How many of us understand the way seizures affect the brain, how the heart is connected to wellbeing, or the why the foot carries the key to our humanity? In Adventures in Human Being, award-winning author Gavin Francis leads readers on a journey into the hidden pathways of the human body, offering a guide to its inner workings and a celebration of its marvels.Drawing on his experiences as a surgeon, ER specialist, and family physician, Francis blends stories from the clinic with episodes from medical history, philosophy, and literature to describe the body in sickness and in health, in living and in dying. At its heart, Adventures in Human Being is a meditation on what it means to be human. Poetic, eloquent, and profoundly perceptive, this book will transform the way you view your body.

    And yet, in our popular conception it exists largely as a footnote to World War I.In Pale Rider, Laura Spinney recounts the story of an overlooked pandemic, tracing it from Alaska to Brazil, from Persia to Spain, and from South Africa to Odessa. She shows how the pandemic was shaped by the interaction of a virus and the humans it encountered; and how this devastating natural experiment put both the ingenuity and the vulnerability of humans to the test.Laura Spinney writes that the Spanish flu was as significant – if not more so – as two world wars in shaping the modern world; in disrupting, and often permanently altering, global politics, race relations, family structures, and thinking across medicine, religion and the arts.

    We take for granted that we can remember, feel emotion, navigate, empathize, and understand the world around us, but how would our lives change if these abilities were dramatically enhanced--or disappeared overnight?Helen Thomson has spent years traveling the world, tracking down incredibly rare brain disorders. In Unthinkable she tells the stories of nine extraordinary people she encountered along the way. From the man who thinks he's a tiger to the doctor who feels the pain of others just by looking at them to a woman who hears music that’s not there, their experiences illustrate how the brain can shape our lives in unexpected and, in some cases, brilliant and alarming ways.Story by remarkable story, Unthinkable takes us on an unforgettable journey through the human brain. Discover how to forge memories that never disappear, how to grow an alien limb, and how to make better decisions. Learn how to hallucinate and how to make yourself happier in a split second. Find out how to avoid getting lost, how to see more of your reality, even how exactly you can confirm you are alive. Think the unthinkable.

    By examining the unseen and unconscious environmental impacts in four areas-the Internet and technology, food, fashion, and fuel - Schlossberg helps readers better understand why climate change is such a complicated issue, and how it connects all of us: How streaming a movie on Netflix in New York burns coal in Virginia; how eating a hamburger in California might contribute to pollution in the Gulf of Mexico; how buying an inexpensive cashmere sweater in Chicago expands the Mongolian desert; how destroying forests from North Carolina is necessary to generate electricity in England. Cataloging the complexities and frustrations of our carbon-intensive society with a dry sense of humor, Schlossberg makes the climate crisis and its solutions interesting and relevant to everyone who cares, even a little, about the planet. She empowers readers to think about their stuff and the environment in a new way, helping them make more informed choices when it comes to the future of our world. Most importantly, this is a book about the power we have as voters and consumers to make sure that the fight against climate change includes all of us and all of our stuff, not just industry groups and politicians. If we have any hope of solving the problem, we all have to do it together. "A compelling-and illuminating-look at how our daily habits impact the environment."--Vanity Fair"Shows how even the smallest decisions can have profound environmental consequences."--The New York Times

    The book is suitable for use as a text in similar overview courses about genes and social issues or genes and disease. It gives a good overview of the developments and status of this field for a wide range of biomedical researchers, physicians, and students, especially those interested in the prospects for the new, genetics-based personalized medicine.

    She has a perspective like that of no other expert in the field, which allows her to offer unparalleled observations and groundbreaking ideas.People with autism can often think the way animals think, putting them in the perfect position to translate "animal talk." Grandin is a faithful guide into their world, exploring animal pain, fear, aggression, love, friendship, communication, learning, and, yes, even animal genius. The sweep of Animals in Translation is immense and will forever change the way we think about animals.*includes a Behavior and Training Troubleshooting Guide Among its provocative ideas, the book:~argues that language is not a requirement for consciousness--and that animals do have consciousness.~applies the autism theory of "hyper-specificity" to animals, showing that animals and autistic people are so sensitive to detail that they "can't see the forest for the trees"--a talent as well as a "deficit".~explores the "interpreter" in the normal human brain that filters out detail, leaving people blind to much of the reality that surrounds them--a reality animals and autistic people see, sometimes all too clearly.~explains how animals have "superhuman" skills: animals have animal genius.~compares animals to autistic savants, declaring that animals may in fact be autistic savants, with special forms of genius that normal people do not possess and sometimes cannot even see.~examines how humans and animals use their emotions to think, to decide, and even to predict the future.~reveals the remarkable abilities of handicapped people and animals .~maintains that the single worst thing you can do to an animal is to make it feel afraid.

    We ignore this reality most of the time, but when a new threat (Ebola, SARS, Zika) seems imminent, we send our best and bravest doctors to contain it--people like Dr. Ali S. Khan.In his long career as a public health first responder—protected by a thin mask from infected patients, napping under nets to keep out scorpions, making life-and-death decisions on limited, suspect information—Khan has found that rogue microbes will always be a problem, but outbreaks are often caused by people. We make mistakes, politicize emergencies, and, too often, fail to imagine the consequences of our actions.The Next Pandemic is a firsthand account of disasters like anthrax, bird flu, and others and how we could do more to prevent their return. It's both a gripping story of our brushes with fate and an urgent lesson on how we can keep ourselves safe from the inevitable next pandemic.

    With more than one in every five people over the age of fourteen addicted, drug abuse has been called the most formidable health problem worldwide. If we are not victims ourselves, we all know someone struggling with the merciless compulsion to alter their experience by changing how their brain functions.Drawing on years of research--as well as personal experience as a recovered addict--researcher and professor Judy Grisel has reached a fundamental conclusion: for the addict, there will never be enough drugs. The brain's capacity to learn and adapt is seemingly infinite, allowing it to counteract any regular disruption, including that caused by drugs. What begins as a normal state punctuated by periods of being high transforms over time into a state of desperate craving that is only temporarily subdued by a fix, explaining why addicts are unable to live either with or without their drug. One by one, Grisel shows how different drugs act on the brain, the kind of experiential effects they generate, and the specific reasons why each is so hard to kick.Grisel's insights lead to a better understanding of the brain's critical contributions to addictive behavior, and will help inform a more rational, coherent, and compassionate response to the epidemic in our homes and communities.

    The bestselling author of Shadow Divers returns with a riveting story of exploration, mystery, and the discovery of an unknown world--this time about one man's incredible odyssey from blindness into sight.

    In Papua New Guinea, a primitive tribe is nearly obliterated by a sickness whose chief symptom is uncontrollable laughter. Across Europe, millions of sheep rub their fleeces raw before collapsing. In England, cows attack their owners in the milking parlors, while in the American West, thousands of deer starve to death in fields full of grass.What these strange conditions–including fatal familial insomnia, kuru, scrapie, and mad cow disease–share is their cause: prions. Prions are ordinary proteins that sometimes go wrong, resulting in neurological illnesses that are always fatal. Even more mysterious and frightening, prions are almost impossible to destroy because they are not alive and have no DNA–and the diseases they bring are now spreading around the world.In The Family That Couldn’t Sleep, essayist and journalist D. T. Max tells the spellbinding story of the prion’s hidden past and deadly future

    In the midst of all this death, a bizarre disease appeared in Europe. Eventually known as encephalitis lethargica, or sleeping sickness, it would spread across the world, leaving millions dead or locked in institutions. Then, in 1927, it would disappear as suddenly as it had arrived-or so the doctors at first thought. Asleep, set in 1920s and '30s New York, follows a group of neurologists through hospitals and insane asylums as they try to solve this worldwide epidemic. The symptoms could include not only unending sleep but dangerous insomnia, facial tics, catatonia, Parkinson's, and even violent insanity. Molly Caldwell Crosby, acclaimed author of The American Plague, explores the frightening history of this forgotten disease- and details the frantic effort to conquer it before it strikes again.

    bataar bones he was impressed. The enormous skull and teeth betrayed the apex predators close relation to the storied Tyrannosaurus rex, the most famous animal that ever lived. Prokopi's obsession with fossils had begun decades earlier, when he was a Florida boy scouring for shark teeth and Ice Age remnants, and it had continued as he built a thriving business hunting, preparing, and selling specimens to avid collectors and private museums around the world. To scientists' fury and dismay, there was big money to be made in certain corners of the fossil trade. Prokopi didn't consider himself merely a businessman, though. He also thought of himself as a vital part of paleontology--as one of the lesser-known artistic links in bringing prehistoric creatures back to life--and saw nothing wrong with turning a profit in the process. Bone hunting was expensive, risky, controversial work, and he increasingly needed bigger "scores." By the time he acquired a largely complete skeleton of T. bataar and restored it in his workshop, he was highly leveraged and drawing quiet scorn from peers who worried that by bringing such a big, beautiful Mongolian dinosaur to market he would tarnish the entire trade. Presenting the skeleton for sale at a major auction house in New York City, he was relieved to see the bidding start at nearly $1 million---only to fall apart when the president of Mongolia unexpectedly stepped in to question the specimen's origins and demand its return. An international custody battle ensued, shining new light on the black market for dinosaur fossils, the angst of scientists who fear for their field, and the precarious political tensions in post-Communist Mongolia. The Prokopi case, unprecedented in American jurisprudence, continues to reverberate throughout the intersecting worlds of paleontology, museums, art, and geopolitics.

    Lisa Sanders, author of the monthly New York Times Magazine column "Diagnosis," the inspiration for the hit Fox TV series House, M.D.The experience of being ill can be like waking up in a foreign country. Life, as you formerly knew it, is on hold while you travel through this other world as unknown as it is unexpected. When I see patients in the hospital or in my office who are suddenly, surprisingly ill, what they really want to know is, ‘What is wrong with me?’ They want a road map that will help them manage their new surroundings. The ability to give this unnerving and unfamiliar place a name, to know it–on some level–restores a measure of control, independent of whether or not that diagnosis comes attached to a cure. Because, even today, a diagnosis is frequently all a good doctor has to offer.A healthy young man suddenly loses his memory–making him unable to remember the events of each passing hour. Two patients diagnosed with Lyme disease improve after antibiotic treatment–only to have their symptoms mysteriously return. A young woman lies dying in the ICU–bleeding, jaundiced, incoherent–and none of her doctors know what is killing her. In Every Patient Tells a Story, Dr. Lisa Sanders takes us bedside to witness the process of solving these and other diagnostic dilemmas, providing a firsthand account of the expertise and intuition that lead a doctor to make the right diagnosis.Never in human history have doctors had the knowledge, the tools, and the skills that they have today to diagnose illness and disease. And yet mistakes are made, diagnoses missed, symptoms or tests misunderstood. In this high-tech world of modern medicine, Sanders shows us that knowledge, while essential, is not sufficient to unravel the complexities of illness. She presents an unflinching look inside the detective story that marks nearly every illness–the diagnosis–revealing the combination of uncertainty and intrigue that doctors face when confronting patients who are sick or dying. Through dramatic stories of patients with baffling symptoms, Sanders portrays the absolute necessity and surprising difficulties of getting the patient’s story, the challenges of the physical exam, the pitfalls of doctor-to-doctor communication, the vagaries of tests, and the near calamity of diagnostic errors. In Every Patient Tells a Story, Dr. Sanders chronicles the real-life drama of doctors solving these difficult medical mysteries that not only illustrate the art and science of diagnosis, but often save the patients’ lives.

    Shubin describes how over the last half-century, scientists have been able to explore how genetic recipes build bodies during embryological development--how these inventions and adaptations occur in a nonprogressive manner in different contexts, at different speeds. Paleontology has been transformed over the last 50 years by tools and techniques of molecular biology--and it is that revolution in our understanding of the evolution of life that Shubin traces here. Each of us is a mosaic of precursors that came about at different times and places, with deep rooted connections across species that Darwin, for all he understood, could never even have imagined.

    Vaccines and antibiotics, the mainstays of modern medicine, have not been able to conquer infectious microbes because of their amazing ability to adapt, evolve, and spread to new places. Terrorism aside, one of the greatest dangers from infectious disease we face today is from a massive outbreak of drug-resistant microbes.Deadly Outbreaks recounts the scientific adventures of a special group of intrepid individuals who investigate these outbreaks around the world and figure out how to stop them. Part homicide detective, part physician, these medical investigators must view the problem from every angle, exhausting every possible source of contamination. Any data gathered in the field must be stripped of human sorrows and carefully analyzed into hard statistics.Author Dr. Alexandra Levitt is an expert on emerging diseases and other public health threats. Here she shares insider accounts she’s collected that go behind the alarming headlines we’ve seen in the media: mysterious food poisonings, unexplained deaths at a children’s hospital, a strange neurologic disease afflicting slaughterhouse workers, flocks of birds dropping dead out of the sky, and drug-resistant malaria running rampant in a refugee camp. Meet the resourceful investigators—doctors, veterinarians, and research scientists—and discover the truth behind these cases and more.