Joshua Mezrich creates life from loss, transplanting organs from one body to another. In this intimate, profoundly moving work, he illuminates the extraordinary field of transplantation that enables this kind of miracle to happen every day.When Death Becomes Life is a thrilling look at how science advances on a grand scale to improve human lives. Mezrich examines more than one hundred years of remarkable medical breakthroughs, connecting this fascinating history with the inspiring and heartbreaking stories of his transplant patients. Combining gentle sensitivity with scientific clarity, Mezrich reflects on his calling as a doctor and introduces the modern pioneers who made transplantation a reality—maverick surgeons whose feats of imagination, bold vision, and daring risk taking generated techniques and practices that save millions of lives around the world.Mezrich takes us inside the operating room and unlocks the wondrous process of transplant surgery, a delicate, intense ballet requiring precise timing, breathtaking skill, and at times, creative improvisation. In illuminating this work, Mezrich touches the essence of existence and what it means to be alive. Most physicians fight death, but in transplantation, doctors take from death. Mezrich shares his gratitude and awe for the privilege of being part of this transformative exchange as the dead give their last breath of life to the living. After all, the donors are his patients, too.When Death Becomes Life also engages in fascinating ethical and philosophical debates: How much risk should a healthy person be allowed to take to save someone she loves? Should a patient suffering from alcoholism receive a healthy liver? What defines death, and what role did organ transplantation play in that definition? The human story behind the most exceptional medicine of our time, Mezrich’s riveting book is a beautiful, poignant reminder that a life lost can also offer the hope of a new beginning.

    She has managed to achieve this in spite of being diagnosed as schizophrenic and given a "grave" prognosis—and suffering the effects of her illness throughout her life.Saks was only eight, and living an otherwise idyllic childhood in sunny 1960s Miami, when her first symptoms appeared in the form of obsessions and night terrors. But it was not until she reached Oxford University as a Marshall Scholar that her first full-blown episode, complete with voices in her head and terrifying suicidal fantasies, forced her into a psychiatric hospital.Saks would later attend Yale Law School where one night, during her first term, she had a breakdown that left her singing on the roof of the law school library at midnight. She was taken to the emergency room, force-fed antipsychotic medication, and tied hand-and-foot to the cold metal of a hospital bed. She spent the next five months in a psychiatric ward.So began Saks's long war with her own internal demons and the equally powerful forces of stigma. Today she is a chaired professor of law who researches and writes about the rights of the mentally ill. She is married to a wonderful man.In The Center Cannot Hold, Elyn Saks discusses frankly and movingly the paranoia, the inability to tell imaginary fears from real ones, and the voices in her head insisting she do terrible things, as well as the many obstacles she overcame to become the woman she is today. It is destined to become a classic in the genre.

    But the world she wanted did not exist yet, so she set out to create it. In this spirited account, King details her life's journey to find her true self. She recounts her groundbreaking tennis successes that came at a breathtaking pace--six years as the top-ranked woman in the world, twenty Wimbledon championships, thirty-nine grand-slam titles, and her watershed defeat of Bobby Riggs in the famous Battle of the Sexes. King poignantly recalls the cultural backdrop of her career and the profound impact on her worldview from the women's movement, the assassinations and anti-war protests of the 1960s, the civil rights movement, and, eventually, the LGBTQ+ rights movement.King describes the myriad challenges she hurdled, including entrenched sexism, an eating disorder, near financial ruin after being outed, and accepting her sexual identity. It was not until the age of 51 that she began to publicly and unequivocally acknowledge, I am gay. Today, King's life remains one of indefatigable service. She offers insights and advice on leadership, business, activism, sports, politics, marriage equality, parenting, sexuality and love. She shows how living honestly and openly has had a transformative effect on her relationships and happiness. Hers is the story of a pathbreaking feminist, world-class athlete, and an indomitable spirit whose impact has transcended her achievements in sports.

    Doctor, Harvard professor, renowned infectious-disease specialist, anthropologist, the recipient of a MacArthur "genius" grant, world-class Robin Hood, Farmer was brought up in a bus and on a boat, and in medical school found his life’s calling: to diagnose and cure infectious diseases and to bring the lifesaving tools of modern medicine to those who need them most.Mountains Beyond Mountains takes us from Harvard to Haiti, Peru, Cuba, and Russia as Farmer changes minds and practices through his dedication to the philosophy that "the only real nation is humanity"—a philosophy that is embodied in the small public charity he founded, Partners in Health. He enlists the help of the Gates Foundation, George Soros, the U.N.’s World Health Organization, and others in his quest to cure the world. At the heart of this book is the example of a life based on hope, and on an understanding of the truth of the Haitian proverb "Beyond mountains there are mountains": as you solve one problem, another problem presents itself, and so you go on and try to solve that one too.

    For most of that time, she didn't know why. All of her trips to the ER and her daily anguish, pain, and lethargy only ever resulted in one question: How could any one person be this sick? Several drug addictions, three major hospitalizations, and over $100,000 later, she finally had a diagnosis: late-stage Lyme disease. Sick is Khakpour's arduous, emotional journey—as a woman, a writer, and a lifelong sufferer of undiagnosed health problems—through the chronic illness that perpetually left her a victim of anxiety, living a life stymied by an unknown condition.Divided by settings, Khakpour guides the reader through her illness by way of the locations that changed her course—New York, LA, New Mexico, and Germany—as she meditates on both the physical and psychological impacts of uncertainty, and the eventual challenge of accepting the diagnosis she had searched for over the course of her adult life. With candor and grace, she examines her subsequent struggles with mental illness, her addiction to the benzodiazepines prescribed by her psychiatrists, and her ever-deteriorating physical health. A story about survival, pain, and transformation, Sick is a candid, illuminating narrative of hope and uncertainty, boldly examining the deep impact of illness on one woman's life.

    She made headlines again when she was stripped of her citizenship and resigned from the Dutch Parliament.Infidel shows the coming of age of this distinguished political superstar and champion of free speech as well as the development of her beliefs, iron will, and extraordinary determination to fight injustice. Raised in a strict Muslim family, Hirsi Ali survived civil war, female mutilation, brutal beatings, adolescence as a devout believer during the rise of the Muslim Brotherhood, and life in four troubled, unstable countries ruled largely by despots. She escaped from a forced marriage and sought asylum in the Netherlands, where she earned a college degree in political science, tried to help her tragically depressed sister adjust to the West, and fought for the rights of Muslim women and the reform of Islam as a member of Parliament. Under constant threat, demonized by reactionary Islamists and politicians, disowned by her father, and expelled from family and clan, she refuses to be silenced.Ultimately a celebration of triumph over adversity, Hirsi Ali’s story tells how a bright little girl evolves out of dutiful obedience to become an outspoken, pioneering freedom fighter. As Western governments struggle to balance democratic ideals with religious pressures, no other book could be more timely or more significant.

    Born in Yemen, and raised in Ireland, Wales and post-war England, he lost his mother at the age of six. In his teens, he dropped out of university and took to the streets of London as part of a two-man escape act; when his partner went on vacation, Izzard kept busy by inventing a one-man act, and thus a career was ignited. As a stand-up comedian, Izzard has captivated audiences with his surreal, stream-of-consciousness comedy--lines such as "Cake or Death?" "Death Star Canteen," and "Do You Have a Flag?" have the status of great rock lyrics. As a self-proclaimed "Executive Transvestite," Izzard broke the mold performing in full make-up and heels, and has become as famous for his advocacy for LGBT rights as he has for his art. In Believe Me, he recounts the dizzying rise he made from street busking to London's West End, to Wembley Stadium and New York's Madison Square Garden. Still performing more than 100 shows a year--thus far in a record-breaking twenty-eight countries worldwide--Izzard is arguably one of today's top Kings of Comedy. With his brand of keenly intelligent humor, that ranges from world history to pop culture, politics and philosophy, he has built an extraordinary fan base that transcends age, gender, and race. Writing with the same candor and razor-sharp insight evident in his comedy, he reflects on a childhood marked by unutterable loss, sexuality and coming out, as well as a life in show business, politics, and philanthropy. Honest and generous, Izzard's Believe Me is an inspired account of a very singular life thus far.

    The childhood illness that left her bedridden for a year, which she was not expected to survive. A teenage yearning to escape that nearly ended in disaster. An encounter with a disturbed man on a remote path. And, most terrifying of all, an ongoing, daily struggle to protect her daughter--for whom this book was written--from a condition that leaves her unimaginably vulnerable to life's myriad dangers.Seventeen discrete encounters with Maggie at different ages, in different locations, reveal a whole life in a series of tense, visceral snapshots. In taut prose that vibrates with electricity and restrained emotion, O'Farrell captures the perils running just beneath the surface, and illuminates the preciousness, beauty, and mysteries of life itself.

    Many people think of microbes as germs to be eradicated, but those that live with us—the microbiome—build our bodies, protect our health, shape our identities, and grant us incredible abilities. In this astonishing book, Ed Yong takes us on a grand tour through our microbial partners, and introduces us to the scientists on the front lines of discovery. Yong, whose humor is as evident as his erudition, prompts us to look at ourselves and our animal companions in a new light—less as individuals and more as the interconnected, interdependent multitudes we assuredly are. The microbes in our bodies are part of our immune systems and protect us from disease. Those in cows and termites digest the plants they eat. In the deep oceans, mysterious creatures without mouths or guts depend on microbes for all their energy. Bacteria provide squids with invisibility cloaks, help beetles to bring down forests, and allow worms to cause diseases that afflict millions of people. I Contain Multitudes is the story of these extraordinary partnerships, between the creatures we are familiar with and those we are not. It reveals how we humans are disrupting these partnerships and how we might manipulate them for our own good. It will change both our view of nature and our sense of where we belong in it.

    He’s an established legend, having starred in Mary Poppins, Chitty Chitty Bang Bang, and The Dick Van Dyke Show. And yet he’s still keeping himself busy, entertaining America on television, movies, the stage, and social media. Everyone wonders, “How does he do it?” For the first time, Van Dyke shares his secrets and tips on old age: Just keep moving. In a fun and folksy way of addressing readers, Keep Moving serves as an instruction book on how to embrace old age with a positive attitude. The chapters are filled with exclusive personal anecdotes that explore various themes on aging: how to adapt to the physical and social changes, deal with loss of friends and loved ones, stay current, fall in love again, and “keep moving” every day like there’s no tomorrow.

    Hatshepsut, the daughter of a general who took Egypt's throne without status as a king’s son and a mother with ties to the previous dynasty, was born into a privileged position of the royal household. Married to her brother, she was expected to bear the sons who would legitimize the reign of her father’s family. Her failure to produce a male heir was ultimately the twist of fate that paved the way for her inconceivable rule as a cross-dressing king. At just twenty, Hatshepsut ascended to the rank of king in an elaborate coronation ceremony that set the tone for her spectacular twenty-two year reign as co-regent with Thutmose III, the infant king whose mother Hatshepsut out-maneuvered for a seat on the throne. Hatshepsut was a master strategist, cloaking her political power plays with the veil of piety and sexual expression. Just as women today face obstacles from a society that equates authority with masculinity, Hatshepsut had to shrewdly operate the levers of a patriarchal system to emerge as Egypt's second female pharaoh.Hatshepsut had successfully negotiated a path from the royal nursery to the very pinnacle of authority, and her reign saw one of Ancient Egypt’s most prolific building periods. Scholars have long speculated as to why her images were destroyed within a few decades of her death, all but erasing evidence of her rule. Constructing a rich narrative history using the artifacts that remain, noted Egyptologist Kara Cooney offers a remarkable interpretation of how Hatshepsut rapidly but methodically consolidated power—and why she fell from public favor just as quickly. The Woman Who Would Be King traces the unconventional life of an almost-forgotten pharaoh and explores our complicated reactions to women in power.

    Based on eight years of research, extensive archival materials, new documents, and exclusive access to Perkins’s family members and friends, this biography is the first complete portrait of a devoted public servant with a passionate personal life, a mother who changed the landscape of American business and society.Frances Perkins was named Secretary of Labor by Franklin Roosevelt in 1933. As the first female cabinet secretary, she spearheaded the fight to improve the lives of America’s working people while juggling her own complex family responsibilities. Perkins’s ideas became the cornerstones of the most important social welfare and legislation in the nation’s history, including unemployment compensation, child labor laws, and the forty-hour work week. Arriving in Washington at the height of the Great Depression, Perkins pushed for massive public works projects that created millions of jobs for unemployed workers. She breathed life back into the nation’s labor movement, boosting living standards across the country. As head of the Immigration Service, she fought to bring European refugees to safety in the United States. Her greatest triumph was creating Social Security. Written with a wit that echoes Frances Perkins’s own, award-winning journalist Kirstin Downey gives us a riveting exploration of how and why Perkins slipped into historical oblivion, and restores Perkins to her proper place in history.

    (I understand that it’s likely the former, which is a fancy “book” way of saying “the first one.”) I talk about my grandparents, doing stand-up comedy as a teenager, bar mitzvahs, and Jewish summer camp, and tell way more stories about doing drugs than my mother would like. I also talk about some of my adventures in Los Angeles, and surely say things about other famous people that will create a wildly awkward conversation for me at a party one day. I hope you enjoy the book should you buy it, and if you don’t enjoy it, I’m sorry. If you ever see me on the street and explain the situation, I’ll do my best to make it up to you.

    The daughter of immigrants, she was raised in an Oakland, California community that cared deeply about social justice; her parents--an esteemed economist from Jamaica and an admired cancer researcher from India--met as activists in the civil rights movement when they were graduate students at Berkeley. Growing up, Harris herself never hid her passion for justice, and when she became a prosecutor out of law school, a deputy district attorney, she quickly established herself as one of the most innovative change agents in American law enforcement. She progressed rapidly to become the elected District Attorney for San Francisco, and then the chief law enforcement officer of the state of California as a whole. Known for bringing a voice to the voiceless, she took on the big banks during the foreclosure crisis, winning a historic settlement for California's working families. Her hallmarks were applying a holistic, data-driven approach to many of California's thorniest issues, always eschewing stale "tough on crime" rhetoric as presenting a series of false choices. Neither "tough" nor "soft" but smart on crime became her mantra. Being smart means learning the truths that can make us better as a community, and supporting those truths with all our might. That has been the pole star that guided Harris to a transformational career as the top law enforcement official in California, and it is guiding her now as a transformational United States Senator, grappling with an array of complex issues that affect her state, our country, and the world, from health care and the new economy to immigration, national security, the opioid crisis, and accelerating inequality.By reckoning with the big challenges we face together, drawing on the hard-won wisdom and insight from her own career and the work of those who have most inspired her, Kamala Harris offers in The Truths We Hold a master class in problem-solving, in crisis management, and leadership in challenging times. Through the arc of her own life, on into the great work of our day, she communicates a vision of shared struggle, shared purpose, and shared values. In a book rich in many home truths, not least is that a relatively small number of people work very hard to convince a great many of us that we have less in common than we actually do, but it falls to us to look past them and get on with the good work of living our common truth. When we do, our shared effort will continue to sustain us and this great nation, now and in the years to come.

    In suburban America, Azadeh lived in two worlds. At home, she was the daughter of the Iranian exile community, serving tea, clinging to tradition, and dreaming of Tehran. Outside, she was a California girl who practiced yoga and listened to Madonna. For years, she ignored the tense standoff between her two cultures. But college magnified the clash between Iran and America, and after graduating, she moved to Iran as a journalist. This is the story of her search for identity, between two cultures cleaved apart by a violent history. It is also the story of Iran, a restive land lost in the twilight of its revolution. Moaveni's homecoming falls in the heady days of the country's reform movement, when young people demonstrated in the streets and shouted for the Islamic regime to end. In these tumultuous times, she struggles to build a life in a dark country, wholly unlike the luminous, saffron and turquoise-tinted Iran of her imagination. As she leads us through the drug-soaked, underground parties of Tehran, into the hedonistic lives of young people desperate for change, Moaveni paints a rare portrait of Iran's rebellious next generation. The landscape of her Tehran -- ski slopes, fashion shows, malls and cafes -- is populated by a cast of young people whose exuberance and despair brings the modern reality of Iran to vivid life.