The work has as basis the fact that the nervous system behaves adap tively and the hypothesis that it is essentiaIly mechanistic; it proceeds on the assumption that these two data are not irrecon cilable. It attempts to deduce from the observed facts what sort of a mechanism it must be that behaves so differently from any machinc made so far. Other proposed solutions have usuaIly left open the question whether so me different theory might not fit the facts equaIly weIl: I have attempted to deduce what is necessary, what properties the nervous system must have if it is to behave at once mechanisticaIly and adaptively. For the deduction to be rigorous, an adequately developed logic of mechanism is essential. Until recently, discussions of mechan ism were carried on almost entirely in terms of so me particular embodiment-the mechanical, the electronic, the neuronie, and so on. Those days are past. There now exists a weIl-developed logic of pure mechanism, rigorous as geometry, and likely to play the same fundamental part, in our understanding of the complex systems of biology, that geometry does in astronomy. Only by the dcvelopment of this basic logic has thc work in this book been made possible."

    In Knowledge of Life, a book that spans twenty years of his essays and lectures, Canguilhem offers a series of epistemological histories that seek to establish and clarify the stakes, ambiguities, and emergence of philosophical and biological concepts that defined the rise of modern biology.How do transformations in biology and modern medicine shape conceptions of life? How do philosophical concepts feed into biological ideas and experimental practices, and how are they themselves transformed? How does knowledge "undo the experience of life so as to help man remake what life has made without him, in him or outside of him?" Knowledge of Life is Canguilhem's effort to explain how the movements of knowledge and life come to rest upon each other.Published at the dawn of the genetic revolution and still pertinent today, the book tackles the history of cell theory, the conceptual moves toward and away from mechanical understandings of the organism, the persistence of vitalism, and the nature of normality in science and its objects.