That all changed in less than a generation with the discovery and development of a new category of medicine known as antibiotics. By 1955, the age-old evolutionary relationship between humans and microbes had been transformed, trivializing once-deadly infections. William Rosen captures this revolution with all its false starts, lucky surprises, and eccentric characters. He explains why, given the complex nature of bacteria—and their ability to rapidly evolve into new forms—the only way to locate and test potential antibiotic strains is by large-scale, systematic, trial-and-error experimentation. Organizing that research needs large, well-funded organizations and businesses, and so our entire scientific-industrial complex, built around the pharmaceutical company, was born. Timely, engrossing, and eye-opening, Miracle Cure is a must-read science narrative—a drama of enormous range, combining science, technology, politics, and economics to illuminate the reasons behind one of the most dramatic changes in humanity’s relationship with nature since the invention of agriculture ten thousand years ago.

    Jonathan Eig's masterful narrative revolves around four principal characters: the fiery feminist Margaret Sanger, who was a champion of birth control in her campaign for the rights of women but neglected her own children in pursuit of free love; the beautiful Katharine McCormick, who owed her fortune to her wealthy husband, the son of the founder of International Harvester and a schizophrenic; the visionary scientist Gregory Pincus, who was dismissed by Harvard in the 1930s as a result of his experimentation with in vitro fertilization but who, after he was approached by Sanger and McCormick, grew obsessed with the idea of inventing a drug that could stop ovulation; and the telegenic John Rock, a Catholic doctor from Boston who battled his own church to become an enormously effective advocate in the effort to win public approval for the drug that would be marketed by Searle as Enovid.Spanning the years from Sanger’s heady Greenwich Village days in the early twentieth century to trial tests in Puerto Rico in the 1950s to the cusp of the sexual revolution in the 1960s, this is a grand story of radical feminist politics, scientific ingenuity, establishment opposition, and, ultimately, a sea change in social attitudes. Brilliantly researched and briskly written, The Birth of the Pill is gripping social, cultural, and scientific history.

    These are the very same behaviors that typify good soldiering and foster a sense of belonging among troops, whether they’re fighting on the front lines or engaged in non-combat activities away from the action. Drawing from history, psychology, and anthropology, bestselling author Sebastian Junger shows us just how at odds the structure of modern society is with our tribal instincts, arguing that the difficulties many veterans face upon returning home from war do not stem entirely from the trauma they’ve suffered, but also from the individualist societies they must reintegrate into.A 2011 study by the Canadian Forces and Statistics Canada reveals that 78 percent of military suicides from 1972 to the end of 2006 involved veterans. Though these numbers present an implicit call to action, the government is only just taking steps now to address the problems veterans face when they return home. But can the government ever truly eliminate the challenges faced by returning veterans? Or is the problem deeper, woven into the very fabric of our modern existence? Perhaps our circumstances are not so bleak, and simply understanding that beneath our modern guises we all belong to one tribe or another would help us face not just the problems of our nation but of our individual lives as well.Well-researched and compellingly written, this timely look at how veterans react to coming home will reconceive our approach to veteran’s affairs and help us to repair our current social dynamic.

    Together they spent a combined thirty years in prison before finally being exonerated in 2008. Meanwhile, the real killer remained free.The Cadaver King and the Country Dentist chronicles how the courts and Mississippi's death investigation system--a relic of the Jim Crow era--failed to deliver justice for its citizens and recounts the horrifying story of the two men who built successful careers on the back of this system. For nearly two decades, medical examiner Dr. Steven Hayne performed the vast majority of Mississippi's autopsies, while his friend Dr. Michael West, a local dentist, pitched himself as a forensic jack-of-all-trades. Together they became the go-to experts for prosecutors and helped put countless Mississippians in prison. But then some of those convictions began to fall apart. Radley Balko and Tucker Carrington argue that bad forensics, structural racism, and institutional failures are at fault, and raise sobering questions about our criminal justice system's ability to address them.

    Within two years he's a multimillionaire. The press calls him "King of the Bootleggers," writing breathless stories about the Gatsby-esque events he and his glamorous second wife, Imogene, host at their Cincinnati mansion, with party favors ranging from diamond jewelry for the men to brand new Pontiacs for the women. By the summer of 1921, Remus owns 35 percent of all the liquor in the United States.Pioneering prosecutor Mabel Walker Willebrandt is determined to bring him down. Willebrandt's bosses at the U.S. Attorney's office hired her right out of law school, assuming she'd pose no real threat to the cozy relationship they maintain with Remus. Eager to prove them wrong, she dispatches her best investigator, Franklin Dodge, to look into his empire. It's a decision with deadly consequences: With Remus behind bars, Dodge and Imogene begin an affair and plot to ruin him, sparking a bitter feud that soon reaches the highest levels of government--and that can only end in murder.

    Culture Warlords is the story of how Lavin, a frequent target of extremist trolls (including those at Fox News), dove into a byzantine online culture of hate and learned the intricacies of how white supremacy proliferates online.Within these pages, she reveals the extremists hiding in plain sight online: Incels. White nationalists. White supremacists. National Socialists. Proud Boys. Christian extremists. In order to showcase them in their natural habitat, Talia assumes a range of identities, going undercover as a blonde Nazi babe, a forlorn incel, and a violent Aryan femme fatale. Along the way, she discovers a whites-only dating site geared toward racists looking for love, a disturbing extremist YouTube channel run by a fourteen-year-old girl with over 800,000 followers, the everyday heroes of the antifascist movement, and much more.By combining compelling stories chock-full of catfishing and gate-crashing with her own in-depth, gut-wrenching research, she also turns the lens of anti-Semitism, racism, and white power back on itself in an attempt to dismantle and decimate the online hate movement from within. Culture Warlords explores some of the vilest subcultures on the Web-and shows us how we can fight back.

    In a clear and accessible style, Frank M. Snowden reveals the ways that diseases have not only influenced medical science and public health, but also transformed the arts, religion, intellectual history, and warfare. A multidisciplinary and comparative investigation of the medical and social history of the major epidemics, this volume touches on themes such as the evolution of medical therapy, plague literature, poverty, the environment, and mass hysteria. In addition to providing historical perspective on diseases such as smallpox, cholera, and tuberculosis, Snowden examines the fallout from recent epidemics such as HIV/AIDS, SARS, and Ebola and the question of the world’s preparedness for the next generation of diseases.

    Backed by investors such as Larry Ellison and Tim Draper, Theranos sold shares in a fundraising round that valued the company at $9 billion, putting Holmes's worth at an estimated $4.7 billion. There was just one problem: The technology didn't work.For years, Holmes had been misleading investors, FDA officials, and her own employees. When Carreyrou, working at The Wall Street Journal, got a tip from a former Theranos employee and started asking questions, both Carreyrou and the Journal were threatened with lawsuits. Undaunted, the newspaper ran the first of dozens of Theranos articles in late 2015. By early 2017, the company's value was zero and Holmes faced potential legal action from the government and her investors. Here is the riveting story of the biggest corporate fraud since Enron, a disturbing cautionary tale set amid the bold promises and gold-rush frenzy of Silicon Valley.

    To the right listener, they tell us all about themselves: where they came from, how they lived, how they died - and who killed them. Forensic scientists can unlock the mysteries of the past and help justice to be done using the messages left by a corpse, a crime scene or the faintest of human traces. Forensics uncovers the secrets of forensic medicine, drawing on interviews with top-level professionals, ground-breaking research and Val McDermid's own experience to lay bare the secrets of this fascinating science. And, along the way, she wonders at how maggots collected from a corpse can help determine time of death, how a DNA trace a millionth the size of a grain of salt can be used to convict a killer and how a team of young Argentine scientists led by a maverick American anthropologist uncovered the victims of a genocide.In her crime novels, Val McDermid has been solving complex crimes and confronting unimaginable evil for years. Now, she's looking at the people who do it for real, and real crime scenes. It's a journey that will take her to war zones, fire scenes and autopsy suites, and bring her into contact with extraordinary bravery and wickedness, as she traces the history of forensics from its earliest beginnings to the cutting-edge science of the modern day.

    She documents how the low-fat nutrition advice of the past sixty years has amounted to a vast uncontrolled experiment on the entire population, with disastrous consequences for our health.For decades, we have been told that the best possible diet involves cutting back on fat, especially saturated fat, and that if we are not getting healthier or thinner it must be because we are not trying hard enough. But what if the low-fat diet is itself the problem? What if the very foods we’ve been denying ourselves—the creamy cheeses, the sizzling steaks—are themselves the key to reversing the epidemics of obesity, diabetes, and heart disease?In this captivating, vibrant, and convincing narrative, based on a nine-year-long investigation, Teicholz shows how the misinformation about saturated fats took hold in the scientific community and the public imagination, and how recent findings have overturned these beliefs. She explains why the Mediterranean Diet is not the healthiest, and how we might be replacing trans fats with something even worse. This startling history demonstrates how nutrition science has gotten it so wrong: how overzealous researchers, through a combination of ego, bias, and premature institutional consensus, have allowed dangerous misrepresentations to become dietary dogma.With eye-opening scientific rigor, The Big Fat Surprise upends the conventional wisdom about all fats with the groundbreaking claim that more, not less, dietary fat—including saturated fat—is what leads to better health and wellness. Science shows that we have been needlessly avoiding meat, cheese, whole milk, and eggs for decades and that we can now, guilt-free, welcome these delicious foods back into our lives.

    bataar bones he was impressed. The enormous skull and teeth betrayed the apex predators close relation to the storied Tyrannosaurus rex, the most famous animal that ever lived. Prokopi's obsession with fossils had begun decades earlier, when he was a Florida boy scouring for shark teeth and Ice Age remnants, and it had continued as he built a thriving business hunting, preparing, and selling specimens to avid collectors and private museums around the world. To scientists' fury and dismay, there was big money to be made in certain corners of the fossil trade. Prokopi didn't consider himself merely a businessman, though. He also thought of himself as a vital part of paleontology--as one of the lesser-known artistic links in bringing prehistoric creatures back to life--and saw nothing wrong with turning a profit in the process. Bone hunting was expensive, risky, controversial work, and he increasingly needed bigger "scores." By the time he acquired a largely complete skeleton of T. bataar and restored it in his workshop, he was highly leveraged and drawing quiet scorn from peers who worried that by bringing such a big, beautiful Mongolian dinosaur to market he would tarnish the entire trade. Presenting the skeleton for sale at a major auction house in New York City, he was relieved to see the bidding start at nearly $1 million---only to fall apart when the president of Mongolia unexpectedly stepped in to question the specimen's origins and demand its return. An international custody battle ensued, shining new light on the black market for dinosaur fossils, the angst of scientists who fear for their field, and the precarious political tensions in post-Communist Mongolia. The Prokopi case, unprecedented in American jurisprudence, continues to reverberate throughout the intersecting worlds of paleontology, museums, art, and geopolitics.

    Torn from their homes and families, these men, women, and children were loaded into shipboard cattle stalls and abandoned in a lawless place where brutality held sway. Many did not have leprosy, and many who did were not contagious, yet all were ensnared in a shared nightmare. Here, for the first time, John Tayman reveals the complete history of the Molokai settlement and its unforgettable inhabitants. It's an epic of ruthless manhunts, thrilling escapes, bizarre medical experiments, and tragic, irreversible error. Carefully researched and masterfully told, The Colony is a searing tale of individual bravery and extraordinary survival, and stands as a testament to the power of faith, compassion, and the human spirit.

    We see it, touch it, and live in it every day. It is a habitat for a mesmerizingly complex world of micro-organisms and physical functions that are vital to our health and our survival. It is also a waste removal plant, a warning system for underlying disease and a dynamic immune barrier to infection. One of the first things people see about us, skin is crucial to our sense of identity, providing us with social significance and psychological meaning. And yet our skin and the fascinating way it functions is largely unknown to us. In prose as lucid as his research underlying it is rigorous, blending in memorable stories from the past and from his own medical experience, Monty Lyman has written a revelatory book exploring our outer surface that will surprise and enlighten in equal measure. Through the lenses of science, sociology, and history--on topics as diverse as the mechanics and magic of touch (how much goes on in the simple act of taking keys out of a pocket and unlocking a door is astounding), the close connection between the skin and the gut, what happens instantly when one gets a paper cut, and how a midnight snack can lead to sunburn--Lyman leads us on a journey across our most underrated and unexplored organ and reveals how our skin is far stranger, more wondrous, and more complex than we have ever imagined.

    But they've often been hidden in plain sight, their inventions and contributions touching our lives in ways we don't even realize.Author Claire L. Evans finally gives these unsung female heroes their due with her social history of the Broad Band, the women who made the internet what it is today. Learn from Ada Lovelace, the daughter of Lord Byron, who wove numbers into the first program for a mechanical computer in 1842. Seek inspiration from Grace Hopper, the tenacious mathematician who democratized computing by leading the charge for machine-independent programming languages after World War II. Meet Elizabeth "Jake" Feinler, the one-woman Google who kept the earliest version of the Internet online, and Stacy Horn, who ran one of the first-ever social networks on a shoestring out of her New York City apartment in the 1980s. Evans shows us how these women built and colored the technologies we can't imagine life without.Join the ranks of the pioneers who defied social convention and the longest odds to become database poets, information-wranglers, hypertext dreamers, and glass ceiling-shattering dot com-era entrepreneurs.

    Lieberman illuminates how these ongoing changes have brought many benefits, but also have created novel conditions to which our bodies are not entirely adapted, resulting in a growing incidence of obesity and new but avoidable diseases, including type-2 diabetes. He proposes that many of these chronic illnesses persist and in some cases are intensifying because of "dysevolution," a pernicious dynamic whereby only the symptoms rather than the causes of these maladies are treated. And finally—provocatively—he advocates the use of evolutionary information to help nudge, push, and sometimes oblige us to create a more salubrious environment.(With charts and line drawings throughout.)From the Hardcover edition.