Not just any cheese. This was Paramo de Guzman, a rare Spanish queso reputed to be the finest, and most expensive, in the world. The cheese carried its own legend: Made from an ancient family recipe in the medieval Castilian village of Guzman (pop. 80), the cheese was submerged in olive oil and aged in a cave where it gained magical qualities-if you ate it, some said, you might recover long-lost memories. Too broke to actually buy the cheese, Paterniti made a quixotic vow: that he would meet this cheese again someday. Flash forward ten years, when Paterniti has finally found his way-family in tow-to that tiny hilltop village to meet the famous cheesemaker himself, a voluble, magnetic, heartbroken genius named Ambrosio. What Paterniti discovers in Guzman is nothing like the idyllic slow-food fable he has imagined. Instead, he wanders into-and eventually becomes deeply implicated in-the heart of an unfolding mystery, in which a village begins to spill its long-held secrets, and nothing is quite what it seems.

    In the aftermath of that critical moment, his once-carefree life would be consumed by confrontations with medical incompetence, discrimination that almost cost him his education and employment, physical abuse, and dark moments when he contemplated suicide.This is the story of one man's battle to pursue his dreams despite an often incapacitating brain disorder. From his early experiences of fear and denial to his exasperating search for treatment, Eichenwald provides a deeply candid account of his years facing this misunderstood and often stigmatized condition. He details his encounters with the doctors whose negligence could have killed him, but for the heroic actions of a brilliant neurologist and the family and friends who fought for him.Many of Eichenwald's recollections are drawn from his diaries, vivid and painstakingly kept records that helped sharpen his skills as a journalist. He raises important questions about the nature of memory, the revelations of brain science, and the profound mysteries of human perception.Ultimately, A Mind Unraveled is an inspirational story, one that chronicles how Eichenwald, faced often with his own mortality, transformed trauma into a guide for reaching the future he desired. Defying relentless threats to his emotional and physical well-being, he affirmed his decision to never give up, and in the process learned how to rise from the depths of despair to the heights of unimagined success.

    Karen, Cathy, Angela, Sally, Diana. Sheila. Meet the Ames Girls: eleven childhood friends who formed a special bond growing up in Ames, Iowa. As young women, they moved to eight different states, yet managed to maintain an enduring friendship that would carry them through college and careers, marriage and motherhood, dating and divorce, a child’s illness and the mysterious death of one member of their group. Capturing their remarkable story, The Girls from Ames is a testament to the deep bonds of women as they experience life’s joys and challenges — and the power of friendship to triumph over heartbreak and unexpected tragedy.The girls, now in their forties, have a lifetime of memories in common, some evocative of their generation and some that will resonate with any woman who has ever had a friend. Photograph by photograph, recollection by recollection, occasionally with tears and often with great laughter, their sweeping and moving story is shared by Jeffrey Zaslow, Wall Street Journal columnist, as he attempts to define the matchless bonds of female friendship. It demonstrates how close female relationships can shape every aspect of women’s lives – their sense of themselves, their choice of men, their need for validation, their relationships with their mothers, their dreams for their daughters – and reveals how such friendships thrive, rewarding those who have committed to them.The Girls from Ames is the story of a group of ordinary women who built an extraordinary friendship. With both universal insights and deeply personal moments, it is a book that every woman will relate to and be inspired by.

    Today he is the director of the Center for Compassion and Altruism Research and Education (CCARE) at Stanford University, of which the Dalai Lama is a founding benefactor. But back then his life was at a dead end until at twelve he wandered into a magic shop looking for a plastic thumb. Instead he met Ruth, a woman who taught him a series of exercises to ease his own suffering and manifest his greatest desires. Her final mandate was that he keep his heart open and teach these techniques to others. She gave him his first glimpse of the unique relationship between the brain and the heart.Doty would go on to put Ruth’s practices to work with extraordinary results—power and wealth that he could only imagine as a twelve-year-old, riding his orange Sting-Ray bike. But he neglects Ruth’s most important lesson, to keep his heart open, with disastrous results—until he has the opportunity to make a spectacular charitable contribution that will virtually ruin him. Part memoir, part science, part inspiration, and part practical instruction, Into the Magic Shop shows us how we can fundamentally change our lives by first changing our brains and our hearts.

    En route, John Cleese describes his nerve-racking first public appearance, at St Peter’s Preparatory School at the age of eight and five-sixths; his endlessly peripatetic home life with parents who seemed incapable of staying in any house for longer than six months; his first experiences in the world of work as a teacher who knew nothing about the subjects he was expected to teach; his hamster-owning days at Cambridge; and his first encounter with the man who would be his writing partner for over two decades, Graham Chapman. And so on to his dizzying ascent via scriptwriting for Peter Sellers, David Frost, Marty Feldman and others to the heights of Monty Python.Punctuated from time to time with John Cleese’s thoughts on topics as diverse as the nature of comedy, the relative merits of cricket and waterskiing, and the importance of knowing the dates of all the kings and queens of England, this is a masterly performance by a former schoolmaster.

    Every story he wrote had one thing in common―they didn't have an ending. The killer was still out there.But after the sudden death of a friend, crime writer and author of I'll Be Gone in the Dark, Michelle McNamara, Billy became fed up. Following a dark night, he came up with a plan. A plan to investigate past the point when the cops had given up. A plan to solve the murders himself.You'll ride shotgun as Billy identifies the Halloween Mask Murderer, finds a missing girl in the California Redwoods, and investigates the only other murder in New York City on 9/11. You'll hear intimate details of the hunts for two of the most terrifying serial killers in history: his friend Michelle McNamara's pursuit of the Golden State Killer and his own quest to find the murderer of the Allenstown Four. And Billy gives you the tools―and the rules―to help solve murders yourself.Gripping, complex, unforgettable, Chase Darkness with Me is an examination of the evil forces that walk among us, illustrating a novel way to catch those killers, and a true-crime narrative unlike any you've read before.

    These “psychosurgeons,” as they called themselves, occupied a gray zone between medical research and medical practice, and ended up subjecting untold numbers of people to the types of surgical experiments once limited to chimpanzees.The most important test subject to emerge from this largely untold chapter in American history was a twenty-seven-year-old factory worker named Henry Molaison. In 1953, Henry—who suffered from severe epilepsy—received a radical new version of the lobotomy, one that targeted the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry left the operating room profoundly amnesic, unable to create new long-term memories. Over the next sixty years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.Luke Dittrich uses the case of Patient H.M. as a starting point for a kaleidoscopic journey, one that moves from the first recorded brain surgeries in ancient Egypt to the cutting-edge laboratories of MIT. He takes readers inside the old asylums and operating theaters where psychosurgeons conducted their human experiments, and behind the scenes of a bitter custody battle over the ownership of the most important brain in the world. Throughout, Dittrich delves into the enduring mysteries of the mind while exposing troubling stories of just how far we’ve gone in our pursuit of knowledge. It is also, at times, a deeply personal journey. Dittrich’s grandfather was the brilliant, morally complex surgeon who operated on Molaison—and thousands of other patients. The author’s investigation into the dark roots of modern memory science ultimately forces him to confront unsettling secrets in his own family history, and to reveal the tragedy that fueled his grandfather’s relentless experimentation—experimentation that would revolutionize our understanding of ourselves.Patient H.M. combines the best of biography, memoir, and science journalism to create a haunting, endlessly fascinating story, one that reveals the wondrous and devastating things that can happen when hubris, ambition, and human imperfection collide.

    He wanted to learn Arabic, explore Cairo's neighborhoods, and visit the legendary archaeological digs of Upper Egypt. After his years of covering China for The New Yorker, friends warned him Egypt would be a much quieter place. But not long before he arrived, the Egyptian Arab Spring had begun, and now the country was in chaos.In the midst of the revolution, Hessler often traveled to digs at Amarna and Abydos, where locals live beside the tombs of kings and courtiers, a landscape that they call simply al-Madfuna "the Buried." He and his wife set out to master Arabic, striking up a friendship with their instructor, a cynical political sophisticate. They also befriended Peter's translator, a gay man struggling to find happiness in Egypt's homophobic culture. A different kind of friendship was formed with the neighborhood garbage collector, an illiterate but highly perceptive man named Sayyid, whose access to the trash of Cairo would be its own kind of archaeological excavation. Hessler also met a family of Chinese small-business owners in the lingerie trade; their view of the country proved a bracing counterpoint to the West's conventional wisdom.Through the lives of these and other ordinary people in a time of tragedy and heartache, and through connections between contemporary Egypt and its ancient past, Hessler creates an astonishing portrait of a country and its people. What emerges is a book of uncompromising intelligence and humanity--the story of a land in which a weak state has collapsed but its underlying society remains in many ways painfully the same. A worthy successor to works like Rebecca West's Black Lamb and Grey Falcon and Bruce Chatwin's The Songlines, The Buried bids fair to be recognized as one of the great books of our time.

    Leslie Jamison deftly excavates the stories we tell about addiction--both her own and others'--and examines what we want these stories to do, and what happens when they fail us.All the while, she offers a fascinating look at the larger history of the recovery movement, and at the literary and artistic geniuses whose lives and works were shaped by alcoholism and substance dependence, including John Berryman, Jean Rhys, Raymond Carver, Billie Holiday, David Foster Wallace, and Denis Johnson, as well as brilliant figures lost to obscurity but newly illuminated here.For the power of her striking language and the sharpness of her piercing observations, Jamison has been compared to such iconic writers as Joan Didion and Susan Sontag. Yet her utterly singular voice also offers something new. With enormous empathy and wisdom, Jamison has given us nothing less than the story of addiction and recovery in America writ large, a definitive and revelatory account that will resonate for years to come.

    Brian Goldman is both an emergency room physician at Mount Sinai and a prominent medical journalist. Never one to shy away from controversy, Goldman specializes in kicking open the doors to the medical establishment, revealing what really goes on behind the scenes -- and in the minds of doctors and nurses.In The Night Shift, Goldman shares his experiences in the witching hours at Mount Sinai Hospital in downtown Toronto. We meet the kinds of patients who walk into an ER after midnight: late-night revellers injured on their way home after last call, teens assaulted in the streets by other teens and a woman who punches another woman out of jealousy over a man. But Goldman also reveals the emotional, heartbreaking side of everyday ER visits: adult children forced to make life and death decisions about critically ill parents, victims of sexual assault, and mentally ill and homeless patients looking for understanding and a quick fix in the twenty-four hour waiting room. Written with Goldman's trademark honesty and with surprising humour, The Night Shift is also a frank look at many issues facing the medical profession today, and offers a highly compelling inside view into an often shrouded world.

    Theodore Dalrymple, a British psychiatrist who treats the poor in a slum hospital and a prison in England, has seemingly seen it all. Yet in listening to and observing his patients, he is continually astonished by the latest twist of depravity that exceeds even his own considerable experience. Dalrymple's key insight in Life at the Bottom is that long-term poverty is caused not by economics but by a dysfunctional set of values, one that is continually reinforced by an elite culture searching for victims. This culture persuades those at the bottom that they have no responsibility for their actions and are not the molders of their own lives. Drawn from the pages of the cutting-edge political and cultural quarterly City Journal, Dalrymple's book draws upon scores of eye-opening, true-life vignettes that are by turns hilariously funny, chillingly horrifying, and all too revealing-sometimes all at once. And Dalrymple writes in prose that transcends journalism and achieves the quality of literature.

    Its architectural treasures crumble—foundations shift, marble ornaments fall—even as efforts to preserve them are underway. The City of Falling Angels opens on the evening of January 29, 1996, when a dramatic fire destroys the historic Fenice opera house. The loss of the Fenice, where five of Verdi's operas premiered, is a catastrophe for Venetians. Arriving in Venice three days after the fire, Berendt becomes a kind of detective—inquiring into the nature of life in this remarkable museum-city—while gradually revealing the truth about the fire.In the course of his investigations, Berendt introduces us to a rich cast of characters: a prominent Venetian poet whose shocking "suicide" prompts his skeptical friends to pursue a murder suspect on their own; the first family of American expatriates that loses possession of the family palace after four generations of ownership; an organization of high-society, partygoing Americans who raise money to preserve the art and architecture of Venice, while quarreling in public among themselves, questioning one another's motives and drawing startled Venetians into the fray; a contemporary Venetian surrealist painter and outrageous provocateur; the master glassblower of Venice; and numerous others-stool pigeons, scapegoats, hustlers, sleepwalkers, believers in Martians, the Plant Man, the Rat Man, and Henry James.Berendt tells a tale full of atmosphere and surprise as the stories build, one after the other, ultimately coming together to reveal a world as finely drawn as a still-life painting. The fire and its aftermath serve as a leitmotif that runs throughout, adding the elements of chaos, corruption, and crime and contributing to the ever-mounting suspense of this brilliant book.

    These invisible casualties of the Great Recession have taken to the road by the tens of thousands in RVs and modified vans, forming a growing community of nomads.Nomadland tells a revelatory tale of the dark underbelly of the American economy—one which foreshadows the precarious future that may await many more of us. At the same time, it celebrates the exceptional resilience and creativity of these Americans who have given up ordinary rootedness to survive, but have not given up hope.

    His goal: to learn how such an overhyped industry could possibly sustain itself as long as it has. Determined to cut through the clichés of big tech—the relentless optimism, the incessant repetition of vacuous buzzwords—Pein decided that he would need to take an approach as unorthodox as the companies he would soon be covering. To truly understand the delirious reality of a Silicon Valley entrepreneur, he knew, he would have to inhabit that perspective—he would have to become an entrepreneur. Thus he begins his journey—skulking through gimmicky tech conferences, pitching his over-the-top business ideas to investors, and interviewing a cast of outrageous characters: cyborgs and con artists, Teamsters and transhumanists, jittery hackers and naive upstart programmers whose entire lives are managed by their employers—who work endlessly and obediently, never thinking to question their place in the system.In showing us this frantic world, Pein challenges the positive self-image that the tech tycoons have crafted—as benevolent creators of wealth and opportunity—to reveal their self-justifying views and their insidious visions for the future. Vivid and incisive, Live Work Work Work Die is a troubling portrait of a self-obsessed industry bent on imposing its disturbing visions on the rest of us.

    Despite her flapping arms and shaking legs, she continued to speak clearly and was able to finish her speech. It was as if she had suddenly become two people: a calm orator and a shuddering wreck. Then the seizures happened again and again. The Shaking Woman tracks Hustvedt’s search for a diagnosis, one that takes her inside the thought processes of several scientific disciplines, each one of which offers a distinct perspective on her paroxysms but no ready solution. In the process, she finds herself entangled in fundamental questions: What is the relationship between brain and mind? How do we remember? What is the self?During her investigations, Hustvedt joins a discussion group in which neurologists, psychiatrists, psychoanalysts, and brain scientists trade ideas to develop a new field: neuropsychoanalysis. She volunteers as a writing teacher for psychiatric in-patients at the Payne Whitney clinic in New York City and unearths precedents in medical history that illuminate the origins of and shifts in our theories about the mind-body problem. In The Shaking Woman, Hustvedt synthesizes her experience and research into a compelling mystery: Who is the shaking woman? In the end, the story she tells becomes, in the words of George Makari, author of Revolution in Mind, “a brilliant illumination for us all.”