From its origins in 1738 as an almshouse and pesthouse, Bellevue today is a revered public hospital bringing first-class care to anyone in need. With its diverse, ailing, and unprotesting patient population, the hospital was a natural laboratory for the nation's first clinical research. It treated tens of thousands of Civil War soldiers, launched the first civilian ambulance corps and the first nursing school for women, pioneered medical photography and psychiatric treatment, and spurred New York City to establish the country's first official Board of Health. As medical technology advanced, "voluntary" hospitals began to seek out patients willing to pay for their care. For charity cases, it was left to Bellevue to fill the void. The latter decades of the twentieth century brought rampant crime, drug addiction, and homelessness to the nation's struggling cities problems that called a public hospital's very survival into question. It took the AIDS crisis to cement Bellevue's enduring place as New York's ultimate safety net, the iconic hospital of last resort.

    is the first deep-dive investigation of a hazardous and illicit industry that has created a worldwide epidemic, ravaging communities and overwhelming and confounding government agencies that are challenged to combat it. "A whole new crop of chemicals is radically changing the recreational drug landscape," writes Ben Westhoff. "These are known as Novel Psychoactive Substances (NPS) and they include replacements for known drugs like heroin, cocaine, ecstasy, and marijuana. They are synthetic, made in a laboratory, and are much more potent than traditional drugs"--and all-too-often tragically lethal. Drugs like fentanyl, K2, and Spice--and those with arcane acronyms like 25i-NBOMe-- were all originally conceived in legitimate laboratories for proper scientific and medicinal purposes. Their formulas were then hijacked and manufactured by rogue chemists, largely in China, who change their molecular structures to stay ahead of the law, making the drugs' effects impossible to predict. Westhoff has infiltrated this shadowy world, becoming the first journalist to report from inside an illicit Chinese fentanyls lab and providing startling and original reporting on how China's vast chemical industry operates, and how the Chinese government subsidizes it. He tracks down the little-known scientists who invented these drugs and inadvertently killed thousands, as well as a mysterious drug baron who turned the law upside down in his home country of New Zealand. Poignantly, Westhoff chronicles the lives of addicted users and dealers, families of victims, law enforcement officers, and underground drug awareness organizers in the U.S. and Europe. Together they represent the shocking and riveting full anatomy of a calamity we are just beginning to understand. From its depths, as Westhoff relates, are emerging new strategies that may provide essential long-term solutions to the drug crisis that has affected so many.

    As gripping as CSI and as eye-opening as Mary Roach’s Stiff, Carney’s The Red Market sheds a blazing new light on the disturbing, billion-dollar business of trading in human body parts, bodies, and child trafficking, raising issues and exposing corruptions almost too bizarre and shocking to imagine.

    Yet despite a century of medical progress, viral and bacterial disasters continue to take us by surprise, inciting panic and dominating news cycles. From the Spanish flu to the 1924 outbreak of pneumonic plague in Los Angeles to the 1930 “parrot fever” pandemic, through the more recent SARS, Ebola, and Zika epidemics, the last one hundred years have been marked by a succession of unanticipated pandemic alarms.In The Pandemic Century, a lively account of scares both infamous and less known, Mark Honigsbaum combines reportage with the history of science and medical sociology to artfully reconstruct epidemiological mysteries and the ecology of infectious diseases. We meet dedicated disease detectives, obstructive or incompetent public health officials, and brilliant scientists often blinded by their own knowledge of bacteria and viruses. We also see how fear of disease often exacerbates racial, religious, and ethnic tensions—even though, as the epidemiologists Malik Peiris and Yi Guan write, “‘nature’ remains the greatest bioterrorist threat of all.”Like man-eating sharks, predatory pathogens are always present in nature, waiting to strike; when one is seemingly vanquished, others appear in its place. These pandemics remind us of the limits of scientific knowledge, as well as the role that human behavior and technologies play in the emergence and spread of microbial diseases.

    In the process he tackles the question that has obsessed historians ever since: What made eighteenth-century Britain such fertile soil for inventors? Rosen’s answer focuses on a simple notion that had become enshrined in British law the century before: that people had the right to own and profit from their ideas.    The result was a period of frantic innovation revolving particularly around the promise of steam power. Rosen traces the steam engine’s history from its early days as a clumsy but sturdy machine, to its coming-of-age driving the wheels of mills and factories, to its maturity as a transporter for people and freight by rail and by sea. Along the way we enter the minds of such inventors as Thomas Newcomen and James Watt, scientists including Robert Boyle and Joseph Black, and philosophers John Locke and Adam Smith—all of whose insights, tenacity, and ideas transformed first a nation and then the world. William Rosen is a masterly storyteller with a keen eye for the “aha!” moments of invention and a gift for clear and entertaining explanations of science. The Most Powerful Idea in the World will appeal to readers fascinated with history, science, and the hows and whys of innovation itself.

    But by itself, DNA is just an inert blueprint for life. It is the ribosome--an enormous molecular machine made up of a million atoms--that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases. But this is also a human story of Ramakrishnan's unlikely journey, from his first fumbling experiments in a biology lab to being the dark horse in a fierce competition with some of the world's best scientists. In the end, Gene Machine is a frank insider's account of the pursuit of high-stakes science.

    She spent ten years training and working as an Anatomical Pathology Technologist: where the mortuary slab was her desk, and that day's corpses her task list.Past Mortems tells Carla's stories of those years, as well as investigating the body alongside our attitudes towards death - shedding light on what the living can learn from dead and the toll the work can take on the living souls who carry it out. Fascinating and insightful, Past Mortems reveals the truth about what happens when the mortuary doors swing shut or the lid of the coffin closes . . .

    In Beloved Beasts, acclaimed science journalist Michelle Nijhuis traces the movement’s history: from early battles to save charismatic species such as the American bison and bald eagle to today’s global effort to defend life on a larger scale.She describes the vital role of scientists and activists such as Aldo Leopold and Rachel Carson as well as lesser-known figures in conservation history; she reveals the origins of vital organizations like the Audubon Society and the World Wildlife Fund; she explores current efforts to protect species such as the whooping crane and the black rhinoceros; and she confronts the darker side of conservation, long shadowed by racism and colonialism.As the destruction of other species continues and the effects of climate change escalate, Beloved Beasts charts the ways conservation is becoming a movement for the protection of all species—including our own.

    A lyrical journey from hope to despair and back again, The First Cell explores cancer from every angle: medical, scientific, cultural, and personal. Indeed, Raza describes how she bore the terrible burden of being her own husband's oncologist as he succumbed to leukemia. Like When Breath Becomes Air, The First Cell is no ordinary book of medicine, but a book of wisdom and grace by an author who has devoted her life to making the unbearable easier to bear.

    In late 2017, scientists at a Hawaiian observatory glimpsed an object soaring through our inner solar system, moving so quickly that it could only have come from another star. Avi Loeb, Harvard’s top astronomer, showed it was not an asteroid; it was moving too fast along a strange orbit, and left no trail of gas or debris in its wake. There was only one conceivable explanation: the object was a piece of advanced technology created by a distant alien civilization.   In Extraterrestrial, Loeb takes readers inside the thrilling story of the first interstellar visitor to be spotted in our solar system. He outlines his controversial theory and its profound implications: for science, for religion, and for the future of our species and our planet. A mind-bending journey through the furthest reaches of science, space-time, and the human imagination, Extraterrestrial challenges readers to aim for the stars—and to think critically about what’s out there, no matter how strange it seems.

    And as outbreaks of COVID-19, Ebola, MERS, and Zika have demonstrated, we are woefully underprepared to deal with the fallout. So what can -- and must -- we do in order to protect ourselves from mankind's deadliest enemy?Drawing on the latest medical science, case studies, policy research, and hard-earned epidemiological lessons, Deadliest Enemy explores the resources and programs we need to develop if we are to keep ourselves safe from infectious disease. The authors show how we could wake up to a reality in which many antibiotics no longer cure, bioterror is a certainty, and the threat of a disastrous influenza or coronavirus pandemic looms ever larger. Only by understanding the challenges we face can we prevent the unthinkable from becoming the inevitable.Deadliest Enemy is high scientific drama, a chronicle of medical mystery and discovery, a reality check, and a practical plan of action.

    His passing on March 6, 1900, would have been unremarkable if a city health officer hadn’t noticed a swollen black lymph node on his groin—a sign of bubonic plague. Empowered by racist pseudoscience, officials rushed to quarantine Chinatown while doctors examined Wong’s tissue for telltale bacteria. If the devastating disease was not contained, San Francisco would become the American epicenter of an outbreak that had already claimed ten million lives worldwide.To local press, railroad barons, and elected officials, such a possibility was inconceivable—or inconvenient. As they mounted a cover-up to obscure the threat, ending the career of one of the most brilliant scientists in the nation in the process, it fell to federal health officer Rupert Blue to save a city that refused to be rescued. Spearheading a relentless crusade for sanitation, Blue and his men patrolled the squalid streets of fast-growing San Francisco, examined gory black buboes, and dissected diseased rats that put the fate of the entire country at risk.In the tradition of Erik Larson and Steven Johnson, Randall spins a spellbinding account of Blue’s race to understand the disease and contain its spread—the only hope of saving San Francisco, and the nation, from a gruesome fate.

    She was repeatedly hospitalized in excruciating pain, but the doctors insisted it was a urinary tract infection and sent her home with antibiotics. Unable to get out of bed, much less attend class, Norman dropped out of college and embarked on what would become a years-long journey to discover what was wrong with her. It wasn't until she took matters into her own hands--securing a job in a hospital and educating herself over lunchtime reading in the medical library--that she found an accurate diagnosis of endometriosis.In Ask Me About My Uterus, Norman describes what it was like to have her pain dismissed, to be told it was all in her head, only to be taken seriously when she was accompanied by a boyfriend who confirmed that her sexual performance was, indeed, compromised. Putting her own trials into a broader historical, sociocultural, and political context, Norman shows that women's bodies have long been the battleground of a never-ending war for power, control, medical knowledge, and truth. It's time to refute the belief that being a woman is a preexisting condition.

    To the right listener, they tell us all about themselves: where they came from, how they lived, how they died - and who killed them. Forensic scientists can unlock the mysteries of the past and help justice to be done using the messages left by a corpse, a crime scene or the faintest of human traces. Forensics uncovers the secrets of forensic medicine, drawing on interviews with top-level professionals, ground-breaking research and Val McDermid's own experience to lay bare the secrets of this fascinating science. And, along the way, she wonders at how maggots collected from a corpse can help determine time of death, how a DNA trace a millionth the size of a grain of salt can be used to convict a killer and how a team of young Argentine scientists led by a maverick American anthropologist uncovered the victims of a genocide.In her crime novels, Val McDermid has been solving complex crimes and confronting unimaginable evil for years. Now, she's looking at the people who do it for real, and real crime scenes. It's a journey that will take her to war zones, fire scenes and autopsy suites, and bring her into contact with extraordinary bravery and wickedness, as she traces the history of forensics from its earliest beginnings to the cutting-edge science of the modern day.

    Helen Macdonald's bestselling debut H is for Hawk brought the astonishing story of her relationship with goshawk Mabel to global critical acclaim and announced Macdonald as one of this century's most important and insightful nature writers. H is for Hawk won the Samuel Johnson Prize for Nonfiction and the Costa Book Award, and was a finalist for the National Book Critics Circle Award and the Kirkus Prize for Nonfiction, launching poet and falconer Macdonald as our preeminent nature essayist, with a semi-regular column in the New York Times Magazine.In Vesper Flights Helen Macdonald brings together a collection of her best loved essays, along with new pieces on topics ranging from nostalgia for a vanishing countryside to the tribulations of farming ostriches to her own private vespers while trying to fall asleep. Meditating on notions of captivity and freedom, immigration and flight, Helen invites us into her most intimate experiences: observing songbirds from the Empire State Building as they migrate through the Tribute of Light, watching tens of thousands of cranes in Hungary, seeking the last golden orioles in Suffolk's poplar forests. She writes with heart-tugging clarity about wild boar, swifts, mushroom hunting, migraines, the strangeness of birds' nests, and the unexpected guidance and comfort we find when watching wildlife. By one of this century's most important and insightful nature writers, Vesper Flights is a captivating and foundational book about observation, fascination, time, memory, love and loss and how we make sense of the world around us.