They are the powerhouses of our cells, essential for the production and management of energy at cell level. Dr Sarah Myhill, together with Dr John McLaren Howard of Acumen Laboratories and Dr Norman Booth of Mansfield College Oxford, has spent many years studying the relationship between their malfunction and the commonest problem seen by GPs in the UK – fatigue. Their research findings have been published in three scientific papers in the International Journal of Clinical and Experimental Medicine, in 2009, 2012 and 2013. These studies showed that poor functioning of the mitochondria is the central problem in CFS. Patients with the worst mitochondrial function had the worst fatigue and vice versa. This is solid scientific evidence that CFS is a problem with mitochondria and has allowed the objective measurement of fatigue for the first time. With the publication of the third study, which showed that mitochondrial function tests and symptoms improved in patients who took measures to address their mitochondrial problems, Dr Myhill was ready to write this book. Here she explains the importance of healthy mitochondria, how we can measure their functioning and what we can do to keep them healthy, or restore them to health if problems arise. CFS is all in our cells, not in our minds!

    Her book is about the fear of an ordinary person doing extraordinary things. . . . It is good to read of someone who is just crammed full of courage, guts, spirit and determination." --Smoke Blanchard, Walking Up and Down in the WorldCindy Ross had already hiked the 2000-mile length of the Appalachian Trail when, hoping to escape a deadening daily routine and sort out her life, she returned to the wild. But this time it was a more rugged arena: the Pacific Crest Trail, a mostly mountainous, 2600-mile route from Mexico to Canada, vastly different from the relatively gentle, well-traveled Appalachian Trail.Her trip began--badly--in the California desert, where the hiking "partner" she had selected from an advertisement proved to be totally inexperienced and so strange that they parted company the first day. Continuing alone, Ross soon became the de facto leader of a motley, ever-changing crew of PCT walkers that came to be known as "Cindy's Circus." Long, rugged hiking days produced physical ailments and strong emotions, but in confronting and surmounting these challenges, Ross grew in strength. After many months and several major changes in her life, Ross beat fall snows and storms to reach the Canadian border. More than the end of the trail, this was also a symbolic milestone in her life.In narrating her story, Ross deftly brings the reader into the physical and emotional landscape of long-distance hiking. Her cast of "Crest characters" is sharply drawn in both words and sketches.

    This straightforward guide teaches you how to choose, house, feed, train, and breed the best goats for your space and needs. Whether you want to churn out fresh dairy products, harvest soft cashmere for knitting, or keep goats as playful pets, The Backyard Goat makes it easy to enjoy the benefits of owning goats, with no experience necessary.

    Although she has a vital job to do as 'Senior Pest Controller', Felix is much more than just an employee of TransPennine Express. For her colleagues and the station's commuters, Felix has changed their lives in surprising ways.Felix seems to have a remarkable ability to save the day time and again: from bringing a boy with autism out of his shell to providing comfort to a runaway child shivering on the platform one night. So when tragedy hits the team at Huddersfield, they rely on Felix to pull them together again. But it's a chance friendship with a commuter that she waits for on the platform every morning that finally gives Felix the recognition she deserves, catapulting her to international stardom...Royalties from the sale of this book will be donated to Prostate Cancer UK (registered charity 1005541, SC039332).

    In this caring book, Gary Kowalski offers warmth, guidance and wisdom for anyone facing this loss. It is a compilation of heart-warming stories, verse and photographs to provide comfort.

    People the world over have fallen in love with the stunning and deeply personal images of this rescued bird and her human family. But there is far more to Penguin's story than meets the eye. It begins with a shocking accident, in which Cameron's wife, Sam, suffers a near fatal fall that leaves her paralysed and deeply depressed.Into their lives comes Penguin, an injured magpie chick abandoned after she fell from her nest. Penguin's rescue and the incredible joy and strength she gives Sam and all those who helped her survive demonstrates that, however bleak things seem, compassion, friendship and support can come from unexpected quarters, ensuring there are always better days ahead. This plucky little magpie reminds us all that, no matter how lost, fragile or damaged we feel, accepting the love of others and loving them in return will help to make us whole.

    Tell Me Where It Hurts: A Day of Humor, Healing, and Hope in My Life as an Animal Surgeon

    Shouldn't they be lived to the fullest?Domesticated does not mean docile. The ho-hum routine of sleep, eat, eat, and sleep is no way for any creature who ruled Egypt for a millennium to spend her day. It's high time felines everywhere woke up from their cat naps and grabbed life's strings with both paws.The Devious Book for Cats offers today's discerning kitties words of wisdom and advice on everything they need to know, from in-depth guides on cardboard boxes and catnip to a brief history of the Felinism movement. It provides fail-safe tips on waking a human when you want to get fed, choosing the purr-fect gift, staring like a pro, and making the most of superstitions. It also explains the undeniable allure of the Window, the terrifying specter of the Vacuum, and how you can groom properly in just the scant twenty-four hours allotted each day.Cats: Discover the devious fun you can have when you're the one in charge!

    Kliban’s Cat, All I Need to Know I Learned from My Cat, and Bad Cat, comes a new book that answers the question all cat lovers ask: How do I make my cat like me?97 Ways to Make a Cat Like You is the perfect interactive guide to these mysterious, fickle, seemingly aloof—yet really, just particular—pets. Paired with a full-color photograph of friendly, extroverted, happy cats (in case you’ve forgotten what a cat looks like when he “likes” you), the 97 inspired, occasionally silly but always behaviorally-based tips and tricks prove that when a cat is treated right, he or she will respond in kind. Within reason. There’s the “Eye on the Ball”—record a tennis match or a Ping-Pong game on TV to play back for your cat when he needs a bit of exercise. “Cat Burrito”—wrap your cat in a towel, burrito-style, which is particularly good for anxious pets or trips to the vet. The “Boing, Boing!”—wind pipe cleaners around a pencil in a spiral shape to create springs. Carefully slide off the pencil so the spirals go “boing” when pressed. The classic “Tickle, Tickle”—tickle Kitty under her chin and softly say “gitchy, gitchy, gitchy” in your highest-pitched voice. And for the cat owner willing to go the distance, the “There’s No Business Like Show Business”—practice your best Ethel Merman by belting out favorite show tunes for your cat. Kitty won’t care if you’re off-key and she’ll enjoy the stimulation.

    Without warning an insurgent popped up, his weapon raised. At the handler's command, the dog charged their attacker. There was the flash of steel, the blur of fur, and the sound of a single shot; the handler watched his dog take a bullet. During the weeks it would take the dog to heal, the handler never left its side. The dog had saved his life. Loyal and courageous, dogs are truly man's best friend on the battlefield. While the soldiers may not always feel comfortable calling the bond they form love, the emotions involved are strong and complicated. In War Dogs, Rebecca Frankel offers a riveting mix of on-the-ground reporting, her own hands-on experiences in the military working dog world, and a look at the science of dogs' special abilities-from their amazing noses and powerful jaws to their enormous sensitivity to the emotions of their human companions. The history of dogs in the US military is long and rich, from the spirit-lifting mascots of the Civil War to the dogs still leading patrols hunting for IEDs today. Frankel not only interviewed handlers who deployed with dogs in wars from Vietnam to Iraq, but top military commanders, K-9 program managers, combat-trained therapists who brought dogs into war zones as part of a preemptive measure to stave off PTSD, and veterinary technicians stationed in Bagram. She makes a passionate case for maintaining a robust war-dog force. In a post-9/11 world rife with terrorist threats, nothing is more effective than a bomb-sniffing dog and his handler. With a compelling cast of humans and animals, this moving book is a must read for all dog lovers-military and otherwise.

    Begun as a personal challenge to create daily, the comics feature a variety of themes from the silly to the serious. Characterized by a charming drawing style and frequently featuring the cartoonist and her farcical feline Jimmy, these are the best Sunday comics you've never seen.

    Our Test Kitchens experts have paired easy side dishes and desserts with superfast entrées to create over 160 mouthwatering menus. Organized by easy-to-use food categories, including Soups, Sandwiches, Salads, Meatless Main Dishes, Fish and Shellfish, Meats, and Poultry, Cooking Light Fresh Food Fast offers recipes that are great for you and taste great, too! With short ingredient lists, straightforward procedures, fresh ingredients, and delicious results, the recipes and meals in this cookbook will be the most requested, often-repeated solutions in your weeknight repertoire.

     Each trick is rated with a difficulty rating and prerequisites to get you started quickly. Tips and troubleshooting boxes cover common problems, while Build on it! ideas suggest more complicated tricks that build on each new skill.Tricks range from simple ones like Sit, Shake Hands, Fetch, and Roll Over, to extraordinary ones like Tidy Up Your Toys into the Toybox and Get a Soda from the Fridge. Organized by theme, it's easy to find the next trick to work on with your dog. Just a few of the themes to choose from:Chores, such as Newspaper Delivery and Get Your LeashFunny tricks, such as Doggy Push-ups and Play the PianoDancing, such as Moonwalk and Chorus Line KicksLove, such as Kisses and Wave GoodbyeTrick training will help you bond with your dog and integrate him or her into your family. Tricks also help keep your dog mentally and physically healthy and establish paths of communication between you. Many tricks build skills used in dog sports, dog dancing, and dog therapy work. 101 Dog Tricks will inspire you to do more with your dog! Millions of people have found success with Kyra Sundance's step-by-step techniques—and you can, too.Also by Kyra Sundance, learn to do even more with your dog with: The Dog Tricks and Training Workbook; 51 Puppy Tricks; 10-Minute Dog Training Games; 101 Dog Tricks, Kids Edition; Dog Training 101; The Pocket Guide to Dog Tricks; Kyra’s Canine Conditioning; and The Joy of Dog Training.

    The award-winning author of Misty of Chincoteague and King of the Wind describes in vivid detail the hardworking Shire, the elegant Lipizzan, the spirited Mustang, and many more. Each description is paired with a full color illustration by Wesley Dennis. This keepsake edition is a gorgeous addition to any collection of Henry’s books and a favorite for years to come!

    Here are Buster, the kitten who arrived on Christmas; Alfred, the cat at the sweet shop; little Emily, who lived with the gentleman tramp; and Olly and Ginny, the kittens who charmed readers when they first appeared at the Herriots' house in the worldwide bestseller Every Living Thing. And along with these come others, each story as memorable and heartwarming as the last, each told with that magical blend of gentle wit and human compassion that marks every word from James Herriot's pen.