The Sackler name adorns the walls of many storied institutions: Harvard, the Metropolitan Museum of Art, Oxford, the Louvre. They are one of the richest families in the world, known for their lavish donations to the arts and sciences. The source of the family fortune was vague, however, until it emerged that the Sacklers were responsible for making and marketing OxyContin, a blockbuster painkiller that was a catalyst for the opioid crisis.Empire of Pain is a masterpiece of narrative reporting and writing, exhaustively documented and ferociously compelling.

    A mother, wife, and working professional, Reiland was diagnosed with borderline personality disorder at the age of 29—a diagnosis that finally explained her explosive anger, manipulative behaviors, and self-destructive episodes including bouts of anorexia, substance abuse, and promiscuity. A truly riveting read with a hopeful message.

    In that short time, many doctors decide on the likely diagnosis and best treatment. Often, decisions made this way are correct, but at crucial moments they can also be wrong -- with catastrophic consequences. In this myth-shattering book, Jerome Groopman pinpoints the forces and thought processes behind the decisions doctors make. Groopman explores why doctors err and shows when and how they can -- with our help -- avoid snap judgments, embrace uncertainty, communicate effectively, and deploy other skills that can profoundly impact our health. This book is the first to describe in detail the warning signs of erroneous medical thinking and reveal how new technologies may actually hinder accurate diagnoses. How Doctors Think offers direct, intelligent questions patients can ask their doctors to help them get back on track.Groopman draws on a wealth of research, extensive interviews with some of the country’s best doctors, and his own experiences as a doctor and as a patient. He has learned many of the lessons in this book the hard way, from his own mistakes and from errors his doctors made in treating his own debilitating medical problems.How Doctors Think reveals a profound new view of twenty-first-century medical practice, giving doctors and patients the vital information they need to make better judgments together.

    Michael Mosley'This book is marvellous: buy it, share it, recommend it.... We are fortunate to have dedicated, caring and humble folks such as Doc Morgan on the Critical Care front line. We are even better off when a writer can capture all that this exciting, mad, glorious and even exasperating job means. If you work in healthcare, know somebody that does, or simply inhabit a body then this book is for you: in fact it's critical.' Peter Brindley, Professor of Critical Care Medicine, Anesthesiology, Medical Ethics University of Alberta'Just wonderful. I love the exploration of what it means to survive, at what cost and so on. Such an important factor and it's a real problem with what we do. An old surgeon once told me ‘just because we can, doesn’t mean we should. Operating is the easiest thing in the world, not doing so is incredibly challenging’. A lovely book.' Dr Nikki Stamp FRACS Cardiothoracic and Transplant Surgeon and author of Can You Die of a Broken Heart?‘An illuminating, compassionate insight into the fascinating world of intensive care.’ Leah Hazzard, author of Hard PushedCritical is an intelligent, compelling and profoundly insightful journey into the world of intensive care medicine and the lives of people who have forever been changed by it. Being critically ill means one or more of your vital organs have failed – this could be your lungs, your heart, your kidneys, gut or even your brain. Starting with the first recognised case in which a little girl was saved by intensive care in 1952 in Copenhagen, Matt writes brilliantly about the fascinating history, practices and technology in this newest of all the major medical specialties. Matt guides us around the ICU by guiding us around the body and the different organs, and in this way, we learn not only the stories of many of the patients he’s treated over the years, but also about the various functions different parts of the body.   He draws on his time spent with real patients, on the brink of death, and explains how he and his colleagues fight against the odds to help them live. Happily many of his cases have happy endings, but Matt also writes movingly about those cases which will always remain with him – the cases where the mysteries of the body proved too hard to solve, or diagnoses came too late or made no difference to the outcome.

    During that year of physical recovery, Runyon began to question what he’d done, undertaking the complicated journey from near-death back to high school, and from suicide back to the emotional mainstream of life.In the tradition of Running with Scissors and Girl, Interrupted, The Burn Journals is a truly remarkable book about teenage despair and recovery.

    A group of young scientists, under the guidance of Dr. George Church, the most brilliant geneticist of our time, works to make fantasy reality by sequencing the DNA of a frozen woolly mammoth harvested from above the Arctic circle, and splicing elements of that sequence into the DNA of a modern elephant. Will they be able to turn the hybrid cells into a functional embryo and bring the extinct creatures to life in our modern world?Along with Church and his team of Harvard scientists, a world-famous conservationist and a genius Russian scientist plan to turn a tract of the Siberian tundra into Pleistocene Park, populating the permafrost with ancient herbivores as a hedge against an environmental ticking time bomb.

    He spends his days fending off anxious mums, elderly sex maniacs and hopeless hypochondriacs. The rest of his time is taken up by sparring with colleagues, battling bureaucrats and banging his head against the brick walls of the NHS.

    Using mostly short entries organized from A to Z, many of which are cross-referenced, Rosenthal captures in wonderful and episodic detail the moments, observations, and emotions that comprise a contemporary life. Start anywhere—preferably at the beginning—and see how one young woman’s alphabetized existence can open up and define the world in new and unexpected ways.An ordinary life, perhaps, but an extraordinary book.Cross-section of ordinary life at this exact momentA security guard is loosening his belt.A couple is at a sushi restaurant with some old friends. They are reminiscing. In the back of their minds, they are thinking of being home.A woman is trying to suck on a cherry Lifesaver but will end up biting it in six seconds.A little boy is riding the train home with his dad after spending the day together at his office.A man is running back into a grocery store to look for a scarf he dropped. He will leave with the phone number of a woman who will become his wife.Words the author meant to useFlair, Luxurious, Panoply, Churlish, Dainty, FollyWines that go nicely with this bookreds: Marcel Lapierre Morgon (France), Alario Dolcetto d’Alba Costa Fiore (Italy) whites: King Estate Pinot Gris (Oregon), Landmark Chardonnay Overlook (CaliforniaBook, standing in the bookstore holding aIf I am standing there with the book in my hand, one of three things has already happened: Friend recommended it. Read a good review. Cover caught my eye. I can appreciate a cool cover. But it’s like the extra credit part of a test—it only enhances an already solid grade. Getting it right won’t help if most everything else is wrong. And getting it wrong won’t hurt if most everything else is right. (There are countless books I cherish whose covers I don’t like too much, or cannot even now recall.) The interior of the book—the terrain of its pages, where all those words took me, the tiny but very real spot it ultimately occupies in my mind—that becomes the book. Next I go to the flaps. The front flap needs to intrigue/not bore me, and the bio needs to tell me just enough about the author. I’ll do my best to extract the author’s entire existence from their 2-X-2 inch photo.Off to the back cover. I’ll be momentarily impressed when I see a blurb by a hot writer like ____, but I know that it is just as likely that I’ll like the book as hate it regardless of these quotes. I look at them in a more voyeuristic way, like a literary gaper’s delay: Wow, the author knows So and So. Bet they send each other clever text messages. Really the only thing I can gauge from the blurbs is my own pathetic jealousy level.To get a true sense of the book, I have to spend a minute inside. I’ll glance at the first couple pages, then flip to the middle, see if the language matches me somehow. It’s like dating, only with sentences. Some sentences, no matter how well-dressed or nice, just don’t do it for me. Others I click with instantly. It could be something as simple yet weirdly potent as a single word choice (tangerine). We’re meant to be, that sentence and me. And when it happens, you just know.

    The Olympic gold medalist offers an account of her life with her skating partner and husband, Sergei Grinkov, from their first introduction and successive skating championships, to their marriage, to the fatal heart attack that took Sergei's life.

    As this question fills the airwaves with anticipation, their legions of fans continue to multiply and ask a different series of questions, like—Who are these people?What’s the secret to their success? And is Chip actually that funny in real life? By renovating homes in Waco, Texas, and changing lives in such a winsome and engaging way, Chip and Joanna have become more than just the stars of Fixer Upper, they have become America’s new best friends.The Magnolia Story is the first book from Chip and Joanna, offering their fans a detailed look at their life together. From the very first renovation project they ever tackled together, to the project that nearly cost them everything; from the childhood memories that shaped them, to the twists and turns that led them to the life they share on the farm today.They both attended Baylor University in Waco. However, their paths did not cross until Chip checked his car into the local Firestone tire shop where Joanna worked behind the counter. Even back then Chip was a serial entrepreneur who, among other things, ran a lawn care company, sold fireworks, and flipped houses. Soon they were married and living in their first fixer upper. Four children and countless renovations later, Joanna garners the attention of a television producer who notices her work on a blog one day.In The Magnolia Story fans will finally get to join the Gaines behind the scenes and discover:-The time Chip ran to the grocery store and forgot to take their new, sleeping baby-Joanna’s agonizing decision to close her dream business to focus on raising their children-When Chip buys a houseboat, sight-unseen, and it turns out to be a leaky wreck-Joanna’s breakthrough moment of discovering the secret to creating a beautiful home-Harrowing stories of the financial ups and downs as an entrepreneurial couple-Memories and photos from Chip and Jo’s wedding-The significance of the word magnolia and why it permeates everything they do-The way the couple pays the popularity of Fixer Upper forward, sharing the success with others, and bolstering the city of Waco along the wayAnd yet there is still one lingering question for fans of the show: Is Chip really that funny? “Oh yeah,” says Joanna. “He was, and still is, my first fixer upper.”

    During her 24-hour shifts at Heathrow, Dr Green had to be ready for anything: from finding an abandoned suitcase leaking blood onto the carousel, to discovering a man smuggling heroin in a corset.It's a job that brought her into contact with all walks of life; her patients included drug mules and fugitives, schizophrenics and stowaways, refugees and tourists. And with the threats of a nerve agent poisoning or a Level Four viral epidemic always in the back of her mind, Dr Green found herself on the frontline where the decisions are made about who - or what - was allowed to leave the airport's borders.FLIGHT RISK reveals the drama that takes place behind-the-scenes of an airport and what is needed to make critical decisions in this hidden no-man's land of geopolitics, terror, tragedy and medicine.

    Styron is perhaps the first writer to convey the full terror of depression's psychic landscape, as well as the illuminating path to recovery.

    She tried everything to appease her wakefulness: from medication to therapy, changes in her diet to changes in her living arrangements. Nothing seemed to help.The Shapeless Unease is Harvey's darkly funny and deeply intelligent anatomy of her insomnia, an immersive interior monologue of a year without one of the most basic human needs. Original and profound, and narrated with a lucid breathlessness, this is a startlingly insightful exploration of memory, writing and influence, death and the will to survive, from "this generation's Virginia Woolf" (Telegraph).

    In this sensational and macabre story, we meet the surgeon who counted not only luminaries Benjamin Franklin, Lord Byron, Adam Smith, and Thomas Gainsborough among his patients but also “resurrection men” among his close acquaintances. A captivating portrait of his ruthless devotion to uncovering the secrets of the human body, and the extraordinary lengths to which he went to do so—including body snatching, performing pioneering medical experiments, and infecting himself with venereal disease—this rich historical narrative at last acknowledges this fascinating man and the debt we owe him today.

    Q, an internationally renowned neurosurgeon and neuroscientist who leads cutting-edge research to cure brain cancer. But not too long ago, he was Freddy, a nineteen-year-old undocumented migrant worker toiling in the tomato fields of central California. In this gripping memoir, Alfredo Quiñones-Hinojosa tells his amazing life story—from his impoverished childhood in the tiny village of Palaco, Mexico, to his harrowing border crossing and his transformation from illegal immigrant to American citizen and gifted student at the University of California at Berkeley and at Harvard Medical School. Packed with adventure and adversity—including a few terrifying brushes with death—Becoming Dr. Q is a testament to persistence, hard work, the power of hope and imagination, and the pursuit of excellence. It’s also a story about the importance of family, of mentors, and of giving people a chance.