As patients, we wrongly assume the "best" care is dependent mainly on the newest medications, the most complex treatments, and the smartest doctors. But Americans look for health-care solutions in the wrong places. For example, hundreds of thousands of lives could be saved each year if doctors reduced common errors and maximized preventive medicine. For Dr. Robert Pearl, these kinds of mistakes are a matter of professional importance, but also personal significance: he lost his own father due in part to poor communication and treatment planning by doctors. And consumers make costly mistakes too: we demand modern information technology from our banks, airlines, and retailers, but we passively accept last century's technology in our health care. Solving the challenges of health care starts with understanding these problems. Mistreated explains why subconscious misperceptions are so common in medicine, and shows how modifying the structure, technology, financing, and leadership of American health care could radically improve quality outcomes. This important book proves we can overcome our fears and faulty assumptions, and provides a roadmap for a better, healthier future.

    Now it could be the key to healing millions with genetic diseases of every type—from Alzheimer's and Parkinson's to diabetes and sickle cell anemia.In 1974, Joey O'Donnell was born with strange symptoms. His insatiable appetite, incessant vomiting, and a relentless cough—which shook his tiny, fragile body and made it difficult to draw breath—confounded doctors and caused his parents agonizing, sleepless nights. After six sickly months, his salty skin provided the critical clue: he was one of thousands of Americans with cystic fibrosis, an inherited lung disorder that would most likely kill him before his first birthday.The gene and mutation responsible for CF were found in 1989—discoveries that promised to lead to a cure for kids like Joey. But treatments unexpectedly failed and CF was deemed incurable. It was only after the Cystic Fibrosis Foundation, a grassroots organization founded by parents, formed an unprecedented partnership with a fledgling biotech company that transformative leaps in drug development were harnessed to produce groundbreaking new treatments: pills that could fix the crippled protein at the root of this deadly disease.From science writer Bijal P. Trivedi, Breath from Salt chronicles the riveting saga of cystic fibrosis, from its ancient origins to its identification in the dank autopsy room of a hospital basement, and from the CF gene's celebrated status as one of the first human disease genes ever discovered to the groundbreaking targeted genetic therapies that now promise to cure it.Told from the perspectives of the patients, families, physicians, scientists, and philanthropists fighting on the front lines, Breath from Salt is a remarkable story of unlikely scientific and medical firsts, of setbacks and successes, and of people who refused to give up hope—and a fascinating peek into the future of genetics and medicine.

    Specifically targeted for the nutrition and lifestyle needs at each stage of life, this book brings and entirely new facet to the ketogenic eating trend.The book includes 80 recipes and a 16-page colour insert.

    . . This will completely change your ideas about what you should be eating."--Ruth Reichl, author of Save Me the PlumsInvestigative journalist Barry Estabrook was often on the receiving end of his doctor's scowl. Realizing he had two options--take more medication or lose weight--Estabrook chose the latter, but was paralyzed by the options. Which diet would keep the weight off? What program could he maintain over time? What diet works best--or even at all?Over the course of three years, Estabrook tried the regimens behind the most popular diets of the past forty years--from paleo, keto, gluten-free, and veganism to the Master Cleanse, Whole30, Atkins, Weight Watchers--examining the people, claims, and science behind the fads, all while recording his mental and physical experience of following each one. Along the way, he discovered that all the branded programs are derived from just three diets. There are effective, scientifically valid takeaways to be cherry-picked . . . and the rest is just marketing. Perhaps most alarming, Estabrook uncovered how short-term weight loss can do long-term health damage that may go undetected for years. Estabrook contextualizes his reporting with an analysis of our culture's bizarre dieting history, dating back to the late 1800s, to create a thorough--and thoroughly entertaining--look at what specific diets do to our bodies, why some are more effective than others, and why our relationship with food is so fraught.Estabrook's account is a relatable, pragmatic look into the ways we try to improve our health through dieting, revealing the answer may be to just eat.

    It also had an unexpected effect on its author: Orenstein realized that talking about girls is only half the conversation. Boys are subject to the same cultural forces as girls—steeped in the same distorted media images and binary stereotypes of female sexiness and toxic masculinity—which equally affect how they navigate sexual and emotional relationships. In Boys & Sex, Peggy Orenstein dives back into the lives of young people to once again give voice to the unspoken, revealing how young men understand and negotiate the new rules of physical and emotional intimacy.Drawing on comprehensive interviews with young men, psychologists, academics, and experts in the field, Boys & Sex dissects so-called locker room talk; how the word “hilarious” robs boys of empathy; pornography as the new sex education; boys’ understanding of hookup culture and consent; and their experience as both victims and perpetrators of sexual violence. By surfacing young men’s experience in all its complexity, Orenstein is able to unravel the hidden truths, hard lessons, and important realities of young male sexuality in today’s world. The result is a provocative and paradigm-shifting work that offers a much-needed vision of how boys can truly move forward as better men.

    Now, in Head Strong, Asprey shows readers how to biohack their way to a sharper, smarter, faster, more resilient brain.Imagine feeling like your mind is operating at its clearest and sharpest, and being able—possibly for the first time in your life—to do more in less time? What it suddenly became easier to do the very hardest things you do? Or if you could feel 100% confident about your intellect, and never again fear being the person in the room who just isn’t smart enough, or can’t remember something important? How would you treat people if the mood swings, short temper, and food cravings that disrupt your day could simply disappear?In Head Strong, Asprey shows us that all of this is possible—and more. Using his simple lifestyle modifications (or "hacks") to take advantage of how the structure of your brain works, readers will learn how to take their mental performance to the next level. Combining the latest findings in neuroscience and neurobiology with a hacker-inspired "get it done now" perspective, Asprey offers a program structured around key areas of brain performance that will help you:Power the brain with exactly what it needs to perform at its best all day longEliminate the sources of "kryptonite," both nutritional and environmental, that make the brain slower.Supercharge the cellular powerhouses of our brains, the mitochondria, to eliminate cravings and turn up mental focus.Reverse inflammation to perform better right now, then stay sharp and energized well into your golden years.Promote neuron growth to enhance processing speed and reinforce new learning—hotwiring your brain for success.Asprey’s easy to follow, two-week program offers a detailed plan to supercharge brain performance, including: which foods to eat and which ones to avoid, how to incorporate the right kinds of physical activity into your day, a detox protocol for your home and body; meditation and breathing for performance, recommended brain-boosting supplements; and how to adjust the lighting in your home and work space to give your brain the quality light it thrives on.A better brain—and a happier, easier, more productive life—is within reach. You just need to get Head Strong.

    In this iconoclastic book Stuart Sutherland analyses causes of irrationality and examines why we are irrational, the different kinds of irrationality, the damage it does us and the possible cures.

    Can small artists still thrive in the Internet era? Can giant record labels avoid alienating their audiences? This is a book about the pitfalls and the opportunities that creative industries (and individuals) are confronting today — about how the old models have failed or found new footing, and about what might soon replace them. An essential read for anyone with a stake in the future of the arts, Information Doesn’t Want to Be Free offers a vivid guide to the ways creativity and the Internet interact today, and to what might be coming next.

    In this incredibly personal, powerful book, Pippa Grange shows us how to face our fears and live free, fulfilled lives. A revelation.’Fearne CottonIf we were truly free from fear, what could we achieve?We strive for success, but we are rarely happy. The more we try to win – putting on a brave face for work or family – the more we risk losing ourselves. And even reaching our goals can feel strangely hollow. The culprit? Fear. It makes us anxious, or shameful, or turns us into perfectionists. We pretend to be someone else while aiming for a status that’s never truly satisfying.There is another way. A way to find our true voice, to win on our own terms. Building that open mindset is at the heart of this mould-breaking book by Dr Pippa Grange, the psychologist who helped transform the England team, taking them all the way to the World Cup semi-finals in 2018.In Fear Less, Pippa Grange shows all of us how, by starting to live with less fear, we can find our real passions and deeper fulfilment. Her simple manifesto enables us to replace stress with courage, and connect with the people around us on a far deeper level.This type of success isn’t about trophies or beating others, it’s about winning at the very deepest level: winning from within. It’s time to fear less.

    With more than one in every five people over the age of fourteen addicted, drug abuse has been called the most formidable health problem worldwide. If we are not victims ourselves, we all know someone struggling with the merciless compulsion to alter their experience by changing how their brain functions.Drawing on years of research--as well as personal experience as a recovered addict--researcher and professor Judy Grisel has reached a fundamental conclusion: for the addict, there will never be enough drugs. The brain's capacity to learn and adapt is seemingly infinite, allowing it to counteract any regular disruption, including that caused by drugs. What begins as a normal state punctuated by periods of being high transforms over time into a state of desperate craving that is only temporarily subdued by a fix, explaining why addicts are unable to live either with or without their drug. One by one, Grisel shows how different drugs act on the brain, the kind of experiential effects they generate, and the specific reasons why each is so hard to kick.Grisel's insights lead to a better understanding of the brain's critical contributions to addictive behavior, and will help inform a more rational, coherent, and compassionate response to the epidemic in our homes and communities.

    But while they may not have the best relationship or workplace advice, they certainly make you laugh, and they do know a thing or two about podcasting.In fact, the McElroy Brothers have spent the last decade making podcasts, including My Brother, My Brother and Me; The Adventure Zone; Sawbones; and more. From their start, independently producing and releasing the early episodes of My Brother, My Brother and Me, to their eleven currently available podcasts, the McElroys have become experts in creating successful podcasts. And now, they want to share what they’ve learned with you.In Everybody Has a Podcast (Except You), the McElroy Brothers will walk you through the process of turning an idea into ear-candy for legions of fans, sharing their expertise on everything from deciding on an effective name (definitely not something like My Brother, My Brother and Me), what type of microphone to use (definitely not one from the video game Rock Band), to making lots and lots of money (spoiler: you probably won’t).A must-read for anyone interested in podcasting, Everybody Has a Podcast (Except You) shares the keys to success as well as the mistakes to avoid and draws on the vast experiences of three of the funniest and most successful podcasters working today.

    In a book of unprecedented scope, McGilchrist draws on a vast body of recent brain research, illustrated with case histories, to reveal that the difference is profound—not just this or that function, but two whole, coherent, but incompatible ways of experiencing the world. The left hemisphere is detail oriented, prefers mechanisms to living things & is inclined to self-interest. The right hemisphere has greater breadth, flexibility & generosity. This division helps explain the origins of music & language, & casts new light on the history of philosophy, as well as on some mental illnesses. The 2nd part of the book takes a journey thru the history of Western culture, illustrating the tension between these two worlds as revealed in the thought & belief of thinkers & artists, from Aeschylus to Magritte. He argues that, despite its inferior grasp of reality, the left hemisphere is increasingly taking precedence in the modern world, with potentially disastrous consequences.List of IllustrationsAcknowledgmentsIntroductionAsymmetry and the brain --What do the two hemispheres 'do'? --Language, truth and music --The nature of the two worlds --The primacy of the right hemisphere --The triumph of the left hemisphere --Imitation and the evolution of culture --The ancient world --The Renaissance and the Reformation --The Enlightenment --Romanticism and the Industrial Revolution --The modern and post-modern worldsConclusionNotes BibliographyIndex

    That means most people alive today will spend more years in elderhood than in childhood, and many will be elders for 40 years or more. Yet at the very moment that humans are living longer than ever before, we've made old age into a disease, a condition to be dreaded, denigrated, neglected, and denied. Reminiscent of Oliver Sacks, noted Harvard-trained geriatrician Louise Aronson uses stories from her quarter century of caring for patients, and draws from history, science, literature, popular culture, and her own life to weave a vision of old age that's neither nightmare nor utopian fantasy--a vision full of joy, wonder, frustration, outrage, and hope about aging, medicine, and humanity itself. Elderhood is for anyone who is, in the author's own words, "an aging, i.e., still-breathing human being."

    This is our culture’s image of the perfect self. We see this person everywhere: in advertising, in the press, all over social media. We’re told that to be this person you just have to follow your dreams, that our potential is limitless, that we are the source of our own success. But this model of the perfect self can be extremely dangerous. People are suffering under the torture of this impossible fantasy. Unprecedented social pressure is leading to increases in depression and suicide. Where does this ideal come from? Why is it so powerful? Is there any way to break its spell? To answer these questions, Selfie by Will Storr takes us from the shores of Ancient Greece, through the Christian Middle Ages, to the self-esteem evangelists of 1980s California, the rise of narcissism and the selfie generation, and right up to the era of hyper-individualistic neoliberalism in which we live now. It tells the extraordinary story of the person we all know so intimately – our self.

    In fact, your body is actually endowed with many self-defense measures to hold on to fat. For example, fat can use stem cells to regenerate; increase our appetite if it feels threatened; and use bacteria, genetics, and viruses to expand itself. The secret to losing twenty pounds? You have to work with your fat, not against it. Tara explains how your fat influences your appetite and willpower, how it defends itself when attacked, and why it grows back so quickly. The Secret Life of Fat brings cutting-edge research together with historical perspectives to reveal fat’s true identity: an endocrine organ that, in the right amount, is critical to our health. Fat triggers puberty, enables our reproductive and immune systems, and even affects brain size.Although we spend $60 billion annually fighting fat, our efforts are often misinformed and misdirected. Tara expertly illustrates the complex role that genetics, hormones, diet, exercise, and history play in our weight, and The Secret Life of Fat sets you on the path to beat the bulge once and for all.