The case would become one of the most famous in modern medicine—and a total failure. As Nature Made Him tells the extraordinary story of David Reimer, who, when finally informed of his medical history, made the decision to live as a male. A macabre tale of medical arrogance, it is first and foremost a human drama of one man's—and one family's—amazing survival in the face of terrible odds.

    Chartered by Queen Elizabeth I, their colony was to establish a foothold for England in the New World. But by the time the colony's leader, John White, returned to Roanoke from a resupply mission in England, his settlers were nowhere to be found. They had vanished into the wilderness, leaving behind only a single clue--the word "Croatoan" carved into a tree. The disappearance of the Lost Colony became an enduring American mystery. For four centuries, it has gone unsolved, obsessing countless historians, archeologists, and amateur sleuths. Today, after centuries of searching in vain, new clues have begun to surface. In The Secret Token, Andrew Lawler offers a beguiling history of the Lost Colony, and of the relentless quest to bring its fate to light. He accompanies competing archeologists as they seek out evidence, each team hoping to be the first to solve the riddle. In the course of his journey, Lawler explores how the Lost Colony came to haunt our national consciousness, working its way into literature, popular culture, and politics. Incisive and absorbing, The Secret Token offers a new understanding not just of the Lost Colony, but of how its absence continues to define--and divide--America.

    Today Ron Ball and I are romantically involved, it read, but I fear I have placed myself at risk in a variety of ways. Based on his criminal past, writing this out just seems like the smart thing to do. If I am missing or dead this obviously has not protected me... That same spring Janine Latus was struggling to leave her marriage -- a marriage to a handsome and successful man. A marriage others emulated. A marriage in which she felt she could do nothing right and everything wrong. A marriage in which she felt afraid, controlled, inadequate, and trapped. Ten weeks later, Janine Latus had left her marriage. She was on a business trip to the East Coast, savoring her freedom, attending a work conference, when she received a call from her sister Jane asking if she'd heard from Amy. Immediately, Janine's blood ran cold. Amy was missing. Helicopters went up and search dogs went out. Coworkers and neighbors and family members plastered missing posters with Amy's picture across the county. It took more than two weeks to find Amy's body, wrapped in a tarpaulin and buried at a building site. It took nearly two years before her killer, her former boyfriend Ron Ball, was sentenced for her murder. Amy died in silent fear and pain. Haunted by this, Janine Latus turned her journalistic eye inward. How, she wondered, did two seemingly well-adjusted, successful women end up in strings of physically or emotionally abusive relationships with men? If I Am Missing or Dead is a heart-wrenching journey of discovery as Janine Latus traces the roots of her own -- and her sister's -- victimization with unflinching candor. This beautifully written memoir will move readers from the first to the last page. At once a confession, a call to break the cycle of abuse, and a deeply felt love letter to her baby sister, Amy Lynne Latus, If I Am Missing or Dead is an unforgettable read.

    In Wicked Plants, Stewart takes on over two hundred of Mother Nature’s most appalling creations. It’s an A to Z of plants that kill, maim, intoxicate, and otherwise offend. You’ll learn which plants to avoid (like exploding shrubs), which plants make themselves exceedingly unwelcome (like the vine that ate the South), and which ones have been killing for centuries (like the weed that killed Abraham Lincoln's mother). Menacing botanical illustrations and splendidly ghastly drawings create a fascinating portrait of the evildoers that may be lurking in your own backyard. Drawing on history, medicine, science, and legend, this compendium of bloodcurdling botany will entertain, alarm, and enlighten even the most intrepid gardeners and nature lovers.

    . . . I’ve been kidnapped, and I’ve been missing for ten years.”   A horrifying story rapidly unfolded. Ariel Castro, a local school bus driver, had separately lured Berry, Gina DeJesus, and Michelle Knight to his home, where he kept them chained. In the decade that followed, the three were raped, psychologically abused, and threatened with death. Berry had a daughter—Jocelyn—by their captor.   Drawing upon their recollections and the diary kept by Amanda Berry, Berry and Gina DeJesus describe a tale of unimaginable torment, and Pulitzer Prize–winning Washington Post reporters Mary Jordan and Kevin Sullivan interweave the events within Castro’s house with original reporting on efforts to find the missing girls. The full story behind the headlines—including details never previously released on Castro’s life and motivations—Hope is a harrowing yet inspiring chronicle of two women whose courage, ingenuity, and resourcefulness ultimately delivered them back to their lives and families.

    Bundy's chilling revelations were chronicled in "The Riverman," "a page-turner" (Ted Montgomery, Detroit News ) praised by Ann Rule as "the definitive book on serials." But Ted Bundy wasn't the first killer of his kind - or the last "Signature Killers"They leave telltale identifiers, their gruesome "calling cards, " at the scenes of their crime. They are driven by a primitive motivation to act out the same brutality over and over. With brilliant detection, high-tech analysis - and a little luck - they can be caught. But what does the signature killer seek from victim to victim? The answers are hidden among the grisly evidence, the common threads that link each devastating act.Sparked by a growing concern over the steady rise of signature murders, Robert Keppel explores in unflinching detail the monstrous patterns, sadistic compulsions, and depraved motives of this breed of killer. From the Lonely Hearts Killer who hunted the most desperate of women in 1950s America, to the savage Midtown Torso Murders that stunned the NYPD, to such infamous symbols of evil as Jeffrey Dahmer, Ted Bundy, and John Gacy, these are the cases - horrifying, graphic and unforgettable - that Keppel ingeniously taps to shed light on the darkest corners of the pathological mind.

    The following winter, her dismembered remains were found buried in a seaside cave. The seven months in between had seen a massive search for the missing girl, involving Japanese policemen; British private detectives; Australian dowsers; and Lucie's desperate, but bitterly divided, parents. As the case unfolded, it drew the attention of prime ministers and sado-masochists, ambassadors and con-men, and reporters from across the world. Had Lucie been abducted by a religious cult, or snatched by human traffickers? Who was the mysterious man she had gone to meet? And what did her work, as a "hostess" in the notorious Roppongi district of Tokyo, really involve?Richard Lloyd Parry, an award-winning foreign correspondent, followed the case since Lucie's disappearance. Over the course of a decade, he traveled to four continents to interview those caught up in the story, fought off a legal attack in the Japanese courts, and worked undercover as a bartender in a Roppongi strip club. He talked exhaustively with Lucie's friends and family and won unique access to the Japanese detectives who investigated the case. And he delved into the mind and background of the man accused of the crime--Joji Obara, described by the judge as "unprecedented and extremely evil." With the finesse of a novelist, he reveals the astonishing truth about Lucie and her fate. People Who Eat Darkness is, by turns, a non-fiction thriller, a courtroom drama, and the biography of both a victim and a killer. It is the story of a young woman who fell prey to unspeakable evil, and of a loving family torn apart by grief. And it is a fascinating insight into one of the world's most baffling and mysterious societies, a light shone into dark corners of Japan that the rest of the world has never glimpsed before.

    From distressed small communities in Central Appalachia to wealthy suburbs; from disparate cities to once-idyllic farm towns; it's a heartbreaking trajectory that illustrates how this national crisis has persisted for so long and become so firmly entrenched. Beginning with a single dealer who lands in a small Virginia town and sets about turning high school football stars into heroin overdose statistics, Macy endeavors to answer a grieving mother's question-why her only son died-and comes away with a harrowing story of greed and need. From the introduction of OxyContin in 1996, Macy parses how America embraced a medical culture where overtreatment with painkillers became the norm. In some of the same distressed communities featured in her bestselling book Factory Man, the unemployed use painkillers both to numb the pain of joblessness and pay their bills, while privileged teens trade pills in cul-de-sacs, and even high school standouts fall prey to prostitution, jail, and death.Through unsparing, yet deeply human portraits of the families and first responders struggling to ameliorate this epidemic, each facet of the crisis comes into focus. In these politically fragmented times, Beth Macy shows, astonishingly, that the only thing that unites Americans across geographic and class lines is opioid drug abuse. But in a country unable to provide basic healthcare for all, Macy still finds reason to hope-and signs of the spirit and tenacity necessary in those facing addiction to build a better future for themselves and their families.

    At first, she toughed it out through searing pain, taking sick days from work, unable to leave the bathroom or her bed. But when it became undeniable that something was seriously wrong, Miller gave in to family pressure and went to the hospital—beginning a yearslong nightmare of procedures, misdiagnoses, and life-threatening infections. Once she was finally correctly diagnosed with Crohn’s disease, Miller faced another battle: accepting that she will never get better.Today, an astonishing three in five adults in the United States suffer from a chronic disease—a percentage expected to rise post-Covid. Whether the illness is arthritis, asthma, Crohn's, diabetes, endometriosis, multiple sclerosis, ulcerative colitis, or any other incurable illness, and whether the sufferer is a colleague, a loved one, or you, these diseases have an impact on just about every one of us. Yet there remains an air of shame and isolation about the topic of chronic sickness. Millions must endure these disorders not only physically but also emotionally, balancing the stress of relationships and work amid the ever-present threat of health complications.Miller segues seamlessly from her dramatic personal experiences into a frank look at the cultural realities (medical, occupational, social) inherent in receiving a lifetime diagnosis. She offers hard-earned wisdom, solidarity, and an ultimately surprising promise of joy for those trying to make sense of it all.

    Gang Leader for a Day is the fascinating full story of how Sudhir Venkatesh managed to gain entrée into the gang, what he learned, and how his method revolutionized the academic establishment. When Venkatesh walked into an abandoned building in one of Chicago's most notorious housing projects, he was looking for people to take a multiple-choice survey on urban poverty. A first-year grad student, he would befriend a gang leader named JT and spend the better part of the next decade inside the projects under JT's protection, documenting what he saw there. Over the next seven years, Venkatesh observed JT and the rest of the gang as they operated their crack selling business, conducted PR within their community, and rose up or fell within the ranks of the gang's complex organizational structure. Gang Leader for a Day is an inside view into the morally ambiguous, highly intricate, often corrupt struggle to survive in an urban war zone. It is also the story of a complicated friendship between two young and ambitious men, a universe apart.

    What does that do to the spirit of individuals and community? Drawing on his decades of experience, Alex Kotlowitz set out to chronicle one summer in the city, writing about individuals who have emerged from the violence and whose stories capture the capacity--and the breaking point--of the human heart and soul. The result is a spellbinding collection of deeply intimate profiles that upend what we think we know about gun violence in America. Among others, we meet a man who as a teenager killed a rival gang member and twenty years later is still trying to come to terms with what he's done; a devoted school social worker struggling with her favorite student, who refuses to give evidence in the shooting death of his best friend; the witness to a wrongful police shooting who can't shake what he has seen; and an aging former gang leader who builds a place of refuge for himself and his friends. Applying the close-up, empathic reporting that made There Are No Children Here a modern classic, Kotlowitz offers a piercingly honest portrait of a city in turmoil. These sketches of those left standing will get into your bones. This one summer will stay with you.

    Your head hurts. You're mildly annoyed as you get the kids ready for school and dress for work yourself. Meanwhile, an epic war is being fought, just below your skin. Millions are fighting and dying for you to be able to complain as you head out the door.So what, exactly, is your immune system?Second only to the human brain in its complexity, it is one of the oldest and most critical facets of life on Earth. Without it, you would die within days. In Immune, Philipp Dettmer, the brains behind the most popular science channel on YouTube, takes readers on a journey through the fortress of the human body and its defenses. There is a constant battle of staggering scale raging within us, full of stories of invasion, strategy, defeat, and noble self-sacrifice. In fact, in the time you've been reading this, your immune system has probably identified and eradicated a cancer cell that started to grow in your body.Each chapter delves into an element of the immune system, including defenses like antibodies and inflammation as well as threats like bacteria, allergies, and cancer, as Dettmer reveals why boosting your immune system is actually nonsense, how parasites sneak their way past your body's defenses, how viruses work, and what goes on in your wounds when you cut yourself.Enlivened by engaging graphics and immersive descriptions, Immune turns one of the most intricate, interconnected, and confusing subjects—immunology—into a gripping adventure through an astonishing alien landscape. Immune is a vital and remarkably fun crash course in what is arguably, and increasingly, the most important system in the body.

    We follow Strauss as he explores his startling past-collision life - the funeral, the queasy drama of a high-stakes court case? and what starts as a personal tale of a tragic event opens into the story of how to live with a very hard fact: we can try our human best in the crucial moment, and it might not be good enough. Half a Life is a nakedly honest, ultimately hopeful examination of guilt, responsibility, and living with the past.

    As the creator and star of Mister Rogers’ Neighborhood, he was a champion of compassion, equality, and kindness. Rogers was fiercely devoted to children and to taking their fears, concerns, and questions about the world seriously.The Good Neighbor, the first full-length biography of Fred Rogers, tells the story of this utterly unique and enduring American icon. Drawing on original interviews, oral histories, and archival documents, Maxwell King traces Rogers’s personal, professional, and artistic life through decades of work, including a surprising decision to walk away from the show to make television for adults, only to return to the neighborhood with increasingly sophisticated episodes, written in collaboration with experts on childhood development. An engaging story, rich in detail, The Good Neighbor is the definitive portrait of a beloved figure, cherished by multiple generations.

    From one of the top cave divers working today—and one of the very few women in her field—Into the Planet blends science, adventure, and memoir to bring readers face-to-face with the terror and beauty of earth’s remaining unknowns and the extremes of human capability.Jill Heinerth—the first person in history to dive deep into an Antarctic iceberg and leader of a team that discovered the ancient watery remains of Mayan civilizations—has descended farther into the inner depths of our planet than any other woman. She takes us into the harrowing split-second decisions that determine whether a diver makes it back to safety, the prejudices that prevent women from pursuing careers underwater, and her endeavor to recover a fallen friend’s body from the confines of a cave. But there’s beauty beyond the danger of diving, and while Heinerth swims beneath our feet in the lifeblood of our planet, she works with biologists discovering new species, physicists tracking climate change, and hydrogeologists examining our finite freshwater reserves. Written with hair-raising intensity, Into the Planet is the first book to deliver an intimate account of cave diving, transporting readers deep into inner space, where fear must be reconciled and a mission’s success balances between knowing one’s limits and pushing the envelope of human endurance.