The Sackler name adorns the walls of many storied institutions: Harvard, the Metropolitan Museum of Art, Oxford, the Louvre. They are one of the richest families in the world, known for their lavish donations to the arts and sciences. The source of the family fortune was vague, however, until it emerged that the Sacklers were responsible for making and marketing OxyContin, a blockbuster painkiller that was a catalyst for the opioid crisis.Empire of Pain is a masterpiece of narrative reporting and writing, exhaustively documented and ferociously compelling.

    Today, it is the most common form of officially classified mental illness. Scott Stossel gracefully guides us across the terrain of an affliction that is pervasive yet too often misunderstood. Drawing on his own long-standing battle with anxiety, Stossel presents an astonishing history, at once intimate and authoritative, of the efforts to understand the condition from medical, cultural, philosophical, and experiential perspectives. He ranges from the earliest medical reports of Galen and Hippocrates, through later observations by Robert Burton and Søren Kierkegaard, to the investigations by great nineteenth-century scientists, such as Charles Darwin, William James, and Sigmund Freud, as they began to explore its sources and causes, to the latest research by neuroscientists and geneticists. Stossel reports on famous individuals who struggled with anxiety, as well as on the afflicted generations of his own family. His portrait of anxiety reveals not only the emotion’s myriad manifestations and the anguish anxiety produces but also the countless psychotherapies, medications, and other (often outlandish) treatments that have been developed to counteract it. Stossel vividly depicts anxiety’s human toll—its crippling impact, its devastating power to paralyze—while at the same time exploring how those who suffer from it find ways to manage and control it. My Age of Anxiety is learned and empathetic, humorous and inspirational, offering the reader great insight into the biological, cultural, and environmental factors that contribute to the affliction.

    But as a series of weather-related crop disasters put Brown and his wife, Shelly, in desperate financial straits, they started making bold changes to their farm. Brown--in an effort to simply survive--began experimenting with new practices he'd learned about from reading and talking with innovative researchers and ranchers. As he and his family struggled to keep the farm viable, they found themselves on an amazing journey into a new type of farming: regenerative agriculture.

    Eighteen years old and eager to learn, she’s invigorated by the manic energy and knife-sharp focus of the crew. By day Hannah explores the Columbia arts scene, struggling to find her place. By night she’s intoxicated by boxes of heady truffles and intrigued by the food industry’s insiders. She’s hungry for knowledge, success, and love, but she’s also ravenous because she hasn’t eaten more than yogurt and coffee in days.Hannah is hiding an eating disorder. The excruciatingly late nights, demanding chefs, bad boyfriends, and destructive obsessions have left a void inside her that she can’t fill. To reconcile her relationships with the food she worships and a body she struggles to accept, Hannah’s going to have to learn to nourish her soul.

    Now 'the greatest living advocate of the global ecosystem' this is the story of the voyages that started it all. Staying with local tribes while trekking in search of giant anteaters in Guyana, Komodo dragons in Indonesia and armadillos in Paraguay, he and the rest of the team battled with cannibal fish, aggressive tree porcupines and escape-artist wild pigs, as well as treacherous terrain and unpredictable weather, to record the incredible beauty and biodiversity of these regions. The methods may be outdated now, but the fascination and respect for the wildlife, the people and the environment - and the importance of protecting these wild places - is not.Written with his trademark wit and charm, Adventures of a Young Naturalist is not just the story of a remarkable adventure, but of the man who made us fall in love with the natural world, and who is still doing so today.

    Each dot is a ship; each ship is laden with boxes; each box is laden with goods. In postindustrial economies, we no longer produce but buy. We buy, so we must ship. Without shipping there would be no clothes, food, paper, or fuel. Without all those dots, the world would not work.Freight shipping has been no less revolutionary than the printing press or the Internet, yet it is all but invisible. Away from public scrutiny, shipping revels in suspect practices, dubious operators, and a shady system of "flags of convenience." Infesting our waters, poisoning our air, and a prime culprit of acoustic pollution, shipping is environmentally indefensible. And then there are the pirates.Rose George, acclaimed chronicler of what we would rather ignore, sails from Rotterdam to Suez to Singapore on ships the length of football fields and the height of Niagara Falls; she patrols the Indian Ocean with an anti-piracy task force; she joins seafaring chaplains, and investigates the harm that ships inflict on endangered whales.Sharply informative and entertaining, Ninety Percent of Everything reveals the workings and perils of an unseen world that holds the key to our economy, our environment, and our very civilization.

    As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned ​a curiosity ​of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020.

    A New York Times Notable Book of 2011. One of NPR's Best Books of 2011. One of Janet Maslin's Ten Picks for 2011. When the writer Donovan Hohn heard of the mysterious loss of thousands of bath toys at sea, he figured he would interview a few oceanographers, talk to a few beachcombers, and read up on Arctic science and geography. But questions can be like ocean currents: wade in too far, and they carry you away. Hohn's accidental odyssey pulls him into the secretive world of shipping conglomerates, the daring work of Arctic researchers, the lunatic risks of maverick sailors, and the shadowy world of Chinese toy factories. Moby-Duck is a journey into the heart of the sea and an adventure through science, myth, the global economy, and some of the worst weather imaginable. With each new discovery, Hohn learns of another loose thread, and with each successive chase, he comes closer to understanding where his castaway quarry comes from and where it goes. In the grand tradition of Tony Horwitz and David Quammen, Moby-Duck is a compulsively readable narrative of whimsy and curiosity.

    Serotonin is the "contentment" neurotransmitter that tells our brains we don't need any more; yet its deficiency leads to depression. Ideally, both are in optimal supply. Yet dopamine evolved to overwhelm serotonin--because our ancestors were more likely to survive if they were constantly motivated--with the result that constant desire can chemically destroy our ability to feel happiness, while sending us down the slippery slope to addiction. In the last forty years, government legislation and subsidies have promoted ever-available temptation (sugar, drugs, social media, porn) combined with constant stress (work, home, money, Internet), with the end result of an unprecedented epidemic of addiction, anxiety, depression, and chronic disease. And with the advent of neuromarketing, corporate America has successfully imprisoned us in an endless loop of desire and consumption from which there is no obvious escape.With his customary wit and incisiveness, Lustig not only reveals the science that drives these states of mind, he points his finger directly at the corporations that helped create this mess, and the government actors who facilitated it, and he offers solutions we can all use in the pursuit of happiness, even in the face of overwhelming opposition. Always fearless and provocative, Lustig marshals a call to action, with seminal implications for our health, our well-being, and our culture.

    The bedrock, the topsoil, and everything in between that generates the health of your local watershed. In his new book, Nick takes a humorous, inspiring, and elucidating trip to America's trails, farms, and frontier to celebrate the people, landscape, and stories, both historical and fresh, that have made it great.The seeds of this book were planted in 2019, when Nick took two memorable journeys with friends--a hiking trip to Glacier National Park with his friends Jeff Tweedy and George Saunders, as well as an extended visit to his friend James Rebanks, the author of A Shepherd's Life and English Pastoral. He followed that up with an excursion that could only have come about in 2020--Nick and his wife, Megan Mullally, bought an Airstream trailer to drive across the US in late 2020. All three journeys inspired some "deep-ish thinking from Nick, about the history and philosophy of our relationship with nature in our national parks, in our farming, and in our wildlife; what we mean when we talk about conservation; the importance of outdoor recreation; and the healthy building of both local and national communities across party lines, all subjects very close to Nick's heart.With witty, heartwarming stories, and a keen insight into the problems we all confront, this is both a ramble through and celebration of the land we all love.

    She was ambitious and worked hard; she had just bought an apartment; she was falling in love. But then she started to develop worrying symptoms: her face felt like it was burning whenever she was in front of the computer. Soon this progressed to an intolerance of fluorescent light, then of sunlight itself. The reaction soon spread to her entire body. Now, when her symptoms are at their worst, she must spend months on end in a blacked-out room, losing herself in audio books and elaborate word games in an attempt to ward off despair. It was during this period she began to write this book.

    Two days later, she got her first glimpse of the famous, terrifying jaws up close and she was instantly hooked; her fascination soon yielded to obsession-and an invitation to return for a full season. But as Casey readied herself for the eight-week stint, she had no way of preparing for what she would find among the dangerous, forgotten islands that have banished every campaign for civilization in the past two hundred years.

    Her goal, as co-chair of the Bill & Melinda Gates Foundation, has been to find solutions for people with the most urgent needs, wherever they live. Throughout this journey, one thing has become increasingly clear to her: If you want to lift a society up, invest in women.In this candid and inspiring book, Gates traces her awakening to the link between women's empowerment and the health of societies. She shows some of the tremendous opportunities that exist right now to “turbo-charge" change. And she provides simple and effective ways each one of us can make a difference.Convinced that all women should be free to decide whether and when to have children, Gates took her first step onto the global stage to make a stand for family planning. That step launched her into further efforts: to ensure women everywhere have access to every kind of job; to encourage men around the globe to share equally in the burdens of household work; to advocate for paid family leave for everyone; to eliminate gender bias in all its forms.Throughout, Gates introduces us to her heroes in the movement towards equality, offers startling data, shares moving conversations she's had with women from all over the world—and shows how we can all get involved.A personal statement of passionate conviction, this book tells of Gates' journey from a partner working behind the scenes to one of the world's foremost advocates for women, driven by the belief that no one should be excluded, all lives have equal value, and gender equity is the lever that lifts everything.

    Evolution, during the early nineteenth century, was an idea in the air. Other thinkers had suggested it, but no one had proposed a cogent explanation for how evolution occurs. Then, in September 1838, a young Englishman named Charles Darwin hit upon the idea that "natural selection" among competing individuals would lead to wondrous adaptations and species diversity. Twenty-one years passed between that epiphany and publication of "On the Origin of Species," The human drama and scientific basis of Darwin's twenty-one-year delay constitute a fascinating, tangled tale that elucidates the character of a cautious naturalist who initiated an intellectual revolution. "The Reluctant Mr. Darwin" is a book for everyone who has ever wondered about who this man was and what he said. Drawing from Darwin's secret "transmutation" notebooks and his personal letters, David Quammen has sketched a vivid life portrait of the man whose work never ceases to be controversial.

    With The Big Oyster, Mark Kurlansky serves up history at its most engrossing, entertaining, and delicious.