missionary combating a deadly-and preventable-disease.As Willrich suggests, many of the questions first raised by the Progressive-era antivaccination movement are still with us: How far should the government go to protect us from peril? What happens when the interests of public health collide with religious beliefs and personal conscience? In Pox, Willrich delivers a riveting tale about the clash of modern medicine, civil liberties, and government power at the turn of the last century that resonates powerfully today.

    Chapters cover the transsexual and transvestite communities in the years following World War II; trans radicalism and social change, which spanned from 1966 with the publication of The Transsexual Phenomenon, and lasted through the early 1970s; the mid-'70s to 1990-the era of identity politics and the changes witnessed in trans circles through these years; and the gender issues witnessed through the '90s and '00s. Transgender History includes informative sidebars highlighting quotes from major texts and speeches in transgender history and brief biographies of key players, plus excerpts from transgender memoirs and discussion of treatments of transgenderism in popular culture.

    

    But in the inevitable condition of aging and death, the goals of medicine seem too frequently to run counter to the interest of the human spirit. Nursing homes, preoccupied with safety, pin patients into railed beds and wheelchairs. Hospitals isolate the dying, checking for vital signs long after the goals of cure have become moot. Doctors, committed to extending life, continue to carry out devastating procedures that in the end extend suffering.Gawande, a practicing surgeon, addresses his profession's ultimate limitation, arguing that quality of life is the desired goal for patients and families. Gawande offers examples of freer, more socially fulfilling models for assisting the infirm and dependent elderly, and he explores the varieties of hospice care to demonstrate that a person's last weeks or months may be rich and dignified.

    In July 1518 a terrifying and mysterious plague struck the medieval city of Strasbourg. Hundreds of men and women danced wildly, day after day, in the punishing summer heat. They did not want to dance, but could not stop. Throughout August and early September more and more were seized by the same terrible compulsion. By the time the epidemic subsided, heat and exhaustion had claimed an untold number of lives, leaving thousands bewildered and bereaved, and an enduring enigma for future generations. Drawing on fresh evidence, John Waller's account of the bizarre events of 1518 explains why Strasbourg's dancing plague took place. In doing so it leads us into a largely vanished world, evoking the sights, sounds, aromas, diseases and hardships, the fervent supernaturalism, and the desperate hedonism of the late medieval world. At the same time, the extraordinary story this book tells offers rich insights into how people behave when driven beyond the limits of endurance. Above all, this is an exploration into the strangest capabilities of the human mind and the extremes to which fear and irrationality can lead us.

    Every day the staff of emergency rooms throughout the world are saving lives - 24/7/365. Dr. Patrick Crocker provides us an intimate glimpse into the growing mind of an emergency physician, from residency to retirement. Told in a unique first-person stream of consciousness style, you are right in the middle of the action, looking over the doctor's shoulder while he works. In this compilation of notable, frightening, funny, sad, and poignant cases, you'll see Dr. Crocker's struggles to Do No Harm in the most challenging of situations. Through these stories, you'll see him find the delicate balance between help and harm, empathy and self-preservatio

    By allowing women to control their fertility, the birth control pill has revolutionized women's lives. Women are going to college, graduating, and entering the workforce in greater numbers than ever before, and there's good reason to believe that the birth control pill has a lot to do with this. But there's a lot more to the pill than meets the eye.Although women go on the pill for a small handful of targeted effects (pregnancy prevention and clearer skin, yay!), sex hormones can't work that way. Sex hormones impact the activities of billions of cells in the body at once, many of which are in the brain. There, they play a role in influencing attraction, sexual motivation, stress, hunger, eating patterns, emotion regulation, friendships, aggression, mood, learning, and more. This means that being on the birth control pill makes women a different version of themselves than when they are off of it. And this is a big deal. For instance, women on the pill have a dampened cortisol spike in response to stress. While this might sound great (no stress!), it can have negative implications for learning, memory, and mood. Additionally, because the pill influences who women are attracted to, being on the pill may inadvertently influence who women choose as partners, which can have important implications for their relationships once they go off it. Sometimes these changes are for the better . . . but other times, they're for the worse. By changing what women's brains do, the pill also has the ability to have cascading effects on everything and everyone that a woman encounters. This means that the reach of the pill extends far beyond women's own bodies, having a major impact on society and the world.This paradigm-shattering book provides an even-handed, science-based understanding of who women are, both on and off the pill. It will change the way that women think about their hormones and how they view themselves. It also serves as a rallying cry for women to demand more information from science about how their bodies and brains work and to advocate for better research. This book will help women make more informed decisions about their health, whether they're on the pill or off of it.

    While detailing the history of vaccine invention, Kinch reveals the ominous reality that our victories against vaccine-preventable diseases are not permanent—and could easily be undone. In the tradition of John Barry’s The Great Influenza and Siddhartha Mukherjee’s The Emperor of All Maladies, Between Hope and Fear relates the remarkable intersection of science, technology and disease that has helped eradicate many of the deadliest plagues known to man.