There is every reason to believe that, within a few weeks of its onset, the infection was universally present in the nose and throat of the people, disseminated by mouth spray given off on talking by innumerable carriers and, in addition, by the coughing and sneezing of the sick. Susceptibility was very general, though it varied greatly in degree. Among those who escaped well marked sickness there are few who could not recall having had an occluded or running nose, or a raw feeling in the throat, or a cough, or aches and pains, at some time during the period of the prevalence of the disease, these probably representing the price such persons paid for their immunization." - Dr. Bernard Fantus In many ways, it is hard for modern people living in First World countries to conceive of a pandemic sweeping around the world and killing millions of people, and it is even harder to believe that something as common as influenza could cause such widespread illness and death. Although the flu still takes hundreds of lives each year, most of those lost are very young or old or ill with something else that had already weakened them. In fact, most people contract influenza at least once, and many suffer from the flu several times in their lives and survive it with a minimum amount of medical attention. In 1918, the world was still in the throes of the Great War, the deadliest conflict in human history at that point, but while World War I would be a catastrophic war surpassed only by World War II, an unprecedented influenza outbreak that same year inflicted casualties that would make both wars pale in comparison. An illness, or more likely a collection of illnesses, Spanish influenza quickly spread across the world and may have killed upwards of 100 million people, decimating populations across developed nations and possibly wiping out as much as 5% of the world’s population. If anything, the ongoing war and the censorship maintained by the countries fighting it may have resulted in the actual toll of the outbreak being underestimated based on the way soldiers’ deaths were categorized. World War I may have distracted people about the unprecedented nature of the outbreak, but the most alarming aspect of the outbreak in 1918 was the indiscriminate nature in which the scourge attacked young and old, healthy and unhealthy, and rich and poor alike. In fact, the popular name for the outbreak was a reference to the fact that Spain’s own king was stricken with the disease. While he and President Woodrow Wilson ended up surviving it, former First Lady Rose Cleveland did not. The staggering number of fatalities, and the way in which seemingly anybody could suffer during the outbreak, taught people in the early 20th century that regardless of the tremendous strides made by technology, and no matter how stalemated the war was, nobody was safe from nature itself. Of course, it also demonstrated how much more work could be done to prevent similar occurrences. The 1918 pandemic was neither the first nor the last outbreak of the flu, but it was by far the worst, and it forever changed the face of medicine and public health care in both North America and Europe. The 1918 Spanish Flu Pandemic: The History and Legacy of the World’s Deadliest Outbreak chronicles the devastating disease and the damage it wrought across the globe.

    Myers in his quest for unusual case studies as he unravels medical mysteries.

    Michael Baden's first-person, no-holds-barred account of his distinguished career in forensic pathology. In determining the causes of tens of thousands of deaths, from those of presidents and rock stars to victims of serial killings, exotic sex rituals, mass disasters, child abuse and drug abuse, Baden has come to the unavoidable conclusion that the search for scientific truth is often sullied by the pressures of expediency. He produces dramatic evidence to demonstrate that political intrigue, influence peddling, and professional incompetence have created a national crisis in forensic medicine.

    But most of us know very little about how the disease works, why we treat it the way we do, and the personalities whose dedication got us where we are today. For fifty years, Dr. Vincent T. DeVita Jr. has been one of those key players: he has held just about every major position in the field, and he developed the first successful chemotherapy treatment for Hodgkin’s lymphoma, a breakthrough the American Society of Clinical Oncologists has called the top research advance in half a century of chemotherapy. As one of oncology’s leading figures, DeVita knows what cancer looks like from the lab bench and the bedside. The Death of Cancer is his illuminating and deeply personal look at the science and the history of one of the world’s most formidable diseases. In DeVita’s hands, even the most complex medical concepts are comprehensible.Cowritten with DeVita’s daughter, the science writer Elizabeth DeVita-Raeburn, The Death of Cancer is also a personal tale about the false starts and major breakthroughs, the strong-willed oncologists who clashed with conservative administrators (and one another), and the courageous patients whose willingness to test cutting-edge research helped those oncologists find potential treatments. An emotionally compelling and informative read, The Death of Cancer is also a call to arms. DeVita believes that we’re well on our way to curing cancer but that there are things we need to change in order to get there. Mortality rates are declining, but America’s cancer patients are still being shortchanged—by timid doctors, by misguided national agendas, by compromised bureaucracies, and by a lack of access to information about the strengths and weaknesses of the nation’s cancer centers.With historical depth and authenticity, DeVita reveals the true story of the fight against cancer. The Death of Cancer is an ambitious, vital book about a life-and-death subject that touches us all.

    The book features case discussions, USMLE-style questions, and a USMLE-style practice exam.

    They force us to confront a fundamental biological problem: how can something as large and complex as a human body organize itself from the simplicity of a fertilized egg? A convergence of ideas from embryology, genetics, physics, networks, and control theory has begun to provide real answers. Based on the central principle of 'adaptive self-organization, ' it explains how the interactions of many cells, and of the tiny molecular machines that run them, can organize tissue structures vastly larger than themselves, correcting errors as they go along and creating new layers of complexity where there were none before.Life Unfolding tells the story of human development from egg to adult, from this perspective, showing how our whole understanding of how we come to be has been transformed in recent years. Highlighting how embryological knowledge is being used to understand why bodies age and fail, Jamie A. Daviesexplores the profound and fascinating impacts of our newfound knowledge.

    Updated to reflect the latest research in the field, and enhanced with more than 1,000 illustrations, most in full-color, the 12th Edition is the most comprehensive and modern approach to understanding medical histology available anywhere.Features: NEW full-color micrographs that comprise a complete atlas of tissue sections highlight the important features of every tissue and organ in the human body. New full-color, easy-to-understand drawings provide just the right level of detail necessary to clarify the text and make learning easier A valuable introductory chapter on laboratory methods used for the study of tissues, including the most important types of microscopy A logical organization that features chapters focusing on the cytoplasmic and nuclear compartment of the cell, the four basic tissues that form the organs, and each organ system Expanded legends that accompany each figure emphasize important points and eliminate the need to jump from image to text Medical applications explain the clinical relevance of each topic Complete coverage of every tissue of the body CD-ROM with all the images from the textVisit www.LangeTextbooks.com to access valuable resources and study aids

    Edited by Drs. Karen Marcdante, Robert M. Kliegman, Hal B. Jenson, and Richard E. Behrman, this edition's content was specifically developed in accordance with the 2009 curriculum guidelines of the Council on Medical Student Education in Pediatrics. It also includes many new and improved clinical photographs and images for enhanced visual reference. A user-friendly full-color format and online access via Student Consult facilitate study and expedite reference.

    Tragically, at the peak of her professional success, a fall on the ice and a devastating hand injury ends her surgical career. But Laura proves resilient and lands the top research job in a large pharmaceutical company. Seven years in Laura’s life separate each of the four novels in the collection. Laura’s personal life evolves just as do the threats—initiated in the dark days of Detroit—that have haunted her along the way.

    Emoto, “magnificent…genius…His research in spiritual consciousness is positively masterful.” This book will transform your world view. Dr. Masaru Emoto’s first book, The Hidden Message in Water, told about his discovery that crystals formed in frozen water revealed changes when specific, concentrated thoughts were directed toward them. He also found that water from clear springs and water that has been exposed to loving words showed brilliant, complex and colourful snowflake patters. In contrast, polluted water, or water exposed to negative though formed incomplete, asymmetrical patterns with dull colors. The implications of this research creates a new awareness of how we can positively impact the Earth and our own personal world. This book takes you further and deeper into how you can affect your own personal healing by reading it.

    In 2005, Maimonides Hospital in Brooklyn, New York, unveiled a new state-of-theart, multimillion-dollar cancer center. Determined to understand the whole spectrum of factors that determine what kind of medical care people receive in this country, bestselling author Julie Salamon spent one year tracking the progress of the center and getting to know the characters who make the hospital run. Located in a community where sixty-seven different languages are spoken, Maimonides is a case study for the particular kinds of concerns that arise in institutions that serve an increasingly multicultural American demographic. Granted an astonishing “warts and all” level of access by the hospital higher-ups, Salamon followed the doctors, patients, administrators, nurses, ambulance drivers, cooks, and cleaning staff. She explored not just the action on the ground—what happens between doctors and patients—but also the financial, ethical, technological, sociological, and cultural matters that the hospital community encounters every day. Drawing on her skills as interviewer, observer, and social critic, Salamon presents the story of modern medicine, uniquely viewed from the vantage point of those who make it run. She draws out the internal and external political machinations that exist between doctors and staff as well as between hospital and community. And she grounds the science and emotion of medical drama in the financial realities of operating a huge, private institution that must contend with issues like adapting to the specific needs of immigrant groups that make up a large and growing portion of our society. Salamon exposes struggles of both the profound and humdrum variety. There are bitter internal feuds, warm personal connections, comedy, egoism, greed, love, and loss. There are rabbinic edicts to contend with as well as imams and herbalists and local politicians. There are system foul-ups that keep blood test results from being delivered on time, careless record keepers, shortages of everything except forms to fill, recalcitrant and greedy insurance reimbursement systems, and the surprising difficulty of getting doctors to wash their hands. This is the dynamic universe of small and large concerns and personalities that, taken together, determine the nature of our care and assume the utmost importance. As Martin Payson—chairman of the board at Maimonides and ex-Time-Warner vice chairman—puts it: “Hospitals have a lot in common with the movie business. You’ve got your talent, entrepreneurs, ambition, ego stroking, the business versus the creative part. The big difference is that in the hospital you don’t get second takes. Movies are make-believe. This is real life.”

    From the woman suffering from "painful foot and moving toe syndrome" to the Indiana farmer who contacted a variant of mad cow disease from his herds of livestock, Klawans deduced a great deal from his patients, not only about the immediate causes of their ailments, but about the evolutionary underpinnings of their behavior.

    Every day the staff of emergency rooms throughout the world are saving lives - 24/7/365. Dr. Patrick Crocker provides us an intimate glimpse into the growing mind of an emergency physician, from residency to retirement. Told in a unique first-person stream of consciousness style, you are right in the middle of the action, looking over the doctor's shoulder while he works. In this compilation of notable, frightening, funny, sad, and poignant cases, you'll see Dr. Crocker's struggles to Do No Harm in the most challenging of situations. Through these stories, you'll see him find the delicate balance between help and harm, empathy and self-preservatio

    They are the powerhouses of our cells, essential for the production and management of energy at cell level. Dr Sarah Myhill, together with Dr John McLaren Howard of Acumen Laboratories and Dr Norman Booth of Mansfield College Oxford, has spent many years studying the relationship between their malfunction and the commonest problem seen by GPs in the UK – fatigue. Their research findings have been published in three scientific papers in the International Journal of Clinical and Experimental Medicine, in 2009, 2012 and 2013. These studies showed that poor functioning of the mitochondria is the central problem in CFS. Patients with the worst mitochondrial function had the worst fatigue and vice versa. This is solid scientific evidence that CFS is a problem with mitochondria and has allowed the objective measurement of fatigue for the first time. With the publication of the third study, which showed that mitochondrial function tests and symptoms improved in patients who took measures to address their mitochondrial problems, Dr Myhill was ready to write this book. Here she explains the importance of healthy mitochondria, how we can measure their functioning and what we can do to keep them healthy, or restore them to health if problems arise. CFS is all in our cells, not in our minds!

    Narrated by some of the most celebrated doctors from across the world, Dear People, with Love and Care, Your Doctors weaves together inspirational and personal stories of medical excellence and brilliance, interjected with feelings of triumph, loss, fear, strength, valour and empathy.