America faced a troubling question: What happened? How was this epidemic allowed to spread so far before it was taken seriously? In answering these questions, Shilts weaves the disparate threads into a coherent story, pinning down every evasion and contradiction at the highest levels of the medical, political, and media establishments. Shilts shows that the epidemic spread wildly because the federal government put budget ahead of the nation's welfare; health authorities placed political expediency before the public health; and scientists were often more concerned with international prestige than saving lives. Against this backdrop, Shilts tells the heroic stories of individuals in science and politics, public health and the gay community, who struggled to alert the nation to the enormity of the danger it faced. And the Band Played On is both a tribute to these heroic people and a stinging indictment of the institutions that failed the nation so badly.

    We are most familiar with the viruses that give us colds or the flu, but viruses also cause a vast range of other diseases, including one disorder that makes people sprout branch-like growths as if they were trees. Viruses have been a part of our lives for so long, in fact, that we are actually part virus: the human genome contains more DNA from viruses than our own genes. Meanwhile, scientists are discovering viruses everywhere they look: in the soil, in the ocean, even in caves miles underground.This fascinating book explores the hidden world of viruses—a world that we all inhabit. Here Carl Zimmer, popular science writer and author of Discover magazine’s award-winning blog The Loom, presents the latest research on how viruses hold sway over our lives and our biosphere, how viruses helped give rise to the first life-forms, how viruses are producing new diseases, how we can harness viruses for our own ends, and how viruses will continue to control our fate for years to come. In this eye-opening tour of the frontiers of biology, where scientists are expanding our understanding of life as we know it, we learn that some treatments for the common cold do more harm than good; that the world’s oceans are home to an astonishing number of viruses; and that the evolution of HIV is now in overdrive, spawning more mutated strains than we care to imagine.The New York Times Book Review calls Carl Zimmer “as fine a science essayist as we have.” A Planet of Viruses is sure to please his many fans and further enhance his reputation as one of America’s most respected and admired science journalists.

    Doctors, nurses, and clinicians swear by this code of conduct. Yet, medical errors are made every single day-avoidable mistakes that often cost lives. Inspired by two such mistakes, Dr. Peter Pronovost made it his personal mission to improve patient safety and make preventable deaths a thing of the past, one hospital at a time. Safe Patients, Smart Hospitals shows how Dr. Pronovost started a revolution by creating a simple checklist that standardized a common ICU procedure. His reforms are being implemented in all fifty states and have saved hundreds of lives by cutting hospital-acquired infection rates by 70%. Atul Gawande profiled Dr. Pronovost's reforms in a New Yorker article and his bestselling book The Checklist Manifesto is based upon Dr. Pronovost's success in patient safety. But Safe Patients, Smart Hospitals is the real story: an inspiring, thought-provoking, accessible insider's narrative about how doctors and nurses are improving patient care for all Americans, today.

    In Never Home Alone, biologist Rob Dunn introduces us to the nearly 200,000 species living with us in our own homes, from the Egyptian meal moths in our cupboards and camel crickets in our basements to the lactobacillus lounging on our kitchen counters. You are not alone. Yet, as we obsess over sterilizing our homes and separating our spaces from nature, we are unwittingly cultivating an entirely new playground for evolution. These changes are reshaping the organisms that live with us -- prompting some to become more dangerous, while undermining those species that benefit our bodies or help us keep more threatening organisms at bay. No one who reads this engrossing, revelatory book will look at their homes in the same way again.

    Or, as #1 New York Times bestselling author and celebrity trainer Jorge Cruise explains: When we eat is as important as what we eat. Building on the scientifically proven but hard-to-sustain day-on, day-off technique known as "intermittent fasting," Cruise simplifies your calendar by dividing every day into two easy-to-remember nutritional zones: a 16-hour evening and overnight "burn zone" (semi-fasting) followed by an 8-hour "boost zone" (eating). To help you crush cravings throughout, he ingeniously introduces foods that can be consumed in either zone to keep you burning fat all around the clock. You'll never be hungry if you don't really ever have to fully fast! Putting the body on weight-loss autopilot, The Cruise Control Diet includes: * 50 recipes for deliciously unexpected boost-zone foods, such as Margherita pizza, spaghetti squash lasagna, and turmeric shrimp;* 15 high-fat, no-sugar burn-zone recipes for craving-quenching foods like chocolate coconut mousse and caramel chai latte;* Weekly menus and handy grocery lists to take guessing out of the equation;* Candid testimonials and amazing weight loss results from Cruise's clients;* An optional burn-zone exercise program with instructional photos.

    Backed by investors such as Larry Ellison and Tim Draper, Theranos sold shares in a fundraising round that valued the company at $9 billion, putting Holmes's worth at an estimated $4.7 billion. There was just one problem: The technology didn't work.For years, Holmes had been misleading investors, FDA officials, and her own employees. When Carreyrou, working at The Wall Street Journal, got a tip from a former Theranos employee and started asking questions, both Carreyrou and the Journal were threatened with lawsuits. Undaunted, the newspaper ran the first of dozens of Theranos articles in late 2015. By early 2017, the company's value was zero and Holmes faced potential legal action from the government and her investors. Here is the riveting story of the biggest corporate fraud since Enron, a disturbing cautionary tale set amid the bold promises and gold-rush frenzy of Silicon Valley.

    It has found adherents in Silicon Valley billionaires Ray Kurzweil and Peter Diamandis. Google has entered the picture, establishing a bio-tech subsidiary aimed at solving the problem of aging.In To Be a Machine, journalist Mark O'Connell takes a headlong dive into this burgeoning movement. He travels to the laboratories, conferences, and basements of today's foremost transhumanists, where he's presented with the staggering possibilities and moral quandaries of new technologies like mind uploading, artificial superintelligence, cryonics, and device implants.A contributor to Slate, The New Yorker, and The New York Times Magazine, O'Connell serves as a sharp and lively guide to the outer limits of technology in the twenty first century. In investigating what it means to be a machine, he offers a surprising, singular meditation on what it means to be human."

    Women crave intimacy and emotional connection. Women don't want sex with strangers. Right? Wrong. Could 'the fairer sex' in fact be more sexually aggressive and anarchic than men? In What Do Women Want? Adventures in the Science of Female Desire, critically acclaimed journalist Daniel Bergner looks at the evidence. Recent research, he finds, dismantles the myths to reveal an unprecedented portrait of female lust- the triggers, the fantasies, the mind-body connection (and disconnection), the reasons behind the loss of libido and, most revelatory, that this loss is not inevitable.

    In a clear and accessible style, Frank M. Snowden reveals the ways that diseases have not only influenced medical science and public health, but also transformed the arts, religion, intellectual history, and warfare. A multidisciplinary and comparative investigation of the medical and social history of the major epidemics, this volume touches on themes such as the evolution of medical therapy, plague literature, poverty, the environment, and mass hysteria. In addition to providing historical perspective on diseases such as smallpox, cholera, and tuberculosis, Snowden examines the fallout from recent epidemics such as HIV/AIDS, SARS, and Ebola and the question of the world’s preparedness for the next generation of diseases.

    Nadine Burke Harris was already known as a crusading physician delivering targeted care to vulnerable children. But it was Diego — a boy who had stopped growing after a sexual assault — who galvanized her journey to uncover the connections between toxic stress and lifelong illnesses.The news of Burke Harris’s research is just how deeply our bodies can be imprinted by ACEs—adverse childhood experiences like abuse, neglect, parental addiction, mental illness, and divorce. Childhood adversity changes our biological systems, and lasts a lifetime.  For anyone who has faced a difficult childhood, or who cares about the millions of children who do, the scientific insight and innovative, acclaimed health interventions in The Deepest Well represent hope for preventing lifelong illness for those we love and for generations to come​.

    Shannon, Wally, and John built their lives around their place of work. Shannon, a white single mother, became the first woman to run the dangerous furnaces at the Rexnord manufacturing plant in Indianapolis, Indiana, and was proud of producing one of the world’s top brands of steel bearings. Wally, a black man known for his initiative and kindness, was promoted to chairman of efficiency, one of the most coveted posts on the factory floor, and dreamed of starting his own barbecue business one day. John, a white machine operator, came from a multigenerational union family and clashed with a work environment that was increasingly hostile to organized labor. The Rexnord factory had served as one of the economic engines for the surrounding community. When it closed, hundreds of people lost their jobs. What had life been like for Shannon, Wally, and John, before the plant shut down? And what became of them after the jobs moved to Mexico and Texas? American Made is the story of a community struggling to reinvent itself. It is also a story about race, class, and American values, and how jobs serve as a bedrock of people’s lives and drive powerful social justice movements. This revealing book shines a light on this political moment, when joblessness and uncertainty about the future of work have made themselves heard at a national level. Most of all, it is a story about people: who we consider to be one of us and how the dignity of work lies at the heart of who we are.

    For the first time, the major developed economies began to invest more in intangible assets, like design, branding, R&D, and software, than in tangible assets, like machinery, buildings, and computers. For all sorts of businesses, from tech firms and pharma companies to coffee shops and gyms, the ability to deploy assets that one can neither see nor touch is increasingly the main source of long-term success.But this is not just a familiar story of the so-called new economy. Capitalism without Capital shows that the growing importance of intangible assets has also played a role in some of the big economic changes of the last decade. The rise of intangible investment is, Jonathan Haskel and Stian Westlake argue, an underappreciated cause of phenomena from economic inequality to stagnating productivity.Haskel and Westlake bring together a decade of research on how to measure intangible investment and its impact on national accounts, showing the amount different countries invest in intangibles, how this has changed over time, and the latest thinking on how to assess this. They explore the unusual economic characteristics of intangible investment, and discuss how these features make an intangible-rich economy fundamentally different from one based on tangibles.Capitalism without Capital concludes by presenting three possible scenarios for what the future of an intangible world might be like, and by outlining how managers, investors, and policymakers can exploit the characteristics of an intangible age to grow their businesses, portfolios, and economies.

    By spinning 28 mathematical tales, Orlin shows us that calculus is simply another language to express the very things we humans grapple with every day -- love, risk, time, and most importantly, change. Divided into two parts, "Moments" and "Eternities," and drawing on everyone from Sherlock Holmes to Mark Twain to David Foster Wallace, Change is the Only Constant unearths connections between calculus, art, literature, and a beloved dog named Elvis. This is not just math for math's sake; it's math for the sake of becoming a wiser and more thoughtful human.

    I was left with such an unusual feeling that I didn't at first realise what it was, and then I remembered: optimism. I hope everyone with the slightest interest in the way the world works will read it' PHILIP PULLMAN ______Good news: the solutions to our problems already exist.Great news: a once-in-a-generation appetite for change means we can make them happen.The challenges we face are daunting, but in Go Big Ed Miliband shows that the scale of what is possible is far greater. We are at a rare moment in history when people everywhere see the need for big change. Meanwhile, practical and proven ways exist for tackling everything from inequality to the climate crisis - if you know where to look and have the courage to think big.Ed Miliband has captured imaginations with his award-winning hit podcast Reasons to be Cheerful, which discovers brilliant people all around the world who are successfully fixing problems, transforming communities and pioneering global movements. From a citizens' assembly in Mongolia to the UK's largest walking and cycling network in Greater Manchester, from flexible working in Finland to the campaign for the first halal Nando's in Cardiff, Go Big draws on the most imaginative and ambitious of these ideas to provide a vision for how to remake society. The future is not yet written. It's our job to write it. Go Big shows us how. ______'Inspired and inspiring, Miliband calls upon us to rise to our challenges with courageous boldness' CHRISTIANA FIGUERES, Lead Negotiator of the UN Paris Climate Agreement''Go big' should be the rallying cry of progressives around the world' RUTGER BREGMAN, author of Humankind*A Guardian, Evening Standard and New Statesman Book to Look Out for in 2021*_____(*WARNING - Contains genuinely big ideas that may inspire* Solutions cover: Green New Deal - Affordable Housing - Universal Social Inheritance - A Care Economy - Reining In Big Tech - Citizens' Assemblies - Votes At 16 - A Devolution Revolution - Fossil Fuel Divestment - Community Wealth Building and many, many more)

    Reeves (a biographer of Mill) and Haidt (a social psychologist) summarize Mill's three timeless arguments for free speech and the value of viewpoint diversity. They then reduce the text to half its original length, allowing Mill's best arguments and metaphors to shine. Artist Dave Cicirelli illustrates those metaphors to amplify their intuitive power. Ideal for use in college courses, or in any organization in which people would benefit from productive disagreement.