These “psychosurgeons,” as they called themselves, occupied a gray zone between medical research and medical practice, and ended up subjecting untold numbers of people to the types of surgical experiments once limited to chimpanzees.The most important test subject to emerge from this largely untold chapter in American history was a twenty-seven-year-old factory worker named Henry Molaison. In 1953, Henry—who suffered from severe epilepsy—received a radical new version of the lobotomy, one that targeted the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry left the operating room profoundly amnesic, unable to create new long-term memories. Over the next sixty years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.Luke Dittrich uses the case of Patient H.M. as a starting point for a kaleidoscopic journey, one that moves from the first recorded brain surgeries in ancient Egypt to the cutting-edge laboratories of MIT. He takes readers inside the old asylums and operating theaters where psychosurgeons conducted their human experiments, and behind the scenes of a bitter custody battle over the ownership of the most important brain in the world. Throughout, Dittrich delves into the enduring mysteries of the mind while exposing troubling stories of just how far we’ve gone in our pursuit of knowledge. It is also, at times, a deeply personal journey. Dittrich’s grandfather was the brilliant, morally complex surgeon who operated on Molaison—and thousands of other patients. The author’s investigation into the dark roots of modern memory science ultimately forces him to confront unsettling secrets in his own family history, and to reveal the tragedy that fueled his grandfather’s relentless experimentation—experimentation that would revolutionize our understanding of ourselves.Patient H.M. combines the best of biography, memoir, and science journalism to create a haunting, endlessly fascinating story, one that reveals the wondrous and devastating things that can happen when hubris, ambition, and human imperfection collide.

    Delving into brand-new research, she uncovers the powers of the natural world to improve health, promote reflection and innovation, and strengthen our relationships. As our modern lives shift dramatically indoors, these ideas—and the answers they yield—are more urgent than ever.

    It intersects with Darwin’s theory of evolution, and collides with the horrors of Nazi eugenics in the 1940s. The gene transforms post-war biology. It reorganizes our understanding of sexuality, temperament, choice and free will. This is a story driven by human ingenuity and obsessive minds – from Charles Darwin and Gregor Mendel to Francis Crick, James Watson and Rosalind Franklin, and the thousands of scientists still working to understand the code of codes.This is an epic, moving history of a scientific idea coming to life, by the author of The Emperor of All Maladies. But woven through The Gene, like a red line, is also an intimate history – the story of Mukherjee’s own family and its recurring pattern of mental illness, reminding us that genetics is vitally relevant to everyday lives. These concerns reverberate even more urgently today as we learn to “read” and “write” the human genome – unleashing the potential to change the fates and identities of our children.Majestic in its ambition, and unflinching in its honesty, The Gene gives us a definitive account of the fundamental unit of heredity – and a vision of both humanity’s past and future.

    Whether pondering black holes or predicting discoveries at CERN, physicists believe the best theories are beautiful, natural, and elegant, and this standard separates popular theories from disposable ones. This is why, Sabine Hossenfelder argues, we have not seen a major breakthrough in the foundations of physics for more than four decades. The belief in beauty has become so dogmatic that it now conflicts with scientific objectivity: observation has been unable to confirm mindboggling theories, like supersymmetry or grand unification, invented by physicists based on aesthetic criteria. Worse, these "too good to not be true" theories are actually untestable and they have left the field in a cul-de-sac. To escape, physicists must rethink their methods. Only by embracing reality as it is can science discover the truth.

    She was married with children and a good career. So why did she feel miserable? And why did it seem that other Generation X women were miserable, too?Calhoun decided to find some answers. She looked into housing costs, HR trends, credit card debt averages, and divorce data. At every turn, she saw a pattern: sandwiched between the Boomers and the Millennials, Gen X women were facing new problems as they entered middle age, problems that were being largely overlooked.Speaking with women across America about their experiences as the generation raised to “have it all,” Calhoun found that most were exhausted, terrified about money, under-employed, and overwhelmed. Instead of being heard, they were told instead to lean in, take “me-time,” or make a chore chart to get their lives and homes in order.In Why We Can’t Sleep, Calhoun opens up the cultural and political contexts of Gen X’s predicament and offers solutions for how to pull oneself out of the abyss—and keep the next generation of women from falling in. The result is reassuring, empowering, and essential reading for all middle-aged women, and anyone who hopes to understand them.

    But, Alex Bellos says, "math can be inspiring and brilliantly creative. Mathematical thought is one of the great achievements of the human race, and arguably the foundation of all human progress. The world of mathematics is a remarkable place."Bellos has traveled all around the globe and has plunged into history to uncover fascinating stories of mathematical achievement, from the breakthroughs of Euclid, the greatest mathematician of all time, to the creations of the Zen master of origami, one of the hottest areas of mathematical work today. Taking us into the wilds of the Amazon, he tells the story of a tribe there who can count only to five and reports on the latest findings about the math instinct--including the revelation that ants can actually count how many steps they've taken. Journeying to the Bay of Bengal, he interviews a Hindu sage about the brilliant mathematical insights of the Buddha, while in Japan he visits the godfather of Sudoku and introduces the brainteasing delights of mathematical games.Exploring the mysteries of randomness, he explains why it is impossible for our iPods to truly randomly select songs. In probing the many intrigues of that most beloved of numbers, pi, he visits with two brothers so obsessed with the elusive number that they built a supercomputer in their Manhattan apartment to study it. Throughout, the journey is enhanced with a wealth of intriguing illustrations, such as of the clever puzzles known as tangrams and the crochet creation of an American math professor who suddenly realized one day that she could knit a representation of higher dimensional space that no one had been able to visualize. Whether writing about how algebra solved Swedish traffic problems, visiting the Mental Calculation World Cup to disclose the secrets of lightning calculation, or exploring the links between pineapples and beautiful teeth, Bellos is a wonderfully engaging guide who never fails to delight even as he edifies. "Here's Looking at Euclid "is a rare gem that brings the beauty of math to life.

    Radiation: What could go wrong? In short, plenty. From Marie Curie carrying around a vial of radium salt because she liked the pretty blue glow to the large-scale disasters at Chernobyl and Fukushima, dating back to the late nineteenth century, nuclear science has had a rich history of innovative exploration and discovery, coupled with mistakes, accidents, and downright disasters. In this lively book, long-time advocate of continued nuclear research and nuclear energy James Mahaffey looks at each incident in turn and analyzes what happened and why, often discovering where scientists went wrong when analyzing past meltdowns. Every incident, while taking its toll, has led to new understanding of the mighty atom—and the fascinating frontier of science that still holds both incredible risk and great promise.

    . . and possibly change the world.Andy Bramante left his successful career as a corporate scientist to teach public high school--and now helms one of the most remarkable classrooms in America. Bramante's unconventional class at Connecticut's prestigious yet diverse Greenwich High School has no curriculum, tests, textbooks, or lectures, and is equal parts elite research lab, student counseling office, and teenage hangout spot. United by a passion to learn, Mr. B.'s band of whiz kids set out every year to conquer the brutally competitive science fair circuit. They have won the top prize at the Google Science Fair, made discoveries that eluded scientists three times their age, and been invited to the Nobel Prize ceremony in Stockholm.A former Emmy-winning producer for CBS News, Heather Won Tesoriero embeds in this dynamic class to bring Andy and his gifted, all-too-human kids to life--including William, a prodigy so driven that he's trying to invent diagnostics for artery blockage and Alzheimer's (but can't quite figure out how to order a bagel); Ethan, who essentially outgrows high school in his junior year and founds his own company to commercialize a discovery he made in the class; Sophia, a Lyme disease patient whose ambitious work is dedicated to curing her own debilitating ailment; Romano, a football player who hangs up his helmet to pursue his secret science expertise and develop a "smart" liquid bandage; and Olivia, whose invention of a fast test for Ebola brought her science fair fame and an appearance on The Late Show with Stephen Colbert.We experience the thrill of discovery, the heartbreak of failed endeavors, and perhaps the ultimate high: a yes from Harvard. Moving, funny, and utterly engrossing, The Class is a superb account of hard work and high spirits, a stirring tribute to how essential science is in our schools and our lives, and a heartfelt testament to the power of a great teacher to help kids realize their unlimited potential.

    In three successive waves, from 1918 to 1919, influenza killed more than 50 million people. German soldiers termed it Blitzkatarrh, British soldiers referred to it as Flanders Grippe, but world-wide, the pandemic gained the notorious title of “Spanish Flu." Nowhere on earth escaped: the United States recorded 550,000 deaths (five times its total military fatalities in the war), while European deaths totaled more than two million.Amid the war, some governments suppressed news of the outbreak. Even as entire battalions were decimated, with both the Allies and the Germans suffering massive casualties, the details of many servicemen’s deaths were hidden to protect public morale. Meanwhile, civilian families were being struck down in their homes. Philadelphia ran out of gravediggers and coffins, and mass burial trenches had to be excavated with steam shovels. Spanish flu conjured up the specter of the Black Death of 1348 and the great plague of 1665, while the medical profession, shattered after five terrible years of conflict, lacked the resources to contain and defeat this new enemy. Through primary and archival sources, historian Catharine Arnold gives readers the first truly global account of this terrible epidemic.

    So do our politicians.We're not listening.And no one is listening to us.Despite living in a world where technology allows constant digital communication and opportunities to connect, it seems no one is really listening or even knows how. And it’s making us lonelier, more isolated, and less tolerant than ever before. A listener by trade, New York Times contributor Kate Murphy wanted to know how we got here.In this always illuminating and often humorous deep dive, Murphy explains why we’re not listening, what it’s doing to us, and how we can reverse the trend. She makes accessible the psychology, neuroscience, and sociology of listening while also introducing us to some of the best listeners out there (including a CIA agent, focus group moderator, bartender, radio producer, and top furniture salesman). It’s time to stop talking and start listening.

    Joe, Florida and confessed that he’d shot and killed his parents in their family home in Silver Spring, Maryland. He said he’d been possessed by the devil. He was eventually diagnosed with schizophrenia and ruled “not criminally responsible” for the murders on grounds of insanity.But after the trial, where do the "criminally insane" go? Brottman reveals Brian's inner life leading up to the murder, as well as his complicated afterlife in a maximum security psychiatric hospital, where he is neither imprisoned nor free. During his 27 years at the hospital, Brian has tried to escape and been shot by police, and has witnessed three patient-on-patient murders. He’s experienced the drugging of patients beyond recognition, a sadistic system of rewards and punishments, and the short-lived reign of a crazed psychiatrist-turned-stalker. In the tradition of One Flew Over The Cuckoo’s Nest, Couple Found Slain is an insider’s account of life in the underworld of forensic psych wards in America and the forgotten lives of those held there, often indefinitely.

    . . and then broke? How would you survive? Could you improve on humanity's original timeline? And how hard would it be to domesticate a giant wombat? With this book as your guide, you'll survive--and thrive--in any period in Earth's history. Bestselling author and time-travel enthusiast Ryan North shows you how to invent all the modern conveniences we take for granted--from first principles. This illustrated manual contains all the science, engineering, art, philosophy, facts, and figures required for even the most clueless time traveler to build a civilization from the ground up. Deeply researched, irreverent, and significantly more fun than being eaten by a saber-toothed tiger, How to Invent Everything will make you smarter, more competent, and completely prepared to become the most important and influential person ever.

    Before the trip’s end, she develops psychosis. In desperation, her husband admits her to a nearby psychiatric hospital, where she begins the hard work of rebuilding her identity.In this memoir Catherine reconstructs her sense of self, starting with her childhood as the daughter of Korean immigrants, moving through a traumatic past relationship, and on to the early years of her courtship with and marriage to her husband, James. She interweaves these parts of her past with an immediate recounting of the days she spent in the ward.

    Forced to remain inside until they'd "proven" themselves sane, all eight emerged with alarming diagnoses and even more troubling stories of their treatment. Rosenhan's study broke open the field of psychiatry, closing down institutions and changing mental health diagnosis forever. But, as Cahalan's new research shows, very little in this saga is exactly as it seems. What really happened behind those closed asylum doors, and what does it mean for our understanding of mental illness today?

    The Green Book listed hotels, restaurants, gas stations, and other businesses that were safe for black travelers. It was a resourceful and innovative solution to a horrific problem. It took courage to be listed in the Green Book, and Overground Railroad celebrates the stories of those who put their names in the book and stood up against segregation. It shows the history of the Green Book, how we arrived at our present historical moment, and how far we still have to go when it comes to race relations in America.