It has built on itself for centuries, becoming vast and increasingly specialized. Most of us are ignorant about the fundamental principles of the civilization that supports us, happily utilizing the latest—or even the most basic—technology without having the slightest idea of why it works or how it came to be. If you had to go back to absolute basics, like some sort of postcataclysmic Robinson Crusoe, would you know how to re-create an internal combustion engine, put together a microscope, get metals out of rock, accurately tell time, weave fibers into clothing, or even how to produce food for yourself? Regarded as one of the brightest young scientists of his generation, Lewis Dartnell proposes that the key to preserving civilization in an apocalyptic scenario is to provide a quickstart guide, adapted to cataclysmic circumstances. The Knowledge describes many of the modern technologies we employ, but first it explains the fundamentals upon which they are built. Every piece of technology rests on an enormous support network of other technologies, all interlinked and mutually dependent. You can’t hope to build a radio, for example, without understanding how to acquire the raw materials it requires, as well as generate the electricity needed to run it. But Dartnell doesn’t just provide specific information for starting over; he also reveals the greatest invention of them all—the phenomenal knowledge-generating machine that is the scientific method itself. This would allow survivors to learn technological advances not explicitly explored in The Knowledge as well as things we have yet to discover. The Knowledge is a brilliantly original guide to the fundamentals of science and how it built our modern world as well as a thought experiment about the very idea of scientific knowledge itself.

    Many people think of microbes as germs to be eradicated, but those that live with us—the microbiome—build our bodies, protect our health, shape our identities, and grant us incredible abilities. In this astonishing book, Ed Yong takes us on a grand tour through our microbial partners, and introduces us to the scientists on the front lines of discovery. Yong, whose humor is as evident as his erudition, prompts us to look at ourselves and our animal companions in a new light—less as individuals and more as the interconnected, interdependent multitudes we assuredly are. The microbes in our bodies are part of our immune systems and protect us from disease. Those in cows and termites digest the plants they eat. In the deep oceans, mysterious creatures without mouths or guts depend on microbes for all their energy. Bacteria provide squids with invisibility cloaks, help beetles to bring down forests, and allow worms to cause diseases that afflict millions of people. I Contain Multitudes is the story of these extraordinary partnerships, between the creatures we are familiar with and those we are not. It reveals how we humans are disrupting these partnerships and how we might manipulate them for our own good. It will change both our view of nature and our sense of where we belong in it.

    But gravitational waves – ripples in the fabric of space and time – are unrelenting, passing through barriers that stop light dead.At the two 4-kilometre long LIGO observatories in the US, scientists developed incredibly sensitive detectors, capable of spotting a movement 100 times smaller than the nucleus of an atom. In 2015 they spotted the ripples produced by two black holes spiralling into each other, setting spacetime quivering.This was the first time black holes had ever been directly detected – and it promises far more for the future of astronomy. Brian Clegg presents a compelling story of human technical endeavour and a new, powerful path to understand the workings of the universe.Brian Clegg’s most recent books are The Reality Frame (Icon, 2017), What Colour is the Sun? (Icon, 2016) and Ten Billion Tomorrows (St Martin’s Press, 2016). His Dice World and A Brief History of Infinity were both longlisted for the Royal Society Prize for Science Books. He has also written Big Data for the Hot Science series. Brian has written for numerous publications including The Wall Street Journal, Nature, BBC Focus, Physics World, The Times and The Observer. Brian is editor of popularscience.co.uk and blogs at brianclegg.blogspot.com.

    But if we are supposedly evolution’s greatest creation, why do we have such bad knees? Why do we catch head colds so often—two hundred times more often than a dog does? How come our wrists have so many useless bones? Why is the vast majority of our genetic code pointless? And are we really supposed to swallow and breathe through the same narrow tube? Surely there’s been some kind of mistake. As professor of biology Nathan H. Lents explains in Human Errors, our evolutionary history is nothing if not a litany of mistakes, each more entertaining and enlightening than the last. The human body is one big pile of compromises. But that is also a testament to our greatness: as Lents shows, humans have so many design flaws precisely because we are very, very good at getting around them.   A rollicking, deeply informative tour of humans’ four billion year long evolutionary saga, Human Errors both celebrates our imperfections and offers an unconventional accounting of the cost of our success.

    If you want to understand the greatest ideas that shaped our current cosmic cartography, read this book.”—Adam G. Riess, Nobel Laureate in Physics, 2011   This book provides a tour of the “greatest hits” of cosmological discoveries—the ideas that reshaped our universe over the past century. The cosmos, once understood as a stagnant place, filled with the ordinary, is now a universe that is expanding at an accelerating pace, propelled by dark energy and structured by dark matter. Priyamvada Natarajan, our guide to these ideas, is someone at the forefront of the research—an astrophysicist who literally creates maps of invisible matter in the universe. She not only explains for a wide audience the science behind these essential ideas but also provides an understanding of how radical scientific theories gain acceptance.   The formation and growth of black holes, dark matter halos, the accelerating expansion of the universe, the echo of the big bang, the discovery of exoplanets, and the possibility of other universes—these are some of the puzzling cosmological topics of the early twenty-first century. Natarajan discusses why the acceptance of new ideas about the universe and our place in it has never been linear and always contested even within the scientific community. And she affirms that, shifting and incomplete as science always must be, it offers the best path we have toward making sense of our wondrous, mysterious universe.

    Twelve astronauts made this greatest of all journeys and were indelibly marked by it, for better or for worse. Journalist Andrew Smith tracks down the nine surviving members of this elite group to find their answers to the question "Where do you go after you've been to the Moon?"A thrilling blend of history, reportage, and memoir, Moondust rekindles the hopeful excitement of an incandescent hour in America's past and captures the bittersweet heroism of those who risked everything to hurl themselves out of the known world -- and who were never again quite able to accept its familiar bounds.

    It has been inspired by the scientific ferment that swept through Britain at the end of the 18th century, and which Holmes now radically redefines as 'the revolution of Romantic Science'.

    Rather, they recruited an elite group of young women who, with only pencil, paper, and mathematical prowess, transformed rocket design, helped bring about the first American satellites, and made the exploration of the solar system possible. For the first time, Rise of the Rocket Girls tells the stories of these women--known as "human computers"--who broke the boundaries of both gender and science. Based on extensive research and interviews with all the living members of the team, Rise of the Rocket Girls offers a unique perspective on the role of women in science: both where we've been, and the far reaches of space to which we're heading.

    It intersects with Darwin’s theory of evolution, and collides with the horrors of Nazi eugenics in the 1940s. The gene transforms post-war biology. It reorganizes our understanding of sexuality, temperament, choice and free will. This is a story driven by human ingenuity and obsessive minds – from Charles Darwin and Gregor Mendel to Francis Crick, James Watson and Rosalind Franklin, and the thousands of scientists still working to understand the code of codes.This is an epic, moving history of a scientific idea coming to life, by the author of The Emperor of All Maladies. But woven through The Gene, like a red line, is also an intimate history – the story of Mukherjee’s own family and its recurring pattern of mental illness, reminding us that genetics is vitally relevant to everyday lives. These concerns reverberate even more urgently today as we learn to “read” and “write” the human genome – unleashing the potential to change the fates and identities of our children.Majestic in its ambition, and unflinching in its honesty, The Gene gives us a definitive account of the fundamental unit of heredity – and a vision of both humanity’s past and future.

    . . full of intellectual treats and tricks, of whimsy and deep scientific philosophy. It is highbrow entertainment at its best, a teasing challenge to all who aspire to think about the universe." — New York Herald TribuneOne of the world's foremost nuclear physicists (celebrated for his theory of radioactive decay, among other accomplishments), George Gamow possessed the unique ability of making the world of science accessible to the general reader.He brings that ability to bear in this delightful expedition through the problems, pleasures, and puzzles of modern science. Among the topics scrutinized with the author's celebrated good humor and pedagogical prowess are the macrocosm and the microcosm, theory of numbers, relativity of space and time, entropy, genes, atomic structure, nuclear fission, and the origin of the solar system.In the pages of this book readers grapple with such crucial matters as whether it is possible to bend space, why a rocket shrinks, the "end of the world problem," excursions into the fourth dimension, and a host of other tantalizing topics for the scientifically curious. Brimming with amusing anecdotes and provocative problems, One Two Three . . . Infinity also includes over 120 delightful pen-and-ink illustrations by the author, adding another dimension of good-natured charm to these wide-ranging explorations.Whatever your level of scientific expertise, chances are you'll derive a great deal of pleasure, stimulation, and information from this unusual and imaginative book. It belongs in the library of anyone curious about the wonders of the scientific universe. "In One Two Three . . . Infinity, as in his other books, George Gamow succeeds where others fail because of his remarkable ability to combine technical accuracy, choice of material, dignity of expression, and readability." — Saturday Review of Literature

    Radiation: What could go wrong? In short, plenty. From Marie Curie carrying around a vial of radium salt because she liked the pretty blue glow to the large-scale disasters at Chernobyl and Fukushima, dating back to the late nineteenth century, nuclear science has had a rich history of innovative exploration and discovery, coupled with mistakes, accidents, and downright disasters. In this lively book, long-time advocate of continued nuclear research and nuclear energy James Mahaffey looks at each incident in turn and analyzes what happened and why, often discovering where scientists went wrong when analyzing past meltdowns. Every incident, while taking its toll, has led to new understanding of the mighty atom—and the fascinating frontier of science that still holds both incredible risk and great promise.

    In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field—the study of life’s diversity and relatedness at the molecular level—is horizontal gene transfer (HGT), or the movement of genes across species lines. It turns out that HGT has been widespread and important. For instance, we now know that roughly eight percent of the human genome arrived not through traditional inheritance from directly ancestral forms, but sideways by viral infection—a type of HGT.David Quammen chronicles these discoveries through the lives of the researchers who made them—such as Carl Woese, the most important little-known biologist of the twentieth century; Lynn Margulis, the notorious maverick whose wild ideas about “mosaic” creatures proved to be true; and Tsutomu Wantanabe, who discovered that the scourge of antibiotic-resistant bacteria is a direct result of horizontal gene transfer, bringing the deep study of genome histories to bear on a global crisis in public health.

    We wouldn’t have unraveled DNA or discovered Neptune or figured out how to put 5,000 songs in your pocket. Though many of us were scared away from this essential, engrossing subject in high school and college, Steven Strogatz’s brilliantly creative, down‑to‑earth history shows that calculus is not about complexity; it’s about simplicity. It harnesses an unreal number—infinity—to tackle real‑world problems, breaking them down into easier ones and then reassembling the answers into solutions that feel miraculous. Infinite Powers recounts how calculus tantalized and thrilled its inventors, starting with its first glimmers in ancient Greece and bringing us right up to the discovery of gravitational waves (a phenomenon predicted by calculus). Strogatz reveals how this form of math rose to the challenges of each age: how to determine the area of a circle with only sand and a stick; how to explain why Mars goes “backwards” sometimes; how to make electricity with magnets; how to ensure your rocket doesn’t miss the moon; how to turn the tide in the fight against AIDS. As Strogatz proves, calculus is truly the language of the universe. By unveiling the principles of that language, Infinite Powers makes us marvel at the world anew.

    Beneath the frozen crusts of several of the small, ice-covered moons of Jupiter and Saturn lurk vast oceans that may have been in existence for as long as Earth, and together may contain more than fifty times its total volume of liquid water. Could there be organisms living in their depths? Alien Oceans reveals the science behind the thrilling quest to find out.Kevin Peter Hand is one of today's leading NASA scientists, and his pioneering research has taken him on expeditions around the world. In this captivating account of scientific discovery, he brings together insights from planetary science, biology, and the adventures of scientists like himself to explain how we know that oceans exist within moons of the outer solar system, like Europa, Titan, and Enceladus. He shows how the exploration of Earth's oceans is informing our understanding of the potential habitability of these icy moons, and draws lessons from what we have learned about the origins of life on our own planet to consider how life could arise on these distant worlds.Alien Oceans describes what lies ahead in our search for life in our solar system and beyond, setting the stage for the transformative discoveries that may await us.

    Lisa Sanders, author of the monthly New York Times Magazine column "Diagnosis," the inspiration for the hit Fox TV series House, M.D.The experience of being ill can be like waking up in a foreign country. Life, as you formerly knew it, is on hold while you travel through this other world as unknown as it is unexpected. When I see patients in the hospital or in my office who are suddenly, surprisingly ill, what they really want to know is, ‘What is wrong with me?’ They want a road map that will help them manage their new surroundings. The ability to give this unnerving and unfamiliar place a name, to know it–on some level–restores a measure of control, independent of whether or not that diagnosis comes attached to a cure. Because, even today, a diagnosis is frequently all a good doctor has to offer.A healthy young man suddenly loses his memory–making him unable to remember the events of each passing hour. Two patients diagnosed with Lyme disease improve after antibiotic treatment–only to have their symptoms mysteriously return. A young woman lies dying in the ICU–bleeding, jaundiced, incoherent–and none of her doctors know what is killing her. In Every Patient Tells a Story, Dr. Lisa Sanders takes us bedside to witness the process of solving these and other diagnostic dilemmas, providing a firsthand account of the expertise and intuition that lead a doctor to make the right diagnosis.Never in human history have doctors had the knowledge, the tools, and the skills that they have today to diagnose illness and disease. And yet mistakes are made, diagnoses missed, symptoms or tests misunderstood. In this high-tech world of modern medicine, Sanders shows us that knowledge, while essential, is not sufficient to unravel the complexities of illness. She presents an unflinching look inside the detective story that marks nearly every illness–the diagnosis–revealing the combination of uncertainty and intrigue that doctors face when confronting patients who are sick or dying. Through dramatic stories of patients with baffling symptoms, Sanders portrays the absolute necessity and surprising difficulties of getting the patient’s story, the challenges of the physical exam, the pitfalls of doctor-to-doctor communication, the vagaries of tests, and the near calamity of diagnostic errors. In Every Patient Tells a Story, Dr. Sanders chronicles the real-life drama of doctors solving these difficult medical mysteries that not only illustrate the art and science of diagnosis, but often save the patients’ lives.