But in the inevitable condition of aging and death, the goals of medicine seem too frequently to run counter to the interest of the human spirit. Nursing homes, preoccupied with safety, pin patients into railed beds and wheelchairs. Hospitals isolate the dying, checking for vital signs long after the goals of cure have become moot. Doctors, committed to extending life, continue to carry out devastating procedures that in the end extend suffering.Gawande, a practicing surgeon, addresses his profession's ultimate limitation, arguing that quality of life is the desired goal for patients and families. Gawande offers examples of freer, more socially fulfilling models for assisting the infirm and dependent elderly, and he explores the varieties of hospice care to demonstrate that a person's last weeks or months may be rich and dignified.

    But they are under threat as never before, and their problems are spreading across the continent. The Death and Life of the Great Lakes is prize-winning reporter Dan Egan’s compulsively readable portrait of an ecological catastrophe happening right before our eyes, blending the epic story of the lakes with an examination of the perils they face and the ways we can restore and preserve them for generations to come.

    Your head hurts. You're mildly annoyed as you get the kids ready for school and dress for work yourself. Meanwhile, an epic war is being fought, just below your skin. Millions are fighting and dying for you to be able to complain as you head out the door.So what, exactly, is your immune system?Second only to the human brain in its complexity, it is one of the oldest and most critical facets of life on Earth. Without it, you would die within days. In Immune, Philipp Dettmer, the brains behind the most popular science channel on YouTube, takes readers on a journey through the fortress of the human body and its defenses. There is a constant battle of staggering scale raging within us, full of stories of invasion, strategy, defeat, and noble self-sacrifice. In fact, in the time you've been reading this, your immune system has probably identified and eradicated a cancer cell that started to grow in your body.Each chapter delves into an element of the immune system, including defenses like antibodies and inflammation as well as threats like bacteria, allergies, and cancer, as Dettmer reveals why boosting your immune system is actually nonsense, how parasites sneak their way past your body's defenses, how viruses work, and what goes on in your wounds when you cut yourself.Enlivened by engaging graphics and immersive descriptions, Immune turns one of the most intricate, interconnected, and confusing subjects—immunology—into a gripping adventure through an astonishing alien landscape. Immune is a vital and remarkably fun crash course in what is arguably, and increasingly, the most important system in the body.

    Comparing gene sequences, examining atomic structures of proteins, and looking into the geochemistry of rocks have helped explain evolution in more detail than ever before. Nick Lane expertly reconstructs the history of life by describing the ten greatest inventions of evolution (including DNA, photosynthesis, sex, and sight), based on their historical impact, role in organisms today, and relevance to current controversies. Who would have guessed that eyes started off as light-sensitive spots used to calibrate photosynthesis in algae? Or that DNA’s building blocks form spontaneously in hydrothermal vents? Lane gives a gripping, lucid account of nature’s ingenuity, and the result is a work of essential reading for anyone who has ever pondered or questioned the science underlying evolution’s greatest gifts to man.

    But it’s also messy, fallible, and about 50,000 years out of date. We cling to superstitions, remember faces but not names, miss things sitting right in front of us, and lie awake at night while our brains endlessly replay our greatest fears. Idiot Brain is for anyone who has ever wondered why their brain appears to be sabotaging their life—and what on earth it is really up to.A Library Journal Science Bestseller and a Finalist for the Goodreads Choice Award in Science Technology.

    But perhaps the wildest, and least understood, are the world's oceans: too big to police, and under no clear international authority, these immense regions of treacherous water play host to rampant criminality and exploitation.Traffickers and smugglers, pirates and mercenaries, wreck thieves and repo men, vigilante conservationists and elusive poachers, seabound abortion providers, clandestine oil-dumpers, shackled slaves and cast-adrift stowaways -- drawing on five years of perilous and intrepid reporting, often hundreds of miles from shore, Ian Urbina introduces us to the inhabitants of this hidden world. Through their stories of astonishing courage and brutality, survival and tragedy, he uncovers a globe-spanning network of crime and exploitation that emanates from the fishing, oil and shipping industries, and on which the world's economies rely.Both a gripping adventure story and a stunning expos�, this unique work of reportage brings fully into view for the first time the disturbing reality of a floating world that connects us all, a place where anyone can do anything because no one is watching.

    Over the past decade, the world has seen the most powerful El Ni�o ever recorded, the most devastating hurricane in two hundred years, the hottest European summer on record, and one of the worst storm seasons ever experienced in Florida. With one out of every five living things on this planet committed to extinction by the levels of greenhouse gases that will accumulate in the next few decades, we are reaching a global climatic tipping point. The Weather Makers is both an urgent warning and a call to arms, outlining the history of climate change, how it will unfold over the next century, and what we can do to prevent a cataclysmic future. Along with a riveting history of climate change, Tim Flannery offers specific suggestions for action for both lawmakers and individuals, from investing in renewable power sources like wind, solar, and geothermal energy, to offering an action plan with steps each and every one of us can take right now to reduce deadly CO2 emissions by as much as 70 percent.

    A group of young scientists, under the guidance of Dr. George Church, the most brilliant geneticist of our time, works to make fantasy reality by sequencing the DNA of a frozen woolly mammoth harvested from above the Arctic circle, and splicing elements of that sequence into the DNA of a modern elephant. Will they be able to turn the hybrid cells into a functional embryo and bring the extinct creatures to life in our modern world?Along with Church and his team of Harvard scientists, a world-famous conservationist and a genius Russian scientist plan to turn a tract of the Siberian tundra into Pleistocene Park, populating the permafrost with ancient herbivores as a hedge against an environmental ticking time bomb.

    Delving into topics ranging from the clash between ecological time and our culture of “perpetual now,” to the soaring history of humans changing and evolving rapidly in the face of grave threats, to rising white supremacy and fortressed borders as a form of “climate barbarism,” this is a rousing call to action for a planet on the brink. An expansive, far-ranging exploration that sees the battle for a greener world as indistinguishable from the fight for our lives, On Fire captures the burning urgency of the climate crisis, as well as the fiery energy of a rising political movement demanding a catalytic Green New Deal. “Naomi Klein’s work has always moved and guided me. She is the great chronicler of our age of climate emergency, an inspirer of generations.” —Greta Thunberg, climate activist "If I were a rich man, I’d buy 245 million copies of Naomi Klein’s 'On Fire' and hand-deliver them to every eligible voter in America…Klein is a skilled writer." —Jeff Goodell, The New York Times

    Now you can become part of the movement - and together, we can make history.It's time. This is our last chance to do anything about the global climate and ecological emergency. Our last chance to save the world as we know it.Now or never, we need to be radical. We need to rise up. And we need to rebel.Extinction Rebellion is a global activist movement of ordinary people, demanding action from Governments. This is a book of truth and action. It has facts to arm you, stories to empower you, pages to fill in and pages to rip out, alongside instructions on how to rebel - from organising a roadblock to facing arrest.By the time you finish this book you will have become an Extinction Rebellion activist. Act now before it's too late.

    This is our culture’s image of the perfect self. We see this person everywhere: in advertising, in the press, all over social media. We’re told that to be this person you just have to follow your dreams, that our potential is limitless, that we are the source of our own success. But this model of the perfect self can be extremely dangerous. People are suffering under the torture of this impossible fantasy. Unprecedented social pressure is leading to increases in depression and suicide. Where does this ideal come from? Why is it so powerful? Is there any way to break its spell? To answer these questions, Selfie by Will Storr takes us from the shores of Ancient Greece, through the Christian Middle Ages, to the self-esteem evangelists of 1980s California, the rise of narcissism and the selfie generation, and right up to the era of hyper-individualistic neoliberalism in which we live now. It tells the extraordinary story of the person we all know so intimately – our self.

    From economic development, to healthcare, to education and public policy, we rely on numbers to allocate resources and make crucial decisions. But because so much data fails to take into account gender, because it treats men as the default and women as atypical, bias and discrimination are baked into our systems. And women pay tremendous costs for this bias, in time, money, and often with their lives.Celebrated feminist advocate Caroline Criado Perez investigates the shocking root cause of gender inequality and research in Invisible Women​, diving into women’s lives at home, the workplace, the public square, the doctor’s office, and more. Built on hundreds of studies in the US, the UK, and around the world, and written with energy, wit, and sparkling intelligence, this is a groundbreaking, unforgettable exposé that will change the way you look at the world.

    Understanding someone’s pattern of behavior is the key to successful communication. Erikson breaks down the four kinds of behavior types—Reds who are dominant and commanding, Yellows who are social and optimistic, Greens who are laid back and friendly, and Blues who are analytical and precise—and explains how to identify and interact with each type of person. Instead of being bogged down with overly technical categorizations, the simple four color system allows you to speedily identify a friend or coworker and adjust how you speak and share with them.Surrounded by Idiots is full of practical information for interacting with people based on their color, including the strengths and weaknesses of all the profiles, how to give positive and negative feedback to each, and the best way to word an email when writing to someone with a different profile.

    Join author Douglas Adams and zoologist Mark Carwardine as they take off around the world in search of exotic, endangered creatures.

    The show celebrates design and architecture in all of its functional glory and accidental absurdity, with intriguing tales of both designers and the people impacted by their designs.Now, in The 99% Invisible City: A Field Guide to Hidden World of Everyday Design, host Roman Mars and coauthor Kurt Kohlstedt zoom in on the various elements that make our cities work, exploring the origins and other fascinating stories behind everything from power grids and fire escapes to drinking fountains and street signs. With deeply researched entries and beautiful line drawings throughout, The 99% Invisible City will captivate devoted fans of the show and anyone curious about design, urban environments, and the unsung marvels of the world around them.