Euan Ashley, Stanford professor of medicine and genetics, brings the breakthroughs of precision medicine to vivid life through the real diagnostic journeys of his patients and the tireless efforts of his fellow doctors and scientists as they hunt to prevent, predict, and beat disease.Since the Human Genome Project was completed in 2003, the price of genome sequencing has dropped at a staggering rate. It’s as if the price of a Ferrari went from $350,000 to a mere forty cents. Through breakthroughs made by Dr. Ashley’s team at Stanford and other dedicated groups around the world, analyzing the human genome has decreased from a heroic multibillion dollar effort to a single clinical test costing less than $1,000. For the first time we have within our grasp the ability to predict our genetic future, to diagnose and prevent disease before it begins, and to decode what it really means to be human.In The Genome Odyssey, Dr. Ashley details the medicine behind genome sequencing with clarity and accessibility. More than that, with passion for his subject and compassion for his patients, he introduces readers to the dynamic group of researchers and doctor detectives who hunt for answers, and to the pioneering patients who open up their lives to the medical community during their search for diagnoses and cures. He describes how he led the team that was the first to analyze and interpret a complete human genome, how they broke genome speed records to diagnose and treat a newborn baby girl whose heart stopped five times on the first day of her life, and how they found a boy with tumors growing inside his heart and traced the cause to a missing piece of his genome.These patients inspire Dr. Ashley and his team as they work to expand the boundaries of our medical capabilities and to envision a future where genome sequencing is available for all, where medicine can be tailored to treat specific diseases and to decode pathogens like viruses at the genomic level, and where our medical system as we know it has been completely revolutionized.

    How they got here, persevered, and ultimately thrived is a story that resonates from the Pleistocene to our modern era. The lower sea levels of the Ice Age exposed a vast land bridge between Asia and North America, but the land bridge was not the only way across. Different people arrived from different directions, and not all at the same time.The first explorers of the New World were few, their encampments fleeting. The continent they reached had no people but was inhabited by megafauna--mastodons, giant bears, mammoths, saber-toothed cats, five-hundred-pound panthers, enormous bison, and sloths that stood one story tall. The first people were hunters--Paleolithic spear points are still encrusted with the proteins of their prey--but they were wildly outnumbered and many would themselves have been prey to the much larger animals.Atlas of a Lost World chronicles the last millennia of the Ice Age, the violent oscillations and retreat of glaciers, the clues and traces that document the first encounters of early humans, and the animals whose presence governed the humans' chances for survival. A blend of science and personal narrative reveals how much has changed since the time of mammoth hunters, and how little. Across unexplored landscapes yet to be peopled, readers will see the Ice Age, and their own age, in a whole new light.

    Explains the basics of orthomolecular medicine, plus megavitamin therapy for arthritis, cancer, behavioral problems, and more.

    Unlocking the secrets of our genomes opens the door to understanding why we are the way we are and potentially fixing what ails us, from cancer and diabetes to obesity and male pattern baldness. But what exactly will happen to this information? Will it be a boon or just another marketing tool?Here Is a Human Being is the first in-depth look at personal genomics—its larger-than-life research subjects; its entrepreneurs and do-it-yourselfers; its technology developers; and the bewildered physicians and regulators who must negotiate with it—and what it means to be a “public genome” in a world where privacy is already under siege.

    But what if science itself can’t be relied on?Medicine, education, psychology, health, parenting – wherever it really matters, we look to science for advice. Science Fictions reveals the disturbing flaws that undermine our understanding of all of these fields and more.While the scientific method will always be our best and only way of knowing about the world, in reality the current system of funding and publishing science not only fails to safeguard against scientists’ inescapable biases and foibles, it actively encourages them. From widely accepted theories about ‘priming’ and ‘growth mindset’ to claims about genetics, sleep, microbiotics, as well as a host of drugs, allergies and therapies, we can trace the effects of unreliable, overhyped and even fraudulent papers in austerity economics, the anti-vaccination movement and dozens of bestselling books – and occasionally count the cost in human lives.Stuart Ritchie was among the first people to help expose these problems. In this vital investigation, he gathers together the evidence of their full and shocking extent – and how a new reform movement within science is fighting back. Often witty yet deadly serious, Science Fictions is at the vanguard of the insurgency, proposing a host of remedies to save and protect this most valuable of human endeavours from itself.

    government’s Human Genome Project. Venter hoped that by decoding the genome ahead of schedule, he would speed up the pace of biomedical research and save the lives of thousands of people. He also hoped to become very famous and very rich. Calling his company Celera (from the Latin for “speed”), he assembled a small group of scientists in an empty building in Rockville, Maryland, and set to work.At the same time, the leaders of the government program, under the direction of Francis Collins, head of the National Human Genome Research Institute at the National Institutes of Health, began to mobilize an unexpectedly unified effort to beat Venter to the prize—knowledge that had the potential to revolutionize medicine and society. The stage was set for one of the most thrilling—and important—dramas in the history of science. The Genome War is the definitive account of that drama—the race for the greatest prize biology has had to offer, told by a writer with exclusive access to Venter’s operation from start to finish. It is also the story of how one man’s ambition created a scientific Camelot where, for a moment, it seemed that the competing interests of pure science and commercial profit might be gloriously reconciled—and the national repercussions that resulted when that dream went awry.From the Hardcover edition.

    So who better than an alien to explain it all? Enter Bloort 183, a scientist from an asexual alien race threatened by disease, who's been charged with researching the fundamentals of human DNA and evolution and laying it all out in clear, simple language so that even his slow-to-grasp-the-point leader can get it. In the hands of the award-winning writer Mark Schultz, Bloort's predicament becomes the means of giving even the most science-phobic reader a complete introduction to the history and science of genetics that's as easy to understand as it is entertaining to read.

    A defiant atheist, Chapman is confronted not only by the fundamentalist beliefs that continue to banish the theory of evolution but by his own spiritual malaise as the outward journey becomes an inward quest, a tragicomic "accidental memoir"."First there was Charles Darwin, two yards long and nobody's fool. Then there was his son, my great-grandfather, Sir Francis Darwin, an eminent botanist. Then came my grandmother Frances, a modest poet who spent a considerable amount of time in rest-homes for depression From her issued my beloved mother, Clare, who was extremely short, failed to complete medical school, and eventually became an alcoholic. Then we get down to me. I'm in the movie business."Trials of the Monkey combines travel writing and reportage, as Chapman records his encounters in the South, with history and the accidental memoir of a man full of mid-life doubts in a genre-breaking first book that is darkly funny, provocative and poignant.

    De Waal reminds readers through his account of the chimps' sexual rivalries and coalitions, and intelligent rather than instinctual actions, that the roots of politics are older than humanity.

    Using this example as a springboard, David M. Raup leaps into an egaging discussion of the theories, assumptions, and difficulties associated with the science of species extinction. Woven is along the way are stories of the trilobite eye, tropical reefs, flying reptiles, and the fate of the heath hen on Martha's Vineyard, a very modern extinction.

    The first is the astonishing achievement of the Human Genome Project, which, it was anticipated, would identify the genetic basis of those characteristics that distinguish humans from their primate cousins. The second is the phenomenal advance in brain imaging that now permits neuroscientists to observe the brain 'in action' and thus account for the remarkable properties of the human mind.But that is not how it has turned out. It is simply not possible to get from the monotonous sequence of genes along the Double Helix to the near infinite diversity of the living world, nor to translate the electrical firing of the brain into the creativity of the human mind. This is not a matter of not knowing all the facts. Rather, science has inadvertently discovered that its theories are insufficient to conjure the wonder of the human experience from the bare bones of our genes and brains.We stand on the brink of a tectonic shift in our understanding of ourselves that will witness the rediscovery of the central premise of Western philosophy that there is 'more than we can know'. Lucid, compelling and utterly engaging, ‘Why Us?’ offers a convincing and provocative vision of the new science of being human.

    Following in the fashion of Stephen Jay Gould and Peter Medawar, one of the world's leading scientists examines how "pure science" is in fact shaped and guided by social and political needs and assumptions.

    In The Dance of Life, developmental and stem-cell biologist Magdalena Zernicka-Goetz takes us to the front lines of efforts to understand the creation of a human life. She has spent two decades unraveling the mysteries of development, as a simple fertilized egg becomes a complex human being of forty trillion cells. Zernicka-Goetz's work is both incredibly practical and astonishingly vast: her groundbreaking experiments with mouse, human, and artificial embryo models give hope to how more women can sustain viable pregnancies. Set at the intersection of science's greatest powers and humanity's greatest concern, The Dance of Life is a revelatory account of the future of fertility -- and life itself.

    Turner's clear, insightful prose and Anton's masterly illustrations combine to offer specialists and newcomers alike an accurate and accessible guide to the evolution of cats.

    New emphasis has been given to complexity, networks, and patterns of organisation, leading to a novel kind of 'systemic' thinking. This volume integrates the ideas, models, and theories underlying the systems view of life into a single coherent framework. Taking a broad sweep through history and across scientific disciplines, the authors examine the appearance of key concepts such as autopoiesis, dissipative structures, social networks, and a systemic understanding of evolution. The implications of the systems view of life for health care, management, and our global ecological and economic crises are also discussed. Written primarily for undergraduates, it is also essential reading for graduate students and researchers interested in understanding the new systemic conception of life and its implications for a broad range of professions - from economics and politics to medicine, psychology and law.