But Maurice Hilleman came close. Maurice Hilleman is the father of modern vaccines. Chief among his accomplishments are nine vaccines that practically every child gets, rendering formerly deadly diseases — including mumps, rubella, and measles — nearly forgotten. Author Paul A. Offit's rich and lively narrative details Hilleman's research and experiences as the basis for a larger exploration of the development of vaccines, covering two hundred years of medical history and traveling across the globe in the process. The history of vaccines necessarily brings with it a cautionary message, as they have come under assault from those insisting they do more harm than good. Paul Offit clearly and compellingly rebuts these arguments, and, by demonstrating how much the work of Hilleman and others has gained for humanity, shows us how much we have to lose.

    As a result, antibiotic resistance now ranks among the gravest medical problems of modern times. Good Germs, Bad Germs addresses not only this issue but also what has become known as the "hygiene hypothesis"-- an argument that links the over-sanitation of modern life to now-epidemic increases in immune and other disorders. In telling the story of what went terribly wrong in our war on germs, Jessica Snyder Sachs explores our emerging understanding of the symbiotic relationship between the human body and its resident microbes--which outnumber its human cells by a factor of nine to one! The book also offers a hopeful look into a future in which antibiotics will be designed and used more wisely, and beyond that, to a day when we may replace antibacterial drugs and cleansers with bacterial ones--each custom-designed for maximum health benefits.

    Lab 257 blows the lid off the stunning true nature and checkered history of Plum Island. It shows that the seemingly bucolic island in the shadow of New York City is a ticking biological time bomb that none of us can safely ignore.Based on declassified government documents, in-depth interviews, and access to Plum Island itself, this is an eye-opening, suspenseful account of a federal government germ laboratory gone terribly wrong. For the first time, Lab 257 takes you deep inside this secret world and presents startling revelations on virus outbreaks, biological meltdowns, infected workers, the periodic flushing of contaminated raw sewage into area waters, and the insidious connections between Plum Island, Lyme disease, and the deadly West Nile virus. The book also probes what's in store for Plum Island's new owner, the Department of Homeland Security, in this age of bioterrorism.Lab 257 is a call to action for those concerned with protecting present and future generations from preventable biological catastrophes.

    From biblical plagues, to the AIDS crisis, to supergerms of the future, this updated and revised edition of the original covers the whole gamut of diseases that have threatened humanity since its origins.It also includes a new chapter on the history of bioterrorism and the deplorable role it has played and is likely to play in the phenomenal diversity of diseases.

    It’s so bound up with our deepest feelings that emotional trauma causes it to change shape.Practising cardiologist Sandeep Jauhar beautifully weaves his own experiences with the defining discoveries of the past to tell the story of our most vital organ. He looks at some of the pioneers who risked their careers and their patients’ lives to better understand the heart. People like Daniel Hale Williams, who performed the world’s first documented heart surgery, and Wilson Greatbatch, who accidentally invented the pacemaker.Amid gripping scenes from the operating theatre, Jauhar interweaves stories about the patients he’s treated with the moving tale of his family’s own history of heart problems, from his grandfather’s sudden death in India – an event that sparked his life-long obsession – to the ominous signs of how he himself might die.He also confronts the limits of medical technology and argues that future progress will be determined more by how we choose to live rather than by any device we invent.

    As swiftly as it came, it disappeared, leaving no trace. Over the four decades since, Ebola has emerged sporadically, each time to devastating effect. It can kill up to 90 percent of its victims. In between these outbreaks, it is untraceable, hiding deep in the jungle. The search is on to find Ebola’s elusive host animal. And until we find it, Ebola will continue to strike. Acclaimed science writer and explorer David Quammen first came near the virus while he was traveling in the jungles of Gabon, accompanied by local men whose village had been devastated by a recent outbreak. Here he tells the story of Ebola—its past, present, and its unknowable future.Extracted from Spillover by David Quammen, updated and with additional material.

    We are most familiar with the viruses that give us colds or the flu, but viruses also cause a vast range of other diseases, including one disorder that makes people sprout branch-like growths as if they were trees. Viruses have been a part of our lives for so long, in fact, that we are actually part virus: the human genome contains more DNA from viruses than our own genes. Meanwhile, scientists are discovering viruses everywhere they look: in the soil, in the ocean, even in caves miles underground.This fascinating book explores the hidden world of viruses—a world that we all inhabit. Here Carl Zimmer, popular science writer and author of Discover magazine’s award-winning blog The Loom, presents the latest research on how viruses hold sway over our lives and our biosphere, how viruses helped give rise to the first life-forms, how viruses are producing new diseases, how we can harness viruses for our own ends, and how viruses will continue to control our fate for years to come. In this eye-opening tour of the frontiers of biology, where scientists are expanding our understanding of life as we know it, we learn that some treatments for the common cold do more harm than good; that the world’s oceans are home to an astonishing number of viruses; and that the evolution of HIV is now in overdrive, spawning more mutated strains than we care to imagine.The New York Times Book Review calls Carl Zimmer “as fine a science essayist as we have.” A Planet of Viruses is sure to please his many fans and further enhance his reputation as one of America’s most respected and admired science journalists.

    In Missing Microbes, Dr. Martin Blaser invites us into the wilds of the human microbiome where for hundreds of thousands of years bacterial and human cells have existed in a peaceful symbiosis that is responsible for the health and equilibrium of our body. Now, this invisible eden is being irrevocably damaged by some of our most revered medical advances—antibiotics—threatening the extinction of our irreplaceable microbes with terrible health consequences. Taking us into both the lab and deep into the fields where these troubling effects can be witnessed firsthand, Blaser not only provides cutting edge evidence for the adverse effects of antibiotics, he tells us what we can do to avoid even more catastrophic health problems in the future. http://us.macmillan.com/missingmicrob...

    In the midst of all this death, a bizarre disease appeared in Europe. Eventually known as encephalitis lethargica, or sleeping sickness, it would spread across the world, leaving millions dead or locked in institutions. Then, in 1927, it would disappear as suddenly as it had arrived-or so the doctors at first thought. Asleep, set in 1920s and '30s New York, follows a group of neurologists through hospitals and insane asylums as they try to solve this worldwide epidemic. The symptoms could include not only unending sleep but dangerous insomnia, facial tics, catatonia, Parkinson's, and even violent insanity. Molly Caldwell Crosby, acclaimed author of The American Plague, explores the frightening history of this forgotten disease- and details the frantic effort to conquer it before it strikes again.

    The Allies won the war with it. It conquered diseases, changed laws, and single-handedly launched the era of antibiotics. This incredible discovery was sulfa, the first antibiotic. In The Demon Under the Microscope, Thomas Hager chronicles the dramatic history of the drug that shaped modern medicine.Sulfa saved millions of lives—among them those of Winston Churchill and Franklin Delano Roosevelt Jr.—but its real effects are even more far reaching. Sulfa changed the way new drugs were developed, approved, and sold; transformed the way doctors treated patients; and ushered in the era of modern medicine. The very concept that chemicals created in a lab could cure disease revolutionized medicine, taking it from the treatment of symptoms and discomfort to the eradication of the root cause of illness. A strange and colorful story, The Demon Under the Microscope illuminates the vivid characters, corporate strategy, individual idealism, careful planning, lucky breaks, cynicism, heroism, greed, hard work, and the central (though mistaken) idea that brought sulfa to the world. This is a fascinating scientific tale with all the excitement and intrigue of a great suspense novel. For thousands of years, humans had sought medicines with which they could defeat contagion, and they had slowly, painstakingly, won a few battles: some vaccines to ward off disease, a handful of antitoxins. A drug or two was available that could stop parasitic diseases once they hit, tropical maladies like malaria and sleeping sickness. But the great killers of Europe, North America, and most of Asia—pneumonia, plague, tuberculosis, diphtheria, cholera, meningitis—were caused not by parasites but by bacteria, much smaller, far different microorganisms. By 1931, nothing on earth could stop a bacterial infection once it started. . . .But all that was about to change. . . . —from The Demon Under the Microscope

    Richard Rhodes follows virus hunters on three continents as they track the emergence of a deadly new brain disease that first kills cannibals in New Guinea, then cattle and young people in Britain and France—and that has already been traced to food animals in the United States. In a new afterword for the paperback, Rhodes reports the latest US and worldwide developments of a burgeoning global threat.

    Cory Franklin. Filled with stories of strange medical cases and unforgettable patients culled from a thirty-year career in medicine, Cook County ICU offers readers a peek into the inner workings of a hospital. Author Dr. Cory Franklin, who headed the hospital’s intensive care unit from the 1970s through the 1990s, shares his most unique and bizarre experiences, including the deadly Chicago heat wave of 1995, treating some of the first AIDS patients in the country before the disease was diagnosed, the nurse with rare Munchausen syndrome, the first surviving ricin victim, and the famous professor whose Parkinson’s disease hid the effects of the wrong medication. Surprising, darkly humorous, heartwarming, and sometimes tragic, these stories provide a big-picture look at how the practice of medicine has changed over the years, making it an enjoyable read for patients, doctors, and anyone with an interest in medicine.

    Close worked desperately to contain the outbreak. Haunted by this wrenching crisis, Dr. Close felt compelled to honor the memory of the courageous people he knew and lost. This is their story: a terrifying, completely authentic novel that begins with an invisible killer.  It strikes without warning—a lethal disease with no name . . . and no cure.   At a Catholic mission in Yambuku, a remote village sixty miles south of the Ebola River, local teacher Mabalo Lokela visits the clinic with a raging fever. Sister Lucie, a Flemish nun and nurse, gives him a shot of an antimalarial drug, wipes off the syringe, and awaits her next patient. Within days, Mabalo is dead. Soon, others are falling ill. Less than three weeks later, the virus claims Sister Lucie’s life as well. Panic erupts, but as the villagers attempt to flee, all roads leading out of Yambuku are closed off, the dying forced back. And as the single radio connecting the mission to the outside world brings only bad news, the valiant nuns and medical personnel left behind have no choice but to pray, and wonder: Will they survive long enough for help to arrive?

    In this sensational and macabre story, we meet the surgeon who counted not only luminaries Benjamin Franklin, Lord Byron, Adam Smith, and Thomas Gainsborough among his patients but also “resurrection men” among his close acquaintances. A captivating portrait of his ruthless devotion to uncovering the secrets of the human body, and the extraordinary lengths to which he went to do so—including body snatching, performing pioneering medical experiments, and infecting himself with venereal disease—this rich historical narrative at last acknowledges this fascinating man and the debt we owe him today.

    Yet despite a century of medical progress, viral and bacterial disasters continue to take us by surprise, inciting panic and dominating news cycles. From the Spanish flu to the 1924 outbreak of pneumonic plague in Los Angeles to the 1930 “parrot fever” pandemic, through the more recent SARS, Ebola, and Zika epidemics, the last one hundred years have been marked by a succession of unanticipated pandemic alarms.In The Pandemic Century, a lively account of scares both infamous and less known, Mark Honigsbaum combines reportage with the history of science and medical sociology to artfully reconstruct epidemiological mysteries and the ecology of infectious diseases. We meet dedicated disease detectives, obstructive or incompetent public health officials, and brilliant scientists often blinded by their own knowledge of bacteria and viruses. We also see how fear of disease often exacerbates racial, religious, and ethnic tensions—even though, as the epidemiologists Malik Peiris and Yi Guan write, “‘nature’ remains the greatest bioterrorist threat of all.”Like man-eating sharks, predatory pathogens are always present in nature, waiting to strike; when one is seemingly vanquished, others appear in its place. These pandemics remind us of the limits of scientific knowledge, as well as the role that human behavior and technologies play in the emergence and spread of microbial diseases.