From a fortress-like former bank building, American Pain's doctors distributed massive quantities of oxycodone to hundreds of customers a day, mostly traffickers and addicts who came by the vanload. Inked muscle-heads ran the clinic's security. Former strippers operated the pharmacy, counting out pills and stashing cash in garbage bags. Under their lab coats, the doctors carried guns and it was all legal sort of. American Pain was the brainchild of Chris George, a 27-year-old convicted drug felon. The son of a South Florida home builder, Chris George grew up in ultra-rich Wellington, where Bill Gates, Springsteen, and Madonna kept houses. Thick-necked from weightlifting, he and his twin brother hung out with mobsters, invested in strip clubs, brawled with cops, and grinned for their mug shots. After the housing market stalled, a local doctor clued in the brothers to the burgeoning underground market for lightly regulated prescription painkillers. In Florida, pain clinics could dispense the meds, and no one tracked the patients. Seizing the opportunity, Chris George teamed up with the doctor, and word got out. Just two years later Chris had raked in $40 million, and 90 percent of the pills his doctors prescribed flowed north to feed the rest of the country's insatiable narcotics addiction. Meanwhile, hundreds more pain clinics in the mold of American Pain had popped up in the Sunshine State, creating a gigantic new drug industry. American Pain chronicles the rise and fall of this game-changing pill mill, and how it helped tip the nation into its current opioid crisis, the deadliest drug epidemic in American history. The narrative swings back and forth between Florida and Kentucky, and is populated by a gaudy and diverse cast of characters. This includes the incongruous band of wealthy bad boys, thugs and esteemed physicians who built American Pain, as well as penniless Kentucky clans who transformed themselves into painkiller trafficking rings. It includes addicts whose lives were devastated by American Pain's drugs, and the federal agents and grieving mothers who labored for years to bring the clinic's crew to justice."

    In The Most Beautiful, a title inspired by the hit song Prince wrote about their legendary love story, Mayte Garcia for the first time shares the deeply personal story of their relationship and offers a singular perspective on the music icon and their world together: from their unconventional meeting backstage at a concert (and the long-distance romance that followed), to their fairy-tale wedding (and their groundbreaking artistic partnership), to the devastating losses that ultimately dissolved their romantic relationship for good. Throughout it all, they shared a bond more intimate than any other in Prince's life. No one else can tell this story or can provide a deeper, more nuanced portrait of Prince - both the famously private man and the pioneering, beloved artist - than Mayte, his partner during some of the most pivotal personal and professional years of his career. The Most Beautiful is a book that will be returned to for decades, as Prince's music lives on with generations to come.

    A former girlfriend of Hugh Hefner describes how her years inside the Playboy Mansion went from a fairytale of A-list celebrity parties to an oppressive regime of strict rules, scheduled sex, and a total loss of identity, so much so that she even contemplated suicide.

    His congregation was racially integrated, and he was a much-lauded leader in the contemporary civil rights movement. Eventually, Jones moved his church, Peoples Temple, to northern California. He became involved in electoral politics, and soon was a prominent Bay Area leader.In this riveting narrative, Jeff Guinn examines Jones’s life, from his extramarital affairs, drug use, and fraudulent faith healing to the fraught decision to move almost a thousand of his followers to a settlement in the jungles of Guyana in South America. Guinn provides stunning new details of the events leading to the fatal day in November, 1978 when more than nine hundred people died—including almost three hundred infants and children—after being ordered to swallow a cyanide-laced drink.Guinn examined thousands of pages of FBI files on the case, including material released during the course of his research. He traveled to Jones’s Indiana hometown, where he spoke to people never previously interviewed, and uncovered fresh information from Jonestown survivors. He even visited the Jonestown site with the same pilot who flew there the day that Congressman Leo Ryan was murdered on Jones’s orders. The Road to Jonestown is the definitive book about Jim Jones and the events that led to the tragedy at Jonestown.

    In a raw, first-person account, Waite recounts each heartbreaking discovery, every life-destroying lie, and reveals what happens once the dust finally settles on her demolished marriage.After a disturbing email sparks Waite's suspicion that her husband is having an affair, she tries to uncover the truth and rebuild trust in her marriage. Instead, she finds more lies, infidelity, and betrayal than she could have imagined. Waite obsessively analyzes her relationship, trying to find a single moment from the last five years that isn't part of the long-con of lies and manipulation. With a dual-timeline narrative structure, we see Waite's romance bud, bloom, and wither simultaneously, making the heartbreak and disbelief even more affecting.

    In short, powerful chapters, Higashida explores school memories, family relationships, the exhilaration of travel, and the difficulties of speech. He also allows readers to experience profound moments we take for granted, like the thought-steps necessary for him to register that it's raining outside. Acutely aware of how strange his behavior can appear to others, he aims throughout to foster a better understanding of autism and to encourage society to see people with disabilities as people, not as problems.With an introduction by bestselling novelist David Mitchell, Fall Down 7 Times Get Up 8 also includes a dreamlike short story Higashida wrote especially for this edition. Both moving and of practical use, this book opens a window into the mind of an inspiring young man who meets every challenge with tenacity and good humor. However often he falls down, he always gets back up.

    A beach body by summer. A trip to Disneyland around the corner. A promotion on the horizon. Everyone wants to believe that they are headed toward good, better, best. But what happens when the life you hoped for is put on hold indefinitely?Kate Bowler believed that life was a series of unlimited choices, until she discovered, at age 35, that her body was wracked with cancer. In No Cure for Being Human, she searches for a way forward as she mines the wisdom (and absurdity) of today's "best life now" advice industry, which insists on exhausting positivity and on trying to convince us that we can out-eat, out-learn, and out-perform our humanness. We are, she finds, as fragile as the day we were born.With dry wit and unflinching honesty, Kate Bowler grapples with her diagnosis, her ambition, and her faith as she tries to come to terms with her limitations in a culture that says anything is possible. She finds that we need one another if we're going to tell the truth: Life is beautiful and terrible, full of hope and despair and everything in between--and there's no cure for being human.

    Confusing messages from health authorities and ineffective treatments have left many people desperate for reliable solutions. An enormous alternative industry is filling the void, selling products that are often of questionable safety and totally unknown effectiveness.In Clean, doctor and journalist James Hamblin explores how we got here, examining the science and culture of how we care for our skin today. He talks to dermatologists, microbiologists, allergists, immunologists, aestheticians, bar-soap enthusiasts, venture capitalists, Amish people, theologians, and straight-up scam artists, trying to figure out what it really means to be clean. He even experiments with giving up showers entirely, and discovers that he is not alone.Along the way he realizes that most of our standards of cleanliness are less related to health than most people think. A major part of the picture has been missing: a little-known ecosystem known as the skin microbiome--the trillions of microbes that live on our skin and in our pores. These microbes are not dangerous; they're more like an outer layer of skin that no one knew we had, and they influence everything from acne, eczema, and dry skin to how we smell. The new goal of skin care will be to cultivate a healthy biome--and to embrace the meaning of "clean" in the natural sense. This can mean doing much less, saving time, money, energy, water, and plastic bottles in the process.Lucid, accessible, and deeply researched, Clean explores the ongoing, radical change in the way we think about our skin, introducing readers to the emerging science that will be at the forefront of health and wellness conversations in coming years.

    The publication of The Rise of Theodore Roosevelt on September 14th, 2001 marks the 100th anniversary of Theodore Roosevelt becoming president.

    Eddie Huang was raised by a wild family of FOB (“fresh off the boat”) immigrants—his father a cocksure restaurateur with a dark past back in Taiwan, his mother a fierce protector and constant threat. Young Eddie tried his hand at everything mainstream America threw his way, from white Jesus to macaroni and cheese, but finally found his home as leader of a rainbow coalition of lost boys up to no good: skate punks, dealers, hip-hop junkies, and sneaker freaks. This is the story of a Chinese-American kid in a could-be-anywhere cul-de-sac blazing his way through America’s deviant subcultures, trying to find himself, ten thousand miles from his legacy and anchored only by his conflicted love for his family and his passion for food. Funny, moving, and stylistically inventive, Fresh Off the Boat is more than a radical reimagining of the immigrant memoir—it’s the exhilarating story of every American outsider who finds his destiny in the margins.

    She moved from New York to San Francisco, where she landed at a big-data startup in the heart of the Silicon Valley bubble: a world of surreal extravagance, dubious success, and fresh-faced entrepreneurs hell-bent on domination, glory, and, of course, progress.Anna arrived amidst a massive cultural shift, as the tech industry rapidly transformed into a locus of wealth and power rivaling Wall Street. But amid the company ski vacations and in-office speakeasies, boyish camaraderie and ride-or-die corporate fealty, a new Silicon Valley began to emerge: one in far over its head, one that enriched itself at the expense of the idyllic future it claimed to be building.Part coming-age-story, part portrait of an already-bygone era, Anna Wiener’s memoir is a rare first-person glimpse into high-flying, reckless startup culture at a time of unchecked ambition, unregulated surveillance, wild fortune, and accelerating political power. With wit, candor, and heart, Anna deftly charts the tech industry’s shift from self-appointed world savior to democracy-endangering liability, alongside a personal narrative of aspiration, ambivalence, and disillusionment.Unsparing and incisive, Uncanny Valley is a cautionary tale, and a revelatory interrogation of a world reckoning with consequences its unwitting designers are only beginning to understand.

    Zaman provides a chilling look at the rise of antibiotic-resistant superbugs, explaining how we got here and what we must do to address this growing global health crisis.In September 2016, a woman in Nevada became the first known case in the U.S. of a person who died of an infection resistant to every antibiotic available. Her death is the worst nightmare of infectious disease doctors and public health professionals. While bacteria live within us and are essential for our health, some strains can kill us. As bacteria continue to mutate, becoming increasingly resistant to known antibiotics, we are likely to face a public health crisis of unimaginable proportions. “It will be like the great plague of the middle ages, the influenza pandemic of 1918, the AIDS crisis of the 1990s, and the Ebola epidemic of 2014 all combined into a single threat,” Muhammad H. Zaman warns.The Biography of Resistance is Zaman’s riveting and timely look at why and how microbes are becoming superbugs. It is a story of science and evolution that looks to history, culture, attitudes and our own individual choices and collective human behavior. Following the trail of resistant bacteria from previously uncontacted tribes in the Amazon to the isolated islands in the Arctic, from the urban slums of Karachi to the wilderness of the Australian outback, Zaman examines the myriad factors contributing to this unfolding health crisis—including war, greed, natural disasters, and germophobia—to the culprits driving it: pharmaceutical companies, farmers, industrialists, doctors, governments, and ordinary people, all whose choices are pushing us closer to catastrophe.Joining the ranks of acclaimed works like Microbe Hunters, The Emperor of All Maladies, and Spillover, A Biography of Resistance is a riveting and chilling tale from a natural storyteller on the front lines, and a clarion call to address the biggest public health threat of our time.

    Yalom describes his patients' struggles -- as well as his own -- to come to terms with the two great challenges of existence: how to have a meaningful life yet reckon with its inevitable end. We meet a nurse who must stifle the pain of losing her son in order to comfort her patients' pains, a newly minted psychologist whose studies damage her treasured memories of a lost friend, and a man whose rejection of psychological inquiry forces even Yalom himself into a crisis of confidence. Creatures of a Day is a radically honest statement about the difficulties of human life, but also a celebration of some of the finest fruits -- love, family, friendship -- it can offer. Marcus Aurelius has written that "we are all creatures of a day." With Yalom as our guide, we will find the means to make our own day not only bearable, but also meaningful and joyful.

    For over 100 years the community orbited around a paper mill that employs most townspeople, including three generations of Arsenault’s own family. Years after she moved away, Arsenault realized the price she paid for her seemingly secure childhood. The mill, while providing livelihoods for nearly everyone, also contributed to the destruction of the environment and the decline of the town’s economic, physical, and emotional health in a slow-moving catastrophe, earning the area the nickname “Cancer Valley.” Mill Town is an personal investigation, where Arsenault sifts through historical archives and scientific reports, talks to family and neighbors, and examines her own childhood to illuminate the rise and collapse of the working-class, the hazards of loving and leaving home, and the ambiguous nature of toxics and disease. Mill Town is a moral wake-up call that asks, Whose lives are we willing to sacrifice for our own survival?

     Rachel Bloom has felt abnormal and out of place her whole life. In this exploration of what she thinks makes her "different," she's come to realize that a lot of people also feel this way; even people who she otherwise thought were "normal."In a collection of laugh-out-loud funny essays, all told in the unique voice (sometimes singing voice) that made her a star; Rachel writes about everything from her love of Disney, OCD and depression, weirdness, and female friendships to the story of how she didn't poop in the toilet until she was four years old; Rachel's pieces are hilarious, smart, and infinitely relatable (except for the pooping thing).